| Human synonyms | PEDS1 | CarF|KUA|TMEM189 | GeneID:387521 | ENSG00000240849 | 0 |
| Mouse ortholog | Tmem189 | AI840826|Kua | GeneID:407243 | ENSMUSG00000090213 | Q99LQ7 |
| Tissue Atlas Coexpression | human GTEx RNA, mouse GNFv3 RNA, mouse protein |
| CCLE cell lines | CRISPR-codependency, RNA-seq coexpression, RNA-microarray, CRISPR-vs-RNA-seq |
| Sequence Alignment (MitoCarta only) | all_BBH, selected_BBH |
| In MitoCarta3.0? | 0 |
| Evidence | 0 |
| MitoPathway | |
| Sub-Mito Localization | |
| MS/MS tissues | |
| MitoCarta2.0 FDR | 0.887 |
| MitoCarta2.0 Training | Tnon_mito |
| TargetP_v1 MTS Confidence | |
| MitoDomain | NonMitoDomain |
| Yeast Homolog | NoMitoHomolog |
| Rickettsia Homolog | NoHomolog |
| GeneAtlas Coexpression N50 | 0 |
| PGC Induction | |
| MSMS score | |
| MSMS intensity | cerebrum:, cerebellum:, brainstem:, spinalcord:, kidney:, liver:, heart:, muscle:, adipose:, sm_intestine:, lg_intestine:, stomach:, placenta:, testis: |
| MSMS unique peps | |
| Curator notes |
| HPA Main Location (2020) | Endoplasmic reticulum (Supported) |
| PFAM domains (2022) | Lipid_desat |
| CRISPR guides |
| Glu/Gal Death Screen (2016) | not strongly enriched in Gal/Glu dead cells (fdr=1) |
| O2 Screen Summary (2020) | Selectively essential in 21% vs 1% oxygen (fdr=0.0002) |
| 1%O2_vs_21%O2.day15.score (2020) | -3.7 |
| 21%O2.day15_vs_day0.score (2020) | 0 |
| Chemical Genetics Zscore (To 2019) | |
| TMRM Oligo Zscore (unpublished) |
| Species | mRNA | ProteinID | Len (AA) | TargetP v1.0 | TargetP v2.0 | TPpred2 | MitoFates | Mouse Best | TMHMM # Helices | TMHMM Topology |
|---|---|---|---|---|---|---|---|---|---|---|
| mouse | NM_145538 | NP_663513 | 271 | no pred (conf=2) | noTP | noMTS (score=1) | 2 | o47-69i76-98o | ||
| human | NM_199129 | NP_954580 | 270 | no pred (conf=2) | noTP | noMTS (score=1) | 3 | o46-68i75-97o165-182i | ||
| human | NM_001162505 | NP_001155977 | 267 | no pred (conf=2) | noTP | noMTS (score=1) | 3 | o46-68i75-97o162-179i |
