Shown are top 300 and bottom 300 genes based on Pearson correlation between this gene and 17672 other genes using cancer dependency profiles (dependency across 391 cancer cell lines). Bold indicates MitoCarta2.0 gene. Note that if this gene is always expressed (CDM meanD>0.9) or rarely expressed (CDM meanD<0.1) then these correlations are unlikely to be useful, as they are probably driven by one or two outlier cell lines. CDM dependency is a score between 0 (no growth defect in cell line) and 1 (extreme growth defect in cell line). TPM is a log2 representation of RNA-seq expression.

Rank Corr Symbol Description MitoCarta2.0 CDM meanD CDM range TPM mean TPM range Entrez UniProt

1 1 TMEM189 transmembrane protein 189 0 0.02 0-0.68 4.8 2.3-8.7 387521

2 0.714 TBCK TBC1 domain containing kinase 0 0.03 0-0.9 2.9 -0.2-5.3 93627 Q8TEA7

3 0.713 SERPINB1 "serpin peptidase inhibitor, clade B (ovalbumin), member 1" 0 0.01 0-0.28 4.1 -3-10.4 1992 P30740

4 0.698 SEC14L1 SEC14-like 1 (S. cerevisiae) 0 0.03 0-0.76 5 2.1-8.7 6397 Q92503

5 0.635 SMPD2 "sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)" 0 0.02 0-0.61 3 -1.6-5.6 6610 O60906

6 0.621 MICU1 mitochondrial calcium uptake 1 1 0.03 0-0.73 5.2 3.1-7.2 10367 Q9BPX6

7 0.616 C2CD2L C2CD2-like 0 0.01 0-0.52 3 -0.7-6.5 9854 O14523

8 0.609 ICAM1 intercellular adhesion molecule 1 0 0.02 0-0.89 2.6 -3-9.3 3383 P05362

9 0.602 SOX12 SRY (sex determining region Y)-box 12 0 0.02 0-0.66 3.6 -2.3-6.5 6666 O15370

10 0.594 HIF1A "hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)" 0 0.01 0-0.58 6.3 -1.6-9.7 3091 Q16665

11 0.589 TYK2 tyrosine kinase 2 0 0.01 0-0.7 6.1 3.9-8.5 7297 P29597

12 0.573 AGFG1 ArfGAP with FG repeats 1 0 0.04 0-0.91 5.4 3.1-7.4 3267 P52594

13 0.560 ZNF610 zinc finger protein 610 0 0.01 0-0.26 -0.6 -3-4.3 162963 Q8N9Z0

14 0.559 ITSN2 intersectin 2 0 0.02 0-0.44 3.9 1.8-6.6 50618 Q9NZM3

15 0.555 PML promyelocytic leukemia 0 0.02 0-0.96 4.4 1.8-7.1 5371 P29590

16 0.553 SLC5A3 "solute carrier family 5 (sodium/myo-inositol cotransporter), member 3" 0 0.06 0-1 0 -3-4.6 6526

17 0.544 ABHD5 abhydrolase domain containing 5 0 0.02 0-0.41 3.4 -3-7.3 51099 Q8WTS1

18 0.524 ABHD12 abhydrolase domain containing 12 0 0.04 0-0.82 5.5 2.4-7.9 26090 Q8N2K0

19 0.510 AGAP4 "ArfGAP with GTPase domain, ankyrin repeat and PH domain 4" 0 0 0-0.12 2.2 -3-5 119016 Q96P64

20 0.505 GFI1 growth factor independent 1 transcription repressor 0 0.06 0-0.89 -0.2 -3-8.5 2672 Q99684

21 0.501 LPCAT4 lysophosphatidylcholine acyltransferase 4 0 0.03 0-0.56 5.2 2.1-7.9 254531 Q643R3

22 0.498 PPP1R21 "protein phosphatase 1, regulatory subunit 21" 0 0.04 0-0.56 3.4 1.4-5.5 129285 Q6ZMI0

23 0.491 KLHDC2 kelch domain containing 2 0 0.02 0-0.23 4.8 2.6-6.8 23588 Q9Y2U9

24 0.479 ZGLP1 "zinc finger, GATA-like protein 1" 0 0.04 0-0.73 0.7 -3-5 100125288 P0C6A0

25 0.477 CALM3 "calmodulin 3 (phosphorylase kinase, delta)" 0 0.04 0-0.78 808 Q9BRL5

26 0.466 PLA2G4C "phospholipase A2, group IVC (cytosolic, calcium-independent)" 0 0.01 0-0.29 0.6 -3-5.6 8605 Q9UP65

27 0.460 SULT2A1 "sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1" 0 0.02 0-0.39 -2.9 -3-7.2 6822 Q06520

28 0.459 DDHD2 DDHD domain containing 2 0 0.03 0-0.66 5 2-7.9 23259 O94830

29 0.456 ELSPBP1 epididymal sperm binding protein 1 0 0.02 0-0.42 -2.8 -3-7.2 64100 Q96BH3

30 0.443 CYTH2 cytohesin 2 0 0.04 0-0.67 5.3 3.2-7.3 9266 Q99418

31 0.441 PCSK2 proprotein convertase subtilisin/kexin type 2 0 0.01 0-0.12 -2.3 -3-9.1 5126 P16519

32 0.423 LRP8 "low density lipoprotein receptor-related protein 8, apolipoprotein e receptor" 0 0.12 0-0.99 4.5 -0.4-8.1 7804 Q14114

33 0.422 C10orf88 chromosome 10 open reading frame 88 0 0.04 0-0.57 2.8 -1.7-4.7 80007 Q9H8K7

34 0.421 SPACA4 sperm acrosome associated 4 0 0.08 0-0.95 -2.4 -3-3 171169 Q8TDM5

35 0.419 SIK3 SIK family kinase 3 0 0.03 0-0.9 3.3 -3-6 23387 Q9Y2K2

36 0.419 EPN1 epsin 1 0 0.04 0-0.61 5.9 0.4-8.2 29924 Q9Y6I3

37 0.418 MBD3L5 methyl-CpG binding domain protein 3-like 5 0 0.01 0-0.12 -3 -3-4.2 284428 A6NJ08

38 0.415 WDR72 WD repeat domain 72 0 0.01 0-0.21 -0.6 -3-6.6 256764 Q3MJ13

39 0.415 NPRL2 nitrogen permease regulator-like 2 (S. cerevisiae) 0 0.04 0-0.73 4.1 -3-5.8 10641 Q8WTW4

40 0.414 SAP30 "Sin3A-associated protein, 30kDa" 0 0.02 0-0.59 4.2 -3-7.3 8819 O75446

41 0.412 SYNGR4 synaptogyrin 4 0 0.03 0-0.6 -1.9 -3-8.4 23546 O95473

42 0.407 GSS glutathione synthetase 0 0.03 0-0.61 5.7 2.4-9.1 2937 P48637

43 0.406 VRK3 vaccinia related kinase 3 0 0.02 0-0.37 4.7 2.5-6.8 51231 Q8IV63

44 0.404 LPCAT1 lysophosphatidylcholine acyltransferase 1 0 0.02 0-0.44 5.4 -2.8-10.1 79888 Q8NF37

45 0.402 NARF nuclear prelamin A recognition factor 0 0.05 0-0.57 5.6 3.4-9.4 26502 Q9UHQ1

46 0.398 GNG8 "guanine nucleotide binding protein (G protein), gamma 8" 0 0.04 0-0.65 -2.6 -3-5.6 94235 Q9UK08

47 0.396 MEIS1 Meis homeobox 1 0 0.05 0-0.87 1.2 -3-7.6 4211 O00470

48 0.396 IKZF1 IKAROS family zinc finger 1 (Ikaros) 0 0.02 0-0.98 -1.3 -3-7.8 10320 Q13422

49 0.394 SEC23B Sec23 homolog B (S. cerevisiae) 0 0.08 0-0.99 5.5 3.4-7.9 10483 Q15437

50 0.394 PEX12 peroxisomal biogenesis factor 12 0 0.05 0-0.8 2 -3-3.9 5193 O00623

51 0.391 DEPDC5 DEP domain containing 5 0 0.01 0-0.5 3.6 0.6-6.3 9681 O75140

52 0.389 SLC8A2 "solute carrier family 8 (sodium/calcium exchanger), member 2" 0 0.03 0-0.57 -2 -3-5.9 6543 Q9UPR5

53 0.387 PPP3CB "protein phosphatase 3, catalytic subunit, beta isozyme" 0 0.01 0-0.12 4.3 2.2-6.1 5532 P16298

54 0.387 PHF11 PHD finger protein 11 0 0.01 0-0.08 3.3 -3-8.3 51131 Q9UIL8

55 0.387 ATP6V0D2 "ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2" 0 0.01 0-0.21 -2.4 -3-5.2 245972 Q8N8Y2

56 0.386 KLHL28 kelch-like family member 28 0 0.02 0-0.17 1.9 -0.7-4.3 54813 Q9NXS3

57 0.385 DCLRE1A DNA cross-link repair 1A 0 0.01 0-0.15 2.7 -1-6.4 9937 Q6PJP8

58 0.380 PNMAL2 paraneoplastic Ma antigen family-like 2 0 0.03 0-0.44 -2.7 -3-2.7 57469 Q9ULN7

59 0.378 UROS uroporphyrinogen III synthase 0 0.19 0-0.94 5.2 2.6-7.3 7390 P10746

60 0.377 PTPRH "protein tyrosine phosphatase, receptor type, H" 0 0.02 0-0.33 0.7 -3-6.7 5794

61 0.377 DEFB125 "defensin, beta 125" 0 0.02 0-0.19 -3 -3--0.7 245938 Q8N687

62 0.376 USP17L2 ubiquitin specific peptidase 17-like family member 2 0 0.01 0-0.21 -3 -3-1.3 377630 Q6R6M4

63 0.376 TMEM189-UBE2V1 TMEM189-UBE2V1 readthrough 0 0.28 0.01-0.92 -2.7 -3-0.2 387522

64 0.376 CA11 carbonic anhydrase XI 0 0.09 0-0.95 2.7 -3-7.9 770 O75493

65 0.374 STX8 syntaxin 8 0 0.03 0-0.31 5.2 -2.2-8 9482 Q9UNK0

66 0.374 ICAM3 intercellular adhesion molecule 3 0 0.06 0-0.85 3.5 -0.7-8.4 3385 P32942

67 0.374 DHX40 DEAH (Asp-Glu-Ala-His) box polypeptide 40 0 0.05 0-0.85 4.6 -2.8-7.2 79665 Q8IX18

68 0.372 CYB5A cytochrome b5 type A (microsomal) 1 0.01 0-0.96 5.1 -3-9.4 1528 P00167

69 0.365 IGFL3 IGF-like family member 3 0 0.01 0-0.17 -2.7 -3-8.9 388555 Q6UXB1

70 0.364 LILRA1 "leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1" 0 0.01 0-0.19 -2.8 -3-4.9 11024 O75019

71 0.362 ZFP64 ZFP64 zinc finger protein 0 0.04 0-0.72 3.9 1.6-7.3 55734 Q9NPA5

72 0.361 WDR81 WD repeat domain 81 1 0.01 0-0.74 3.2 -3-5.8 124997 Q562E7

73 0.359 MYPOP "Myb-related transcription factor, partner of profilin" 0 0.04 0-0.72 2 -0.6-4.4 339344 Q86VE0

74 0.357 RSPH10B radial spoke head 10 homolog B (Chlamydomonas) 0 0.01 0-0.2 -2.4 -3-1.4 222967 P0C881

75 0.357 AGPS alkylglycerone phosphate synthase 0 0.03 0-0.45 4.1 -3-6.6 8540 O00116

76 0.354 STAT5B signal transducer and activator of transcription 5B 0 0.09 0-0.93 4.3 -3-8.3 6777 P51692

77 0.353 ZNF486 zinc finger protein 486 0 0.04 0-0.46 -0.1 -3-4.9 90649 Q96H40

78 0.353 ZFP36 ZFP36 ring finger protein 0 0.02 0-0.65 4.4 -1.9-9.7 7538 P26651

79 0.350 CLCN3 "chloride channel, voltage-sensitive 3" 0 0.01 0-0.29 4.3 0.9-6.7 1182 P51790

80 0.349 SNAP25 "synaptosomal-associated protein, 25kDa" 0 0.01 0-0.19 -0.4 -3-7.8 6616 P60880

81 0.348 RASIP1 Ras interacting protein 1 0 0.07 0-0.76 -1 -3-5.9 54922 Q5U651

82 0.347 NSMAF neutral sphingomyelinase (N-SMase) activation associated factor 0 0.05 0-0.42 4.8 -2.5-7.8 8439 Q92636

83 0.346 RPS6KA1 "ribosomal protein S6 kinase, 90kDa, polypeptide 1" 0 0.16 0-0.97 4.3 -2.1-8 6195 Q15418

84 0.345 ZBTB21 zinc finger and BTB domain containing 21 0 0.01 0-0.31 2.5 -3-5 49854 Q9ULJ3

85 0.345 SLC19A1 "solute carrier family 19 (folate transporter), member 1" 0 0.05 0-0.67 4 -1.6-6.7 6573 P41440

86 0.344 TMEM160 transmembrane protein 160 0 0.05 0-0.67 3.8 0-6.8 54958 Q9NX00

87 0.342 STK17B serine/threonine kinase 17b 0 0.04 0-0.48 2.7 -3-7.7 9262 O94768

88 0.342 NT5DC2 5'-nucleotidase domain containing 2 1 0.09 0-0.9 6.1 -2.9-9 64943 Q9H857

89 0.341 PEX2 peroxisomal biogenesis factor 2 0 0.08 0-0.85 5.3 3.1-7.1 5828 P28328

90 0.341 C14orf39 chromosome 14 open reading frame 39 0 0.01 0-0.18 -2.4 -3-3.7 317761 Q8N1H7

91 0.339 SNX10 sorting nexin 10 0 0.01 0-0.14 2.5 -3-8 29887 Q9Y5X0

92 0.339 PTPLB "protein tyrosine phosphatase-like (proline instead of catalytic arginine), member b" 0 0.08 0-0.94 4.7 1.6-7.7 201562 Q6Y1H2

93 0.339 BLOC1S1 "biogenesis of lysosomal organelles complex-1, subunit 1" 1 0.03 0-0.41 6.7 -3-8.4 2647 P78537

94 0.338 AFTPH aftiphilin 0 0.03 0-0.41 3.8 1.9-6.1 54812 Q6ULP2

95 0.337 SH3GL1 SH3-domain GRB2-like 1 0 0.18 0-0.97 5.5 3.4-7.5 6455 Q99961

96 0.336 SNX9 sorting nexin 9 0 0.03 0-0.63 3.5 -3-6.8 51429 Q9Y5X1

97 0.335 NCKAP1L NCK-associated protein 1-like 0 0.09 0-0.93 -1.3 -3-7.6 3071 P55160

98 0.335 DENND4A DENN/MADD domain containing 4A 0 0.14 0-0.91 2.7 -0.4-6 10260 Q7Z401

99 0.334 AFF1 "AF4/FMR2 family, member 1" 0 0.01 0-0.29 3.3 -2.4-6.2 4299 P51825

100 0.333 TPRX1 tetra-peptide repeat homeobox 1 0 0.04 0-0.32 -3 -3-4.8 284355 Q8N7U7

101 0.333 FAM21A "family with sequence similarity 21, member A" 0 0.02 0-0.34 3.9 0.7-6 387680 Q641Q2

102 0.331 STRADA STE20-related kinase adaptor alpha 0 0.08 0-0.53 4.7 2.5-6.7 92335 Q7RTN6

103 0.330 RYR3 ryanodine receptor 3 0 0.02 0-0.23 -2.2 -3-4.6 6263 Q15413

104 0.330 PICALM phosphatidylinositol binding clathrin assembly protein 0 0.06 0-0.83 6.5 3.4-9.6 8301 Q13492

105 0.330 CKMT1B "creatine kinase, mitochondrial 1B" 1 0.01 0-0.17 1.2 -3-7.9 1159

106 0.327 VPS13A vacuolar protein sorting 13 homolog A (S. cerevisiae) 0 0.05 0-0.88 3.4 0.3-6.3 23230 Q96RL7

107 0.327 DEFB4B "defensin, beta 4B" 0 0.02 0-0.17 -2.9 -3-6.6 100289462

108 0.327 CERS2 ceramide synthase 2 0 0.24 0-0.99 7 4.6-10.9 29956 Q96G23

109 0.326 ZNF880 zinc finger protein 880 0 0 0-0.08 1.4 -3-6.4 400713 Q6PDB4

110 0.326 PSIP1 PC4 and SFRS1 interacting protein 1 0 0.04 0-0.84 5.9 -0.5-10.4 11168 O75475

111 0.325 SIRPG signal-regulatory protein gamma 0 0.02 0-0.33 -2.6 -3-6.5 55423 Q9P1W8

112 0.323 C10orf55 chromosome 10 open reading frame 55 0 0.03 0-0.25 -1.4 -3-3.8 414236 Q5SWW7

113 0.323 ASAH2 N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2 1 0.01 0-0.08 -0.3 -3-4 56624 Q9NR71

114 0.322 TBC1D14 "TBC1 domain family, member 14" 0 0.03 0-0.4 4.9 2.5-9 57533 Q9P2M4

115 0.321 IRF8 interferon regulatory factor 8 0 0.02 0-0.97 -1 -3-8.6 3394 Q02556

116 0.321 EVC2 Ellis van Creveld syndrome 2 0 0 0-0.04 -1.4 -3-4.6 132884 Q86UK5

117 0.320 GPRIN2 G protein regulated inducer of neurite outgrowth 2 0 0.19 0-0.92 -1.4 -3-5.6 9721 O60269

118 0.319 CTSA cathepsin A 0 0.02 0-0.14 6.9 3.9-10.1 5476 P10619

119 0.318 RTKN2 rhotekin 2 0 0.05 0-0.53 1.7 -3-5.4 219790 Q8IZC4

120 0.316 NPSR1 neuropeptide S receptor 1 0 0.01 0-0.12 -2.7 -3-7.1 387129 Q6W5P4

121 0.315 TYR tyrosinase 0 0.01 0-0.1 -2.5 -3-9.9 7299 P14679

122 0.315 KPTN kaptin (actin binding protein) 0 0.03 0-0.34 3.2 -0.1-6.1 11133 Q9Y664

123 0.314 C12orf71 chromosome 12 open reading frame 71 0 0.03 0-0.44 -2.8 -3-1.9 728858 A8MTZ7

124 0.313 REEP3 receptor accessory protein 3 0 0 0-0.08 3.6 -3-7.2 221035 Q6NUK4

125 0.312 ZNF587 zinc finger protein 587 0 0.04 0-0.35 3.8 0.6-7 84914 Q96SQ5

126 0.311 PEX7 peroxisomal biogenesis factor 7 0 0.11 0-0.91 2.5 -3-5.2 5191 O00628

127 0.311 LIPT2 lipoyl(octanoyl) transferase 2 (putative) 1 0.07 0-0.8 1.2 -3-4.9 387787 A6NK58

128 0.311 BCL2 B-cell CLL/lymphoma 2 1 0.05 0-0.91 0.9 -3-8.2 596 P10415

129 0.310 LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1 0 0.02 0-0.19 2.8 -3-6.3 23143 Q9Y2L9

130 0.308 SPI1 spleen focus forming virus (SFFV) proviral integration oncogene 0 0.08 0-0.99 -1.8 -3-8.3 6688 P17947

131 0.307 TET2 tet methylcytosine dioxygenase 2 0 0.01 0-0.05 1.9 -3-4.8 54790 Q6N021

132 0.307 NPAS1 neuronal PAS domain protein 1 0 0.05 0-0.57 1 -3-7.1 4861 Q99742

133 0.307 C3orf43 chromosome 3 open reading frame 43 0 0.01 0-0.11 -3 -3-1.4 255798 Q147U7

134 0.306 ZNF471 zinc finger protein 471 0 0 0-0.06 -1.1 -3-4.2 57573 Q9BX82

135 0.304 FUT1 "fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)" 0 0.07 0-0.86 -0.4 -3-6.8 2523 P19526

136 0.304 COMMD3-BMI1 COMMD3-BMI1 readthrough 0 0.06 0-0.46 4.6 -3-8.7 100532731 R4GMX3

137 0.304 AADAC arylacetamide deacetylase 0 0.01 0-0.14 -1.7 -3-8.1 13 P22760

138 0.303 ZNF443 zinc finger protein 443 0 0 0-0.05 0.8 -3-4.7 10224 Q9Y2A4

139 0.303 TRIM49D1 tripartite motif containing 49D1 0 0.02 0-0.45 -2.9 -3-2 399939

140 0.303 TRIM33 tripartite motif containing 33 0 0.06 0-0.74 3.8 1.6-7.3 51592 Q9UPN9

141 0.303 NTN5 netrin 5 0 0.07 0-0.62 -2.3 -3-2.8 126147 Q8WTR8

142 0.303 EBF3 early B-cell factor 3 0 0.06 0-0.8 -1.6 -3-6.5 253738 Q9H4W6

143 0.301 SPAG11B sperm associated antigen 11B 0 0.04 0-0.68 -3 -3-8.7 10407 Q08648

144 0.301 AP1G1 "adaptor-related protein complex 1, gamma 1 subunit" 0 0.12 0-0.96 5 2.2-7 164 O43747

145 0.300 OR2T2 "olfactory receptor, family 2, subfamily T, member 2" 0 0.1 0-0.72 -3 -3-0.4 401992 Q6IF00

146 0.300 CTXN2 cortexin 2 0 0.02 0-0.2 -2.9 -3-0.6 399697 P0C2S0

147 0.300 CGB2 "chorionic gonadotropin, beta polypeptide 2" 0 0.06 0-0.67 -2.1 -3-5.1 114336 H9KV56

148 0.299 LYPLAL1 lysophospholipase-like 1 1 0.02 0-0.25 3.7 -3-6.7 127018 Q5VWZ2

149 0.298 TCTE3 t-complex-associated-testis-expressed 3 0 0.03 0-0.3 -1.5 -3-1.7 6991 Q8IZS6

150 0.298 PPCDC phosphopantothenoylcysteine decarboxylase 0 0.19 0-0.99 4.1 1.8-7.3 60490 Q96CD2

151 0.297 C10orf113 chromosome 10 open reading frame 113 0 0 0-0.06 -3 -3-0.1 387638 Q5VZT2

152 0.296 WSB1 WD repeat and SOCS box containing 1 0 0.07 0-0.92 5.8 -1.8-8.5 26118 Q9Y6I7

153 0.296 ARL5B ADP-ribosylation factor-like 5B 0 0.01 0-0.11 2.9 0.2-5.3 221079 Q96KC2

154 0.295 MED13L mediator complex subunit 13-like 0 0.08 0-0.93 4.1 -3-6.7 23389 Q71F56

155 0.294 ALAD aminolevulinate dehydratase 0 0.09 0-0.97 4.2 1.2-7 210 P13716

156 0.292 RBP2 "retinol binding protein 2, cellular" 0 0.01 0-0.11 -2.6 -3-9.9 5948 P50120

157 0.292 FLI1 "Fli-1 proto-oncogene, ETS transcription factor" 0 0.04 0-0.78 0.1 -3-8 2313 Q01543

158 0.292 DCAF16 DDB1 and CUL4 associated factor 16 0 0.01 0-0.11 4.1 1.4-6.6 54876 Q9NXF7

159 0.291 QTRT1 queuine tRNA-ribosyltransferase 1 1 0.09 0-0.78 5.3 1.4-7.3 81890 Q9BXR0

160 0.291 AMY1A "amylase, alpha 1A (salivary)" 0 0 0-0.03 -3 -3-0.4 276 Q6NSB3

161 0.290 TMEM41A transmembrane protein 41A 0 0.1 0-0.94 3.9 1.4-6.7 90407 Q96HV5

162 0.290 PPP5C "protein phosphatase 5, catalytic subunit" 0 0.05 0-0.83 6.2 3.1-8 5536 P53041

163 0.290 HMHA1 histocompatibility (minor) HA-1 0 0.07 0-0.91 3.9 -0.2-8.5 23526 Q92619

164 0.290 DEFB103B "defensin, beta 103B" 0 0.01 0-0.28 -2.7 -3-4.5 55894

165 0.289 SEC31A SEC31 homolog A (S. cerevisiae) 0 0.05 0-0.87 6.3 3.3-8.3 22872 O94979

166 0.289 NPIPA7 "nuclear pore complex interacting protein family, member A7" 0 0.01 0-0.3 -0.2 -3-6.1 101059938

167 0.288 SLC24A5 "solute carrier family 24 (sodium/potassium/calcium exchanger), member 5" 0 0.02 0-0.31 -1.3 -3-8.1 283652 Q71RS6

168 0.288 SKAP2 src kinase associated phosphoprotein 2 0 0.01 0-0.06 3.9 -3-7.4 8935 O75563

169 0.288 PTPN7 "protein tyrosine phosphatase, non-receptor type 7" 0 0.1 0-0.73 -1.1 -3-8.4 5778 P35236

170 0.288 JADE2 jade family PHD finger 2 0 0.04 0-0.75 3.9 -2.4-7.1 23338 Q9NQC1

171 0.288 EMC10 ER membrane protein complex subunit 10 0 0.04 0-0.34 5.9 -3-9.3 284361 Q5UCC4

172 0.287 RPS6KA2 "ribosomal protein S6 kinase, 90kDa, polypeptide 2" 0 0.02 0-0.16 1.6 -3-7.2 6196 Q15349

173 0.287 RBM7 RNA binding motif protein 7 0 0.06 0-0.67 4.3 -2.3-6.5 10179 Q9Y580

174 0.287 KANK1 KN motif and ankyrin repeat domains 1 0 0.01 0-0.11 2.9 -3-7.4 23189 Q14678

175 0.287 HIST1H2AC "histone cluster 1, H2ac" 0 0.05 0-0.47 4.2 -3-9 8334 Q93077

176 0.285 ZNF700 zinc finger protein 700 0 0.02 0-0.21 2.8 -3-5 90592 Q9H0M5

177 0.285 A1CF APOBEC1 complementation factor 0 0.01 0-0.23 -2.5 -3-6.1 29974 Q9NQ94

178 0.284 TMEM135 transmembrane protein 135 0 0.02 0-0.16 3.4 -0.7-8.4 65084 Q86UB9

179 0.284 KIAA1551 KIAA1551 0 0.04 0-0.82 3.9 -0.5-8.5 55196 Q9HCM1

180 0.284 GNE glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase 0 0.03 0-0.35 3.1 -3-7.7 10020 Q9Y223

181 0.284 ARL15 ADP-ribosylation factor-like 15 0 0.01 0-0.2 2.6 -3-7.1 54622 Q9NXU5

182 0.283 IWS1 IWS1 homolog (S. cerevisiae) 0 0.12 0-0.92 5.2 3.6-6.8 55677 Q96ST2

183 0.283 GNG5 "guanine nucleotide binding protein (G protein), gamma 5" 1 0.15 0-0.99 7 4.4-8.9 2787 P63218

184 0.283 CDADC1 cytidine and dCMP deaminase domain containing 1 0 0.01 0-0.24 3.4 -3-5.6 81602 Q9BWV3

185 0.282 SGMS1 sphingomyelin synthase 1 0 0.03 0-0.65 3.1 -3-6.9 259230 Q86VZ5

186 0.282 IRF2BP2 interferon regulatory factor 2 binding protein 2 0 0.17 0-0.98 5.8 -2.3-9.1 359948 Q7Z5L9

187 0.281 CLCNKA "chloride channel, voltage-sensitive Ka" 0 0.02 0-0.27 -2.5 -3-7.1 1187 P51800

188 0.280 OR7D4 "olfactory receptor, family 7, subfamily D, member 4" 0 0.03 0-0.34 -3 -3--3 125958 Q8NG98

189 0.280 MTRNR2L2 MT-RNR2-like 2 0 0 0-0.06 -1.3 -3-8.1 100462981 P0CJ69

190 0.280 LPCAT3 lysophosphatidylcholine acyltransferase 3 0 0.16 0-0.96 4.9 2.2-8.3 10162 Q6P1A2

191 0.280 FLT3 fms-related tyrosine kinase 3 0 0.16 0-1 -2.4 -3-9.2 2322 P36888

192 0.280 CNN1 "calponin 1, basic, smooth muscle" 0 0.1 0-0.5 -1.1 -3-8.9 1264 P51911

193 0.279 TRIP10 thyroid hormone receptor interactor 10 0 0.03 0-0.59 5.1 -3-7.8 9322 Q15642

194 0.279 NME8 NME/NM23 family member 8 0 0.04 0-0.41 -2.7 -3-4 51314 Q8N427

195 0.279 GABARAPL2 GABA(A) receptor-associated protein-like 2 0 0.02 0-0.2 6.6 3.9-8.6 11345 P60520

196 0.279 C10orf131 chromosome 10 open reading frame 131 0 0.01 0-0.12 100127889 A6NCD4

197 0.278 TOP2B topoisomerase (DNA) II beta 180kDa 0 0.05 0-0.65 5.9 2.7-9.9 7155 Q02880

198 0.278 RNF167 ring finger protein 167 0 0.02 0-0.22 6.3 3.5-8.1 26001 Q9H6Y7

199 0.278 CTNS "cystinosin, lysosomal cystine transporter" 0 0.03 0-0.23 3.2 -3-7.2 1497 O60931

200 0.278 CHRFAM7A "CHRNA7 (cholinergic receptor, nicotinic, alpha 7, exons 5-10) and FAM7A (family with sequence similarity 7A, exons A-E) fusion" 0 0.02 0-0.2 -1.1 -3-5.2 89832 Q494W8

201 0.277 WDR91 WD repeat domain 91 0 0.05 0-0.97 3 -1.1-6.5 29062 A4D1P6

202 0.277 RALYL RALY RNA binding protein-like 0 0.04 0-0.25 -2.5 -3-6.4 138046 Q86SE5

203 0.277 RAB2B "RAB2B, member RAS oncogene family" 0 0.06 0-0.38 3.8 1.1-7 84932 Q8WUD1

204 0.277 MTMR9 myotubularin related protein 9 0 0.05 0-0.78 1.9 -3-5.2 66036 Q96QG7

205 0.277 ICAM5 "intercellular adhesion molecule 5, telencephalin" 0 0.07 0-0.73 1.2 -3-7.1 7087 Q9UMF0

206 0.277 EIF2AK1 eukaryotic translation initiation factor 2-alpha kinase 1 0 0.03 0-0.94 6 2.5-7.7 27102 Q9BQI3

207 0.277 DEFB4A "defensin, beta 4A" 0 0.07 0-0.72 -2.7 -3-7.5 1673

208 0.276 TXNRD3NB thioredoxin reductase 3 neighbor 0 0.04 0-0.33 645840 Q6F5E7

209 0.276 TRPM4 "transient receptor potential cation channel, subfamily M, member 4" 0 0.03 0-0.3 3.1 -3-7.6 54795 Q8TD43

210 0.276 TP53 tumor protein p53 0 0.06 0-0.9 5 -3-7.8 7157 P04637

211 0.276 IQGAP2 IQ motif containing GTPase activating protein 2 0 0.01 0-0.18 0.5 -3-8 10788 Q13576

212 0.276 CNOT4 "CCR4-NOT transcription complex, subunit 4" 0 0.07 0-0.8 3.1 1-4.5 4850 O95628

213 0.276 C5orf51 chromosome 5 open reading frame 51 0 0.01 0-0.13 3.6 -3-5.6 285636 A6NDU8

214 0.276 BSPH1 binder of sperm protein homolog 1 0 0.01 0-0.19 -3 -3-0.8 100131137 Q075Z2

215 0.276 ALAS1 "aminolevulinate, delta-, synthase 1" 1 0.09 0-0.91 5.2 3-8.6 211 P13196

216 0.275 RARA "retinoic acid receptor, alpha" 0 0.04 0-0.7 3.8 1.2-8.7 5914 P10276

217 0.275 PRKAA1 "protein kinase, AMP-activated, alpha 1 catalytic subunit" 0 0.03 0-0.97 5.4 1.7-7.6 5562 Q13131

218 0.275 GLTSCR1 glioma tumor suppressor candidate region gene 1 0 0.03 0-0.71 2.5 -2.5-6.3 29998 Q9NZM4

219 0.275 ARSJ "arylsulfatase family, member J" 0 0.01 0-0.09 1.2 -3-7.4 79642 Q5FYB0

220 0.274 PDE7A phosphodiesterase 7A 0 0.04 0-0.37 3.9 0.6-7.9 5150 Q13946

221 0.274 LRRC20 leucine rich repeat containing 20 0 0.01 0-0.16 3.2 -1.7-6.5 55222 Q8TCA0

222 0.274 LMO2 LIM domain only 2 (rhombotin-like 1) 0 0.03 0-0.98 -0.4 -3-8.7 4005 P25791

223 0.274 ITPR2 "inositol 1,4,5-trisphosphate receptor, type 2" 0 0.02 0-0.34 2.1 -3-7.4 3709 Q14571

224 0.274 IRF2BP1 interferon regulatory factor 2 binding protein 1 0 0.08 0-0.69 3.6 0.9-5.8 26145 Q8IU81

225 0.274 IREB2 iron-responsive element binding protein 2 0 0.12 0-0.97 4.3 2-6.2 3658 P48200

226 0.274 DAW1 dynein assembly factor with WDR repeat domains 1 0 0.01 0-0.16 -1.9 -3-6.1 164781 Q8N136

227 0.274 AIFM2 "apoptosis-inducing factor, mitochondrion-associated, 2" 1 0.07 0-0.75 3.1 -3-6.3 84883 Q9BRQ8

228 0.273 PGBD3 piggyBac transposable element derived 3 0 0.16 0-0.77 0.6 -3-4.8 267004

229 0.273 MEF2C myocyte enhancer factor 2C 0 0.04 0-1 1.1 -3-9.6 4208 Q06413

230 0.273 ATP8B3 "ATPase, aminophospholipid transporter, class I, type 8B, member 3" 0 0.05 0-0.4 1.2 -3-5.8 148229 O60423

231 0.272 FECH ferrochelatase 1 0.27 0-0.99 4.4 1-8.1 2235 P22830

232 0.272 FAM21C "family with sequence similarity 21, member C" 0 0.16 0-0.78 3.7 -2.2-5.8 253725 Q9Y4E1

233 0.272 EPS15 epidermal growth factor receptor pathway substrate 15 0 0.05 0-0.45 4.2 2.3-7 2060 P42566

234 0.271 RPS27L ribosomal protein S27-like 0 0.05 0-0.67 6.3 2.9-10.2 51065 Q71UM5

235 0.271 MTF1 metal-regulatory transcription factor 1 0 0.12 0-0.96 2.2 -0.3-5.8 4520 Q14872

236 0.271 FOXA3 forkhead box A3 0 0.03 0-0.45 -1.6 -3-6.2 3171 P55318

237 0.271 C11orf54 chromosome 11 open reading frame 54 0 0.01 0-0.06 3.9 1.2-6.6 28970 Q9H0W9

238 0.270 ZNF432 zinc finger protein 432 0 0.02 0-0.29 2.4 -3-6.3 9668 O94892

239 0.270 MORC3 MORC family CW-type zinc finger 3 0 0.01 0-0.26 3.5 -0.1-7.3 23515 Q14149

240 0.269 TSC2 tuberous sclerosis 2 0 0.19 0-0.97 5 2.3-7.4 7249 P49815

241 0.269 OR7A5 "olfactory receptor, family 7, subfamily A, member 5" 0 0 0-0.06 -2.9 -3-2.5 26659 Q15622

242 0.269 MTRNR2L5 MT-RNR2-like 5 0 0.05 0-0.32 -3 -3--3 100463289 P0CJ72

243 0.269 ANKRD26 ankyrin repeat domain 26 0 0 0-0.08 1.7 -1.6-4.6 22852 Q9UPS8

244 0.268 GPR83 G protein-coupled receptor 83 0 0.01 0-0.12 -2.7 -3-2.2 10888 Q9NYM4

245 0.268 CBFB "core-binding factor, beta subunit" 0 0.2 0-0.99 5.5 -1.3-7.7 865 Q13951

246 0.268 ADAMDEC1 "ADAM-like, decysin 1" 0 0.01 0-0.12 -2.9 -3-5.1 27299 O15204

247 0.267 ERGIC3 ERGIC and golgi 3 0 0.01 0-0.27 7.9 5.4-10.5 51614 Q9Y282

248 0.266 VPS8 vacuolar protein sorting 8 homolog (S. cerevisiae) 0 0.15 0-0.9 3.7 1.6-6.4 23355 Q8N3P4

249 0.266 SIGLEC11 sialic acid binding Ig-like lectin 11 0 0.06 0-0.57 -2.9 -3-3.4 114132 Q96RL6

250 0.266 NCLN nicalin 0 0.18 0-0.88 5.5 3.3-7.9 56926 Q969V3

251 0.266 M1AP meiosis 1 associated protein 0 0.03 0-0.35 -1.9 -3-5.7 130951 Q8TC57

252 0.265 SDCBP syndecan binding protein (syntenin) 0 0.06 0-0.57 6.4 -1.4-10.4 6386 O00560

253 0.265 MARCH6 "membrane-associated ring finger (C3HC4) 6, E3 ubiquitin protein ligase" 0 0.11 0-0.94 6.2 4-9 10299 O60337

254 0.265 LILRA2 "leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2" 0 0.01 0-0.32 -2.4 -3-7 11027 Q8N149

255 0.265 GAPVD1 GTPase activating protein and VPS9 domains 1 0 0.06 0-0.67 4.1 1.5-6 26130 Q14C86

256 0.265 FKRP fukutin related protein 0 0.07 0-0.62 3.8 1.3-6.2 79147 Q9H9S5

257 0.264 OR2T35 "olfactory receptor, family 2, subfamily T, member 35" 0 0.07 0-0.49 -3 -3--1.4 403244 Q8NGX2

258 0.264 MYB v-myb avian myeloblastosis viral oncogene homolog 0 0.3 0.01-1 1.4 -3-9.2 4602 P10242

259 0.264 CCNDBP1 cyclin D-type binding-protein 1 0 0.02 0-0.17 4.9 -2.5-8 23582 O95273

260 0.263 ZNF808 zinc finger protein 808 0 0.02 0-0.18 1.6 -3-4.7 388558 Q8N4W9

261 0.263 STEAP3 "STEAP family member 3, metalloreductase" 0 0.13 0-0.96 3.6 -3-7.6 55240 Q658P3

262 0.262 RCBTB1 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1 0 0.02 0-0.29 3.5 -3-7.4 55213 Q8NDN9

263 0.262 GDF2 growth differentiation factor 2 0 0.04 0-0.36 2658 Q9UK05

264 0.261 TLE2 "transducin-like enhancer of split 2 (E(sp1) homolog, Drosophila)" 0 0.02 0-0.15 1.5 -3-7.7 7089 Q04725

265 0.261 HTR4 "5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled" 0 0 0-0.04 -2.9 -3-4.2 3360 Q13639

266 0.261 CTDSPL2 "CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2" 0 0.17 0-0.98 4.1 1.4-6.5 51496 Q05D32

267 0.260 SLC24A4 "solute carrier family 24 (sodium/potassium/calcium exchanger), member 4" 0 0.03 0-0.22 -2.7 -3-6.7 123041 Q8NFF2

268 0.259 ZNF395 zinc finger protein 395 0 0.01 0-0.34 4 -3-7.5 55893 Q9H8N7

269 0.259 ZFP1 ZFP1 zinc finger protein 0 0.01 0-0.06 2.7 -0.4-5.3 162239 Q6P2D0

270 0.259 CEBPA "CCAAT/enhancer binding protein (C/EBP), alpha" 0 0.23 0-0.96 -1.6 -3-6.6 1050 P49715

271 0.258 OPRM1 "opioid receptor, mu 1" 0 0.02 0-0.26 -2.9 -3-4.5 4988 P35372

272 0.258 HMBOX1 homeobox containing 1 0 0 0-0.03 3 -2.6-6.2 79618 Q6NT76

273 0.258 GPR22 G protein-coupled receptor 22 0 0.01 0-0.1 -2.9 -3-4.9 2845 Q99680

274 0.257 FBXO32 F-box protein 32 0 0.01 0-0.25 2.6 -3-9.2 114907 Q969P5

275 0.257 CCM2 cerebral cavernous malformation 2 0 0.08 0-0.9 5.2 3-7.6 83605 Q9BSQ5

276 0.256 CCR6 chemokine (C-C motif) receptor 6 0 0.02 0-0.18 -2.7 -3-6 1235 P51684

277 0.255 TMEM208 transmembrane protein 208 0 0.24 0-0.91 6 4-7.5 29100 Q9BTX3

278 0.255 NLRP4 "NLR family, pyrin domain containing 4" 0 0.02 0-0.3 -2.7 -3-6 147945 Q96MN2

279 0.255 DBP D site of albumin promoter (albumin D-box) binding protein 0 0.07 0-0.75 2.8 -2.9-6.3 1628 Q10586

280 0.255 CMTM6 CKLF-like MARVEL transmembrane domain containing 6 0 0.07 0-0.63 5.2 1.8-8 54918 Q9NX76

281 0.255 ABCC9 "ATP-binding cassette, sub-family C (CFTR/MRP), member 9" 0 0.02 0-0.2 -2.3 -3-5.7 10060 O60706

282 0.255 ABCB8 "ATP-binding cassette, sub-family B (MDR/TAP), member 8" 1 0.01 0-0.18 4.5 2.2-6.6 11194 Q9NUT2

283 0.254 ZNF382 zinc finger protein 382 0 0.01 0-0.21 0 -3-4.6 84911 Q96SR6

284 0.254 TSC1 tuberous sclerosis 1 0 0.09 0-0.9 3.4 1-5.5 7248 Q92574

285 0.254 CCDC9 coiled-coil domain containing 9 0 0.09 0-0.67 4.2 0.7-7 26093 Q9Y3X0

286 0.254 ANKFY1 ankyrin repeat and FYVE domain containing 1 0 0.07 0-0.92 4 -3-5.8 51479 Q9P2R3

287 0.253 TCF12 transcription factor 12 0 0.02 0-0.89 4.7 -1-8.4 6938 Q99081

288 0.252 ZFP36L2 ZFP36 ring finger protein-like 2 0 0.2 0-1 4.4 0.4-8.6 678 P47974

289 0.252 PRR24 proline rich 24 0 0.11 0-0.73 2.5 -3-5.8 255783 C9JVW0

290 0.252 ECE1 endothelin converting enzyme 1 0 0.05 0-0.48 5.1 -2.6-8.2 1889 P42892

291 0.252 CRYZL1 "crystallin, zeta (quinone reductase)-like 1" 0 0.02 0-0.15 4.5 2.3-6.8 9946 O95825

292 0.251 ZNF304 zinc finger protein 304 0 0.01 0-0.1 1.8 -3-4.3 57343 Q9HCX3

293 0.251 ULBP1 UL16 binding protein 1 0 0.03 0-0.56 -0.3 -3-5.1 80329 Q9BZM6

294 0.251 UBE2D1 ubiquitin-conjugating enzyme E2D 1 0 0.02 0-0.22 3.3 -3-6.2 7321 P51668

295 0.251 LYPLA1 lysophospholipase I 1 0.06 0-0.51 5.9 3.7-9.1 10434 O75608

296 0.251 GNGT1 "guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1" 0 0 0-0.05 -2 -3-7.8 2792 P63211

297 0.250 ZEB2 zinc finger E-box binding homeobox 2 0 0.18 0-1 1 -3-6.8 9839 O60315

298 0.250 TCEA1 "transcription elongation factor A (SII), 1" 0 0.08 0-0.66 6.5 4.1-9.4 6917 P23193

299 0.250 PBK PDZ binding kinase 0 0.02 0-0.24 5.2 -1.5-7.8 55872 Q96KB5

300 0.250 OR1Q1 "olfactory receptor, family 1, subfamily Q, member 1" 0 0.07 0-0.47 -2.9 -3-0.6 158131 Q15612

Rank Corr Symbol Description MitoCarta2.0 CDM meanD CDM range TPM mean TPM range Entrez UniProt

17375 -0.076 TACR1 tachykinin receptor 1 0 0.14 0-0.66 -2.5 -3-5.6 6869 P25103

17376 -0.076 SNUPN snurportin 1 0 0.84 0.14-1 4.4 1.5-7.4 10073 O95149

17377 -0.076 SDSL serine dehydratase-like 1 0.05 0-0.48 2.6 -3-6.7 113675 Q96GA7

17378 -0.076 RPL26L1 ribosomal protein L26-like 1 0 0.28 0.01-0.9 6.4 -0.6-9.2 51121 Q9UNX3

17379 -0.076 PTGER3 prostaglandin E receptor 3 (subtype EP3) 0 0.14 0-0.79 -2.2 -3-7.5 5733 P43115

17380 -0.076 PIGH "phosphatidylinositol glycan anchor biosynthesis, class H" 0 0.36 0.03-0.85 3.9 -3-6.2 5283 Q14442

17381 -0.076 PCSK9 proprotein convertase subtilisin/kexin type 9 0 0.27 0.01-0.82 -0.1 -3-8.1 255738 Q8NBP7

17382 -0.076 DCAF4 DDB1 and CUL4 associated factor 4 0 0.26 0.01-0.91 4 -1.8-6.3 26094 Q8WV16

17383 -0.076 C11orf63 chromosome 11 open reading frame 63 0 0.29 0-0.85 0 -3-4.5 79864 Q6NUN7

17384 -0.076 BRAT1 BRCA1-associated ATM activator 1 0 0.49 0-0.99 4.7 1.8-6.9 221927 Q6PJG6

17385 -0.077 TMEM230 transmembrane protein 230 0 0.13 0-0.79 6.5 4.4-8.8 29058 Q96A57

17386 -0.077 THEGL theg spermatid protein-like 0 0.13 0-0.71 -2.7 -3-2.5 100506564 P0DJG4

17387 -0.077 RBM4 RNA binding motif protein 4 0 0.45 0.02-0.98 7.1 5.1-9.2 5936 Q9BWF3

17388 -0.077 PLEKHM1 "pleckstrin homology domain containing, family M (with RUN domain) member 1" 0 0.2 0.01-0.79 3.6 1.4-6.9 9842 Q9Y4G2

17389 -0.077 MCF2L2 MCF.2 cell line derived transforming sequence-like 2 0 0.08 0-0.57 -0.7 -3-4.5 23101 Q86YR7

17390 -0.077 JPH4 junctophilin 4 0 0.18 0-0.73 -2.3 -3-6.2 84502 Q96JJ6

17391 -0.077 IL17D interleukin 17D 0 0.15 0-0.91 1.8 -3-5.7 53342 Q8TAD2

17392 -0.077 EDC4 enhancer of mRNA decapping 4 0 0.48 0.01-0.98 5.6 2.4-7.4 23644 Q6P2E9

17393 -0.077 CD5 CD5 molecule 0 0.21 0-0.65 -2.6 -3-8.9 921 P06127

17394 -0.078 SLC26A10 "solute carrier family 26, member 10" 0 0.18 0-0.92 0.7 -3-7.3 65012 Q8NG04

17395 -0.078 SCN5A "sodium channel, voltage-gated, type V, alpha subunit" 0 0.06 0-0.4 -1.8 -3-5.2 6331 Q14524

17396 -0.078 RPL18 ribosomal protein L18 0 0.99 0.92-1 10.9 8.8-13.3 6141 Q07020

17397 -0.078 OTOA otoancorin 0 0.02 0-0.23 -2.9 -3-6.2 146183 Q7RTW8

17398 -0.078 KCTD10 potassium channel tetramerization domain containing 10 0 0.46 0-1 4.9 2.4-7.1 83892 Q9H3F6

17399 -0.078 JUN jun proto-oncogene 0 0.27 0-1 5.2 -2.1-9.7 3725 P05412

17400 -0.078 HDAC4 histone deacetylase 4 0 0.17 0-0.89 2.9 -3-6.7 9759 P56524

17401 -0.078 HAAO "3-hydroxyanthranilate 3,4-dioxygenase" 0 0.18 0.01-0.9 -1.4 -3-7.7 23498 P46952

17402 -0.078 COPB2 "coatomer protein complex, subunit beta 2 (beta prime)" 0 0.99 0.71-1 6.7 4.2-8.2 9276 P35606

17403 -0.078 CDK12 cyclin-dependent kinase 12 0 0.37 0.01-0.97 4.6 1.8-8.5 51755 Q9NYV4

17404 -0.078 BRI3 brain protein I3 0 0.14 0-0.82 6.5 2.1-9.9 25798 O95415

17405 -0.078 AGFG2 ArfGAP with FG repeats 2 0 0.14 0.01-0.63 2.9 -0.6-6.8 3268 O95081

17406 -0.078 AAK1 AP2 associated kinase 1 0 0.21 0.01-0.76 2.4 -2.7-5.3 22848 Q2M2I8

17407 -0.079 SYPL2 synaptophysin-like 2 0 0.21 0.01-0.73 -2.1 -3-6.7 284612 Q5VXT5

17408 -0.079 SKP1 S-phase kinase-associated protein 1 0 0.72 0.01-1 8.8 6.1-10.5 6500 P63208

17409 -0.079 REV3L "REV3-like, polymerase (DNA directed), zeta, catalytic subunit" 0 0.7 0.07-0.99 3.1 0.6-6.4 5980 O60673

17410 -0.079 RABL2A "RAB, member of RAS oncogene family-like 2A" 0 0.23 0.02-0.93 2.9 0-5.4 11159 Q9UBK7

17411 -0.079 PSAT1 phosphoserine aminotransferase 1 0 0.4 0.03-0.97 6 -2.1-9.6 29968 Q9Y617

17412 -0.079 NOC2L nucleolar complex associated 2 homolog (S. cerevisiae) 0 0.66 0.07-0.98 6.4 4.4-9.8 26155 Q9Y3T9

17413 -0.079 GINS4 GINS complex subunit 4 (Sld5 homolog) 0 0.93 0.24-1 4 -0.5-7.7 84296 Q9BRT9

17414 -0.079 F3 "coagulation factor III (thromboplastin, tissue factor)" 0 0.09 0-0.64 3.7 -3-11.6 2152 P13726

17415 -0.079 DSPP dentin sialophosphoprotein 0 0.05 0-0.33 -3 -3-5.9 1834 Q9NZW4

17416 -0.079 CPNE6 copine VI (neuronal) 0 0.17 0-0.73 -2.9 -3-7.5 9362 O95741

17417 -0.079 ASNS asparagine synthetase (glutamine-hydrolyzing) 0 0.27 0-0.98 6.1 -1.2-10 440 P08243

17418 -0.080 U2AF1 U2 small nuclear RNA auxiliary factor 1 0 0.98 0.59-1 7.8 5.2-10.6 7307 P0DN76

17419 -0.080 TRAPPC11 trafficking protein particle complex 11 0 0.91 0.25-1 3.7 1.6-5.8 60684 Q7Z392

17420 -0.080 SUOX sulfite oxidase 1 0.18 0-0.69 3.5 -3-7 6821 P51687

17421 -0.080 SEMA3G "sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G" 0 0.12 0-0.58 -1.6 -3-4.3 56920 Q9NS98

17422 -0.080 PRPF4B pre-mRNA processing factor 4B 0 0.36 0.01-0.96 5.1 3-6.9 8899 Q13523

17423 -0.080 PLA2G10 "phospholipase A2, group X" 0 0.89 0.37-1 -2 -3-4.4 8399 O15496

17424 -0.080 PAF1 "Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)" 0 0.86 0.16-1 5.8 3.6-10.4 54623 Q8N7H5

17425 -0.080 NDUFB4 "NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 4, 15kDa" 1 0.64 0.02-1 7.6 4.8-9.3 4710 O95168

17426 -0.080 MRPL1 mitochondrial ribosomal protein L1 1 0.39 0.01-0.96 4.4 2-6.5 65008 Q9BYD6

17427 -0.080 EEF1B2 eukaryotic translation elongation factor 1 beta 2 0 0.76 0.26-0.99 9.5 5.2-11.6 1933 P24534

17428 -0.080 CD58 CD58 molecule 0 0.12 0-0.58 4.2 -3-7.4 965 P19256

17429 -0.080 ADCY4 adenylate cyclase 4 0 0.09 0-0.59 -1.8 -3-6.1 196883 Q8NFM4

17430 -0.081 YWHAZ "tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta" 0 0.27 0-0.96 8.7 5.5-11.1 7534 P63104

17431 -0.081 TOMM22 translocase of outer mitochondrial membrane 22 homolog (yeast) 1 0.97 0.68-1 6.1 4-8.1 56993 Q9NS69

17432 -0.081 SMURF1 SMAD specific E3 ubiquitin protein ligase 1 0 0.14 0-0.84 3.7 1-8.2 57154 Q9HCE7

17433 -0.081 SF3B6 "splicing factor 3b, subunit 6, 14kDa" 0 0.76 0.05-0.99 7.4 4.9-9.6 51639 Q9Y3B4

17434 -0.081 RNF41 ring finger protein 41 0 0.21 0-0.86 4.8 2.5-6.8 10193 Q9H4P4

17435 -0.081 LCE2A late cornified envelope 2A 0 0.22 0-0.73 -2.7 -3-9.1 353139 Q5TA79

17436 -0.081 KCNG1 "potassium voltage-gated channel, subfamily G, member 1" 0 0.2 0-0.74 0.8 -3-8.1 3755 Q9UIX4

17437 -0.081 GIMAP1 "GTPase, IMAP family member 1" 0 0.05 0-0.49 -2.7 -3-5.6 170575 Q8WWP7

17438 -0.081 ATN1 atrophin 1 0 0.16 0-0.86 5.5 -0.3-8.2 1822 P54259

17439 -0.081 AFG3L2 AFG3-like AAA ATPase 2 1 0.89 0.11-1 5.3 2.5-7.2 10939 Q9Y4W6

17440 -0.082 ZDHHC22 "zinc finger, DHHC-type containing 22" 0 0.2 0.01-0.9 -2.4 -3-7.6 283576 Q8N966

17441 -0.082 VKORC1L1 "vitamin K epoxide reductase complex, subunit 1-like 1" 0 0.23 0-0.86 4.2 1.5-6.7 154807 Q8N0U8

17442 -0.082 SP7 Sp7 transcription factor 0 0.12 0-0.57 -2.9 -3-4.7 121340 Q8TDD2

17443 -0.082 SLC6A17 "solute carrier family 6 (neutral amino acid transporter), member 17" 0 0.13 0-0.63 -1.7 -3-6.6 388662 Q9H1V8

17444 -0.082 PYDC1 PYD (pyrin domain) containing 1 0 0.12 0.01-0.63 -2.8 -3-3.3 260434 Q8WXC3

17445 -0.082 NAV1 neuron navigator 1 0 0.13 0-0.81 2.3 -3-6.4 89796 Q8NEY1

17446 -0.082 MIB1 mindbomb E3 ubiquitin protein ligase 1 0 0.22 0-1 3.6 0.3-6.6 57534 Q86YT6

17447 -0.082 GTF2F1 "general transcription factor IIF, polypeptide 1, 74kDa" 0 0.4 0-0.93 5.9 3.2-7.8 2962 P35269

17448 -0.082 FKBP8 "FK506 binding protein 8, 38kDa" 1 0.19 0-0.69 7.1 5.1-8.9 23770 Q14318

17449 -0.082 FASN fatty acid synthase 1 0.24 0-1 7.2 3.9-11.3 2194 P49327

17450 -0.082 DPM3 dolichyl-phosphate mannosyltransferase polypeptide 3 0 0.3 0-0.95 6.2 2.8-9.7 54344 Q9P2X0

17451 -0.083 TICRR TOPBP1-interacting checkpoint and replication regulator 0 0.95 0.62-1 3 -0.7-5.4 90381 Q7Z2Z1

17452 -0.083 SOWAHC sosondowah ankyrin repeat domain family member C 0 0.15 0-0.67 1.9 -3-6.7 65124 Q53LP3

17453 -0.083 POU3F3 POU class 3 homeobox 3 0 0.12 0-0.73 -2.2 -3-6 5455 P20264

17454 -0.083 MTRF1L mitochondrial translational release factor 1-like 1 0.28 0-0.98 3.7 1-6 54516 Q9UGC7

17455 -0.083 MRPL51 mitochondrial ribosomal protein L51 1 0.44 0.01-0.97 7.4 4.6-9.5 51258 Q4U2R6

17456 -0.083 LMNB1 lamin B1 0 0.15 0-0.81 6.4 1.4-8.6 4001 P20700

17457 -0.083 EVA1C eva-1 homolog C (C. elegans) 0 0.14 0-0.62 0.7 -3-7 59271 P58658

17458 -0.083 EFTUD1 elongation factor Tu GTP binding domain containing 1 0 0.82 0.25-1 3.5 0.5-5.6 79631 Q7Z2Z2

17459 -0.083 DGKA "diacylglycerol kinase, alpha 80kDa" 0 0.13 0-0.72 4.3 -2.7-8.6 1606 P23743

17460 -0.083 C1orf86 chromosome 1 open reading frame 86 0 0.33 0.01-0.93 5.2 -0.3-8.3 199990 Q6NZ36

17461 -0.083 ARMC5 armadillo repeat containing 5 0 0.41 0.01-0.99 2.6 0.1-5.6 79798 Q96C12

17462 -0.084 RAP1A "RAP1A, member of RAS oncogene family" 0 0.18 0-0.65 5.6 3-8.4 5906 P62834

17463 -0.084 KCNJ9 "potassium inwardly-rectifying channel, subfamily J, member 9" 0 0.14 0-0.9 -2.9 -3-4.2 3765 Q92806

17464 -0.084 IL31 interleukin 31 0 0.11 0-0.49 -3 -3-2.6 386653 Q6EBC2

17465 -0.085 XYLT2 xylosyltransferase II 0 0.39 0-0.99 4 0.8-6.7 64132 Q9H1B5

17466 -0.085 RASEF RAS and EF-hand domain containing 0 0.07 0-0.58 0.4 -3-6.8 158158 Q8IZ41

17467 -0.085 NDUFAB1 "NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1, 8kDa" 1 0.78 0.1-1 7.2 4.6-9 4706 O14561

17468 -0.085 MYBPHL myosin binding protein H-like 0 0.21 0-0.74 -2.6 -3-7.2 343263 A2RUH7

17469 -0.085 COPS3 COP9 signalosome subunit 3 0 0.93 0.26-1 6.4 4.4-9.7 8533 Q9UNS2

17470 -0.085 COPA "coatomer protein complex, subunit alpha" 0 0.99 0.78-1 6.6 3.2-9.4 1314 P53621

17471 -0.085 ACOT12 acyl-CoA thioesterase 12 0 0.39 0.01-0.88 -2.8 -3-6 134526 Q8WYK0

17472 -0.086 SETD1A SET domain containing 1A 0 0.88 0.25-1 3.3 -0.2-5.5 9739 O15047

17473 -0.086 REXO2 RNA exonuclease 2 1 0.41 0.01-1 6.5 2.9-8.8 25996 Q9Y3B8

17474 -0.086 PPP1R14B "protein phosphatase 1, regulatory (inhibitor) subunit 14B" 0 0.3 0.01-0.93 7.7 5.3-10 26472 Q96C90

17475 -0.086 NR0B2 "nuclear receptor subfamily 0, group B, member 2" 0 0.25 0-0.83 -2.4 -3-8.3 8431 Q15466

17476 -0.086 METTL7A methyltransferase like 7A 0 0.33 0-0.83 1.7 -3-8.6 25840 Q9H8H3

17477 -0.086 IMPDH1 IMP (inosine 5'-monophosphate) dehydrogenase 1 0 0.24 0-0.84 5.5 -3-8.7 3614 P20839

17478 -0.086 GPR45 G protein-coupled receptor 45 0 0.17 0.01-0.75 -2.7 -3-2.6 11250 Q9Y5Y3

17479 -0.086 ECT2L epithelial cell transforming sequence 2 oncogene-like 0 0.31 0-0.87 -2.9 -3-1.7 345930 Q008S8

17480 -0.086 C5orf30 chromosome 5 open reading frame 30 0 0.19 0-0.8 3.4 -3-6.6 90355 Q96GV9

17481 -0.086 AK4 adenylate kinase 4 1 0.16 0-0.77 3.5 -3-7.5 205 P27144

17482 -0.087 TTK TTK protein kinase 0 0.83 0.13-1 4.2 -0.1-6.7 7272 P33981

17483 -0.087 TFDP1 transcription factor Dp-1 0 0.59 0.03-0.99 6.6 -1.6-9.8 7027 Q14186

17484 -0.087 PNRC2 proline-rich nuclear receptor coactivator 2 0 0.23 0-0.87 6.1 3.5-8.2 55629 Q9NPJ4

17485 -0.087 ATP5F1 "ATP synthase, H+ transporting, mitochondrial Fo complex, subunit B1" 1 0.48 0.02-1 7.9 5.3-9.7 515 P24539

17486 -0.087 ALG6 "ALG6, alpha-1,3-glucosyltransferase" 0 0.22 0-0.89 3.2 1.2-5.5 29929 Q9Y672

17487 -0.088 SLC2A1 "solute carrier family 2 (facilitated glucose transporter), member 1" 0 0.41 0-1 6.2 1.6-11.3 6513 P11166

17488 -0.088 NACA nascent polypeptide-associated complex alpha subunit 0 0.98 0.77-1 10.5 8.5-12.5 4666 E9PAV3

17489 -0.088 DNM1L dynamin 1-like 1 0.7 0.02-1 5.6 3.4-8.8 10059 O00429

17490 -0.088 BHLHA15 "basic helix-loop-helix family, member a15" 0 0.26 0.01-0.8 -0.8 -3-6.5 168620 Q7RTS1

17491 -0.089 WDR26 WD repeat domain 26 0 0.54 0.01-0.99 5.1 2.4-7.7 80232 Q9H7D7

17492 -0.089 VHL "von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase" 0 0.88 0.02-1 4.9 -3-7.6 7428 P40337

17493 -0.089 SNW1 SNW domain containing 1 0 0.98 0.71-1 6.1 3.5-7.5 22938 Q13573

17494 -0.089 OVOL2 ovo-like zinc finger 2 0 0.31 0-0.91 -0.2 -3-5.8 58495 Q9BRP0

17495 -0.089 GPR61 G protein-coupled receptor 61 0 0.39 0.02-0.93 -1.9 -3-1.8 83873 Q9BZJ8

17496 -0.089 EXT2 exostosin glycosyltransferase 2 0 0.25 0-0.97 5.5 2.2-7.9 2132 Q93063

17497 -0.089 CRK v-crk avian sarcoma virus CT10 oncogene homolog 0 0.18 0-0.98 4.8 1.4-7.6 1398 P46108

17498 -0.089 ATP6V1C1 "ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1" 0 0.69 0.01-1 5 2.1-7.7 528 P21283

17499 -0.089 ATF7 activating transcription factor 7 0 0.08 0-0.67 3.9 1.7-6 11016 P17544

17500 -0.090 ZBTB7B zinc finger and BTB domain containing 7B 0 0.19 0-0.89 4.2 -3-7.8 51043 O15156

17501 -0.090 TSSK3 testis-specific serine kinase 3 0 0.31 0.01-0.88 0 -3-3.7 81629 Q96PN8

17502 -0.090 SLC5A9 "solute carrier family 5 (sodium/sugar cotransporter), member 9" 0 0.1 0-0.6 -2.5 -3-4.8 200010 Q2M3M2

17503 -0.090 LRRC71 leucine rich repeat containing 71 0 0.11 0-0.64 -2.6 -3-3.3 149499 Q8N4P6

17504 -0.090 KIAA1045 KIAA1045 0 0.09 0-0.85 -2.8 -3-5.8 23349 Q9UPV7

17505 -0.090 HOXC6 homeobox C6 0 0.14 0.01-0.79 1 -3-7.1 3223 P09630

17506 -0.090 HMGN2 high mobility group nucleosomal binding domain 2 0 0.72 0.02-0.96 9.5 6.8-12.1 3151 P05204

17507 -0.090 FAM183A "family with sequence similarity 183, member A" 0 0.18 0-0.69 -1.5 -3-3.8 440585 A6NL82

17508 -0.090 ELP6 elongator acetyltransferase complex subunit 6 0 0.95 0.49-1 5.2 2.6-6.7 54859 Q0PNE2

17509 -0.091 PNISR PNN-interacting serine/arginine-rich protein 0 0.41 0-0.95 6.2 2.3-8.6 25957 Q8TF01

17510 -0.091 OPA1 optic atrophy 1 (autosomal dominant) 1 0.44 0.01-0.98 5.3 2.6-7.4 4976 O60313

17511 -0.091 LIMS1 LIM and senescent cell antigen-like domains 1 0 0.44 0-0.95 5.4 2.6-8.8 3987 P48059

17512 -0.091 ITGB5 "integrin, beta 5" 0 0.36 0-1 5.3 -3-10.6 3693 P18084

17513 -0.091 HDAC7 histone deacetylase 7 0 0.15 0-0.96 5 -3-8.4 51564 Q8WUI4

17514 -0.091 DDX5 DEAD (Asp-Glu-Ala-Asp) box helicase 5 0 0.58 0.02-1 8.6 6.8-11.2 1655 P17844

17515 -0.091 CCDC78 coiled-coil domain containing 78 0 0.37 0.01-0.84 2.1 -3-6.7 124093 A2IDD5

17516 -0.092 TRNP1 TMF1-regulated nuclear protein 1 0 0.36 0-0.91 2.2 -3-8.3 388610 Q6NT89

17517 -0.092 NUF2 "NUF2, NDC80 kinetochore complex component" 0 0.96 0.25-1 5.1 0.7-7.8 83540 Q9BZD4

17518 -0.092 GRB2 growth factor receptor-bound protein 2 0 0.77 0.01-1 5.9 3.4-8.1 2885 P62993

17519 -0.092 DMRTA2 DMRT-like family A2 0 0.34 0-0.79 -1.9 -3-5.1 63950 Q96SC8

17520 -0.092 CHTF8 "CTF8, chromosome transmission fidelity factor 8 homolog (S. cerevisiae)" 0 0.67 0.02-1 6.3 4.2-7.6 54921 P0CG12

17521 -0.093 SUGT1 "SGT1, suppressor of G2 allele of SKP1 (S. cerevisiae)" 0 0.64 0.03-1 5.6 3.3-7.8 10910 Q9Y2Z0

17522 -0.093 SOX10 SRY (sex determining region Y)-box 10 0 0.39 0.02-1 -2.3 -3-8.6 6663 P56693

17523 -0.093 SLC22A25 "solute carrier family 22, member 25" 0 0.27 0.02-0.73 -3 -3--0.2 387601 Q6T423

17524 -0.093 HK2 hexokinase 2 1 0.2 0-0.97 4.2 -3-7.2 3099 P52789

17525 -0.093 COL9A1 "collagen, type IX, alpha 1" 0 0.09 0-0.61 -2.7 -3-5.4 1297 P20849

17526 -0.093 CCT5 "chaperonin containing TCP1, subunit 5 (epsilon)" 0 0.89 0.2-1 8.8 6.5-10.9 22948 P48643

17527 -0.093 BCAN brevican 0 0.31 0.01-0.86 -2.1 -3-6.4 63827 Q96GW7

17528 -0.094 YARS tyrosyl-tRNA synthetase 0 1 0.82-1 6.6 4.3-9 8565 P54577

17529 -0.094 WWTR1 WW domain containing transcription regulator 1 0 0.46 0-0.99 3.6 -3-9.1 25937 Q9GZV5

17530 -0.094 MXRA7 matrix-remodelling associated 7 0 0.33 0.01-0.82 4.8 -3-9 439921 P84157

17531 -0.094 CLPTM1 cleft lip and palate associated transmembrane protein 1 0 0.14 0-0.71 5.9 2.3-8.4 1209 O96005

17532 -0.095 TPBGL trophoblast glycoprotein-like 0 0.21 0-0.87 -2.5 -3-3.7 100507050 P0DKB5

17533 -0.095 PRKACG "protein kinase, cAMP-dependent, catalytic, gamma" 0 0.12 0-0.66 -3 -3--2.1 5568 P22612

17534 -0.095 POLR3B polymerase (RNA) III (DNA directed) polypeptide B 0 0.98 0.66-1 2.5 -0.1-4.5 55703 Q9NW08

17535 -0.095 MGA "MGA, MAX dimerization protein" 0 0.22 0-0.93 2.8 -3-5.2 23269 Q8IWI9

17536 -0.095 ELMO2 engulfment and cell motility 2 0 0.35 0-0.99 4.5 1.8-6.6 63916 Q96JJ3

17537 -0.095 CHAF1A "chromatin assembly factor 1, subunit A (p150)" 0 0.97 0.6-1 5 1.8-7.1 10036 Q13111

17538 -0.095 C7orf55-LUC7L2 C7orf55-LUC7L2 readthrough 0 0.91 0.52-1 4.2 -3-6.5 100996928 A0A0A6YYJ8

17539 -0.096 NCL nucleolin 0 0.76 0.18-1 8.7 6.1-10.2 4691 P19338

17540 -0.096 DPM2 "dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit" 0 0.49 0.02-0.98 5.6 3.8-7.3 8818 O94777

17541 -0.096 ASF1B anti-silencing function 1B histone chaperone 0 0.47 0.04-1 5.6 0.8-8.3 55723 Q9NVP2

17542 -0.097 TNNT2 troponin T type 2 (cardiac) 0 0.65 0.03-0.97 -1.1 -3-9.7 7139 P45379

17543 -0.097 TMEM165 transmembrane protein 165 0 0.21 0-0.96 5.8 3.4-9.6 55858 Q9HC07

17544 -0.097 SPDYE2 speedy/RINGO cell cycle regulator family member E2 0 0.56 0.04-0.98 0.1 -3-3.7 441273 Q495Y8

17545 -0.097 RINT1 RAD50 interactor 1 0 0.58 0.03-0.96 4.1 1.9-6 60561 Q6NUQ1

17546 -0.097 CLPS "colipase, pancreatic" 0 0.31 0-0.8 -3 -3-2.5 1208 P04118

17547 -0.097 ANAPC10 anaphase promoting complex subunit 10 0 0.51 0-0.97 4.2 2.5-6 10393 Q9UM13

17548 -0.097 ADAT3 "adenosine deaminase, tRNA-specific 3" 0 0.45 0-0.97 1.7 -3-4.9 113179 Q96EY9

17549 -0.098 ZNF322 zinc finger protein 322 0 0.08 0-0.49 3.1 -3-6.9 79692 Q6U7Q0

17550 -0.098 VCP valosin containing protein 0 1 0.86-1 7.4 4.6-10.2 7415 P55072

17551 -0.098 TUBGCP3 "tubulin, gamma complex associated protein 3" 0 0.87 0.02-1 4.3 2-7.3 10426 Q96CW5

17552 -0.099 TRAPPC3 trafficking protein particle complex 3 0 0.98 0.31-1 6.1 3.9-7.7 27095 O43617

17553 -0.099 OST4 oligosaccharyltransferase 4 homolog (S. cerevisiae) 0 0.44 0-0.98 8 4.8-9.7 100128731 P0C6T2

17554 -0.099 HOXD4 homeobox D4 0 0.09 0-0.72 -1.2 -3-4.5 3233 P09016

17555 -0.099 FEM1A fem-1 homolog a (C. elegans) 0 0.26 0-0.91 2.6 -1.4-4.7 55527 Q9BSK4

17556 -0.099 EIF3CL "eukaryotic translation initiation factor 3, subunit C-like" 0 0.99 0.81-1 6.1 3.6-8.1 728689 B5ME19

17557 -0.099 CHMP7 charged multivesicular body protein 7 0 0.72 0.03-1 4.6 2.1-6.6 91782 Q8WUX9

17558 -0.100 KLHL40 kelch-like family member 40 0 0.22 0-0.76 -3 -3-2.4 131377 Q2TBA0

17559 -0.100 DPPA2 developmental pluripotency associated 2 0 0.34 0.04-0.83 -2.7 -3-7 151871 Q7Z7J5

17560 -0.100 CYP4B1 "cytochrome P450, family 4, subfamily B, polypeptide 1" 0 0.11 0-0.52 -2.1 -3-8.5 1580 P13584

17561 -0.100 CHP1 calcineurin-like EF-hand protein 1 0 0.22 0-0.97 5.3 2.6-8 11261 Q99653

17562 -0.100 CDC40 cell division cycle 40 0 0.83 0.05-1 3.6 1.3-5.8 51362 O60508

17563 -0.100 BCAR1 breast cancer anti-estrogen resistance 1 0 0.69 0.02-1 4.4 -3-8.2 9564 P56945

17564 -0.101 TICAM2 toll-like receptor adaptor molecule 2 0 0.83 0.37-1 0.1 -3-4.8 353376

17565 -0.101 NPM1 "nucleophosmin (nucleolar phosphoprotein B23, numatrin)" 0 0.58 0-0.98 11.2 7.4-13 4869 P06748

17566 -0.101 MRPL50 mitochondrial ribosomal protein L50 1 0.48 0.01-0.97 4.3 2-6.1 54534 Q8N5N7

17567 -0.101 LSM6 "LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae)" 0 0.86 0.08-1 6.2 4-8.7 11157 P62312

17568 -0.101 GPI glucose-6-phosphate isomerase 1 0.42 0-0.99 8 5.6-10.5 2821 P06744

17569 -0.101 DPPA3 developmental pluripotency associated 3 0 0.32 0.01-0.85 -3 -3-3.9 359787 Q6W0C5

17570 -0.102 TUBA1C "tubulin, alpha 1c" 0 0.75 0.02-1 8.6 3-10.6 84790 Q9BQE3

17571 -0.102 TMA7 translation machinery associated 7 homolog (S. cerevisiae) 0 0.18 0-0.76 8.3 5.2-10.7 51372 Q9Y2S6

17572 -0.102 PPP1R12A "protein phosphatase 1, regulatory subunit 12A" 0 0.87 0-1 4.8 1.6-7.7 4659 O14974

17573 -0.102 GPR137C G protein-coupled receptor 137C 0 0.22 0-0.9 -0.1 -3-5.4 283554 Q8N3F9

17574 -0.102 APC adenomatous polyposis coli 0 0.41 0-0.98 2.6 -0.5-4.8 324 P25054

17575 -0.103 ZNF720 zinc finger protein 720 0 0.89 0.28-0.99 3.6 -3-7.7 124411 Q7Z2F6

17576 -0.103 SETD8 SET domain containing (lysine methyltransferase) 8 0 0.31 0-0.86 5.5 3.2-7.5 387893 Q9NQR1

17577 -0.103 RCSD1 RCSD domain containing 1 0 0.08 0-0.44 -0.9 -3-8.8 92241 Q6JBY9

17578 -0.103 PRSS50 "protease, serine, 50" 0 0.28 0.01-0.84 -2.6 -3-5.1 29122 Q9UI38

17579 -0.103 PPIL4 peptidylprolyl isomerase (cyclophilin)-like 4 0 0.89 0.37-1 4.3 1.2-6.5 85313 Q8WUA2

17580 -0.104 RNF181 ring finger protein 181 0 0.23 0.01-0.87 7.2 5.2-9.1 51255 Q9P0P0

17581 -0.104 CA5A "carbonic anhydrase VA, mitochondrial" 1 0.33 0-0.82 -2.9 -3-7.6 763 P35218

17582 -0.105 FMO1 flavin containing monooxygenase 1 0 0.29 0-0.83 -2.9 -3-4.6 2326 Q01740

17583 -0.106 RC3H1 ring finger and CCCH-type domains 1 0 0.17 0-0.8 2.1 0.1-4.6 149041 Q5TC82

17584 -0.106 DDX23 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 0 0.9 0.13-1 6.3 3.3-9 9416 Q9BUQ8

17585 -0.107 GNG13 "guanine nucleotide binding protein (G protein), gamma 13" 0 0.27 0.01-0.78 -1.6 -3-7.7 51764 Q9P2W3

17586 -0.108 TBP TATA box binding protein 0 0.49 0.01-0.98 4 1.3-5.8 6908 P20226

17587 -0.108 PFDN5 prefoldin subunit 5 0 0.62 0.05-0.98 8.9 6.9-11.4 5204 Q99471

17588 -0.108 C12orf56 chromosome 12 open reading frame 56 0 0.29 0.01-0.9 -1.4 -3-4.9 115749 Q8IXR9

17589 -0.109 RPS15 ribosomal protein S15 0 0.92 0.6-1 10.2 7.2-12.3 6209 P62841

17590 -0.109 ENTHD2 ENTH domain containing 2 0 0.42 0.03-0.92 4 1.4-6.1 146705 Q96N21

17591 -0.110 USPL1 ubiquitin specific peptidase like 1 0 0.88 0.1-1 3.1 0.3-5.8 10208 Q5W0Q7

17592 -0.110 TCTE1 t-complex-associated-testis-expressed 1 0 0.12 0-0.88 -2.8 -3-4.5 202500 Q5JU00

17593 -0.110 MMAB methylmalonic aciduria (cobalamin deficiency) cblB type 1 0.19 0-0.64 5 2.2-7.3 326625 Q96EY8

17594 -0.110 ISCU iron-sulfur cluster assembly enzyme 1 0.97 0.52-1 6.3 4.7-8.6 23479 Q9H1K1

17595 -0.111 SLBP stem-loop binding protein 0 0.46 0.02-0.94 6.2 3.7-8.6 7884 Q14493

17596 -0.112 EIF2B3 "eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa" 0 0.97 0.67-1 4.9 2.5-7.1 8891 Q9NR50

17597 -0.113 SUPV3L1 "suppressor of var1, 3-like 1 (S. cerevisiae)" 1 0.92 0.4-1 4.8 3.3-6.8 6832 Q8IYB8

17598 -0.113 SNRPC small nuclear ribonucleoprotein polypeptide C 0 0.96 0.6-1 7.7 5.6-9.7 6631 P09234

17599 -0.113 FOXD4L6 forkhead box D4-like 6 0 0.5 0.04-0.91 653404 Q3SYB3

17600 -0.114 TOMM40 translocase of outer mitochondrial membrane 40 homolog (yeast) 1 0.95 0.64-1 6.3 3.9-8.9 10452 O96008

17601 -0.114 LENG8 leukocyte receptor cluster (LRC) member 8 0 0.74 0.08-0.98 6.7 3.6-9.4 114823 Q96PV6

17602 -0.114 FAM73B "family with sequence similarity 73, member B" 0 0.2 0-0.69 4 0.9-6.2 84895 Q7L4E1

17603 -0.115 RGPD2 RANBP2-like and GRIP domain containing 2 0 0.27 0.01-0.86 -0.5 -3-6.4 729857 P0DJD1

17604 -0.115 NUFIP1 nuclear fragile X mental retardation protein interacting protein 1 0 0.37 0.01-0.94 2.3 0.1-4.3 26747 Q9UHK0

17605 -0.115 ILK integrin-linked kinase 0 0.47 0-0.99 6.3 3.9-8.5 3611 Q13418

17606 -0.116 TMEM242 transmembrane protein 242 0 0.26 0.01-0.93 2.5 0.5-4.4 729515 Q9NWH2

17607 -0.116 CDV3 CDV3 homolog (mouse) 0 0.2 0-0.64 6.6 1.7-9.9 55573 Q9UKY7

17608 -0.117 OSTC oligosaccharyltransferase complex subunit (non-catalytic) 0 0.8 0.27-0.99 6.9 5-8.8 58505 Q9NRP0

17609 -0.118 RTKN rhotekin 0 0.24 0.01-0.83 3.9 -3-7.4 6242 Q9BST9

17610 -0.118 DCAF6 DDB1 and CUL4 associated factor 6 0 0.31 0.01-0.89 5.1 3.3-7.3 55827 Q58WW2

17611 -0.120 ERH enhancer of rudimentary homolog (Drosophila) 0 0.98 0.67-1 7.8 5.7-9.4 2079 P84090

17612 -0.121 THAP1 "THAP domain containing, apoptosis associated protein 1" 0 0.96 0.26-1 2.8 0.6-4.5 55145 Q9NVV9

17613 -0.121 STX18 syntaxin 18 0 0.79 0.12-1 4.4 2.2-7.6 53407 Q9P2W9

17614 -0.121 KCNA10 "potassium voltage-gated channel, shaker-related subfamily, member 10" 0 0.39 0.01-0.86 -3 -3-2.2 3744 Q16322

17615 -0.121 DYNLRB1 "dynein, light chain, roadblock-type 1" 0 0.99 0.63-1 7.9 5.7-12.3 83658 Q9NP97

17616 -0.121 CHCHD5 coiled-coil-helix-coiled-coil-helix domain containing 5 1 0.21 0-0.84 4.6 -3-7.1 84269 Q9BSY4

17617 -0.122 RPS18 ribosomal protein S18 1 0.95 0.6-1 11.9 8.9-14.1 6222 P62269

17618 -0.122 RABGGTB "Rab geranylgeranyltransferase, beta subunit" 0 0.97 0.46-1 6.7 4.5-8.5 5876 P53611

17619 -0.122 PSMB5 "proteasome (prosome, macropain) subunit, beta type, 5" 0 0.96 0.31-1 7.3 4.1-9.4 5693 P28074

17620 -0.122 CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like 0 0.72 0.01-1 4.9 2.8-9.5 1399 P46109

17621 -0.123 YPEL5 yippee-like 5 (Drosophila) 0 0.73 0-1 4.8 -0.1-8.5 51646 P62699

17622 -0.123 LARP4 "La ribonucleoprotein domain family, member 4" 0 0.3 0-0.87 4.6 1.6-6.5 113251 Q71RC2

17623 -0.124 NUPL1 nucleoporin like 1 0 0.38 0.01-0.95 4.8 2.3-6.9 9818 Q9BVL2

17624 -0.125 SLC25A28 "solute carrier family 25 (mitochondrial iron transporter), member 28" 1 0.32 0-0.99 4.6 2.8-7.1 81894 Q96A46

17625 -0.126 WDR83 WD repeat domain 83 0 0.44 0-0.98 3.7 1.9-5.7 84292 Q9BRX9

17626 -0.127 ITGAV "integrin, alpha V" 0 0.46 0-1 4.5 -3-8.5 3685 P06756

17627 -0.127 HSPD1 heat shock 60kDa protein 1 (chaperonin) 1 0.94 0.43-1 8.8 6.3-10.7 3329 P10809

17628 -0.128 FERMT2 fermitin family member 2 0 0.6 0.01-1 3.3 -3-8.2 10979 Q96AC1

17629 -0.128 CCND1 cyclin D1 0 0.78 0.08-1 5.8 -2.6-12.3 595 P24385

17630 -0.129 FBLIM1 filamin binding LIM protein 1 0 0.48 0.03-0.91 2.7 -3-7.6 54751 Q8WUP2

17631 -0.130 PPP1R15B "protein phosphatase 1, regulatory subunit 15B" 0 0.77 0.03-1 4.6 2-8.2 84919

17632 -0.132 UQCRH ubiquinol-cytochrome c reductase hinge protein 1 0.87 0.12-0.99 9.1 0.7-11.8 7388 P07919

17633 -0.133 TLN1 talin 1 0 0.84 0.24-1 6.4 2.1-9.9 7094 Q9Y490

17634 -0.136 RPL41 ribosomal protein L41 0 0.68 0.03-0.98 11.8 8.1-13.8 6171 P62945

17635 -0.136 PRPF4 pre-mRNA processing factor 4 0 0.9 0.22-1 4.9 2.2-6.8 9128 O43172

17636 -0.136 GTF2E2 "general transcription factor IIE, polypeptide 2, beta 34kDa" 0 0.83 0.15-1 4.6 2.4-6.6 2961 P29084

17637 -0.141 RCL1 RNA terminal phosphate cyclase-like 1 0 0.81 0.05-1 3.6 1-9.4 10171 Q9Y2P8

17638 -0.142 PTK2 protein tyrosine kinase 2 0 0.62 0-1 5.4 -3-8 5747 Q05397

17639 -0.143 FAM133B "family with sequence similarity 133, member B" 0 0.55 0.05-0.98 4.7 1.3-9.8 257415 Q5BKY9

17640 -0.144 HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2) 0 0.88 0.34-1 9.3 7.4-10.4 3183 P07910

17641 -0.145 LSM4 "LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae)" 0 0.85 0.15-1 7.5 5.2-9.2 25804 Q9Y4Z0

17642 -0.146 PPP1R10 "protein phosphatase 1, regulatory subunit 10" 0 0.93 0.4-1 4.7 2.5-6.7 5514 Q96QC0

17643 -0.146 DENR density-regulated protein 0 0.8 0.01-1 5.6 3.8-7.6 8562 O43583

17644 -0.152 TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) 1 0.56 0-0.99 3.4 0.7-5.3 29928 Q9Y584

17645 -0.155 RBM42 RNA binding motif protein 42 0 0.71 0.01-0.99 6.2 3.1-8.6 79171 Q9BTD8

17646 -0.155 RAC1 "ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)" 0 0.65 0-1 7.7 4.4-9.9 5879 P63000

17647 -0.155 AASDHPPT aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0 0.5 0.01-0.98 4.7 2.3-8.8 60496 Q9NRN7

17648 -0.157 C19orf52 chromosome 19 open reading frame 52 1 0.61 0.01-0.99 3.9 2.2-6.7 90580 Q9BSF4

17649 -0.160 STARD7 StAR-related lipid transfer (START) domain containing 7 1 0.52 0-1 6.4 4.3-8 56910 Q9NQZ5

17650 -0.160 PMPCA peptidase (mitochondrial processing) alpha 1 0.98 0.75-1 5.8 3.6-8.4 23203 Q10713

17651 -0.160 DHX16 DEAH (Asp-Glu-Ala-His) box polypeptide 16 0 0.78 0.06-0.98 5.3 3.6-7.3 8449 O60231

17652 -0.164 RPL7L1 ribosomal protein L7-like 1 0 0.73 0.06-0.99 6.3 3.9-9.2 285855 Q6DKI1

17653 -0.165 SRP54 signal recognition particle 54kDa 0 0.97 0.52-1 5.8 3.2-9.2 6729 P61011

17654 -0.166 MTOR mechanistic target of rapamycin (serine/threonine kinase) 0 0.97 0.61-1 4.7 2.4-7.4 2475 P42345

17655 -0.168 ABCE1 "ATP-binding cassette, sub-family E (OABP), member 1" 0 0.9 0.18-1 5.7 3.4-7.6 6059 P61221

17656 -0.170 UBC ubiquitin C 0 0.71 0-1 9.4 7-11.4 7316 P0CG48

17657 -0.171 WBSCR22 Williams Beuren syndrome chromosome region 22 0 0.98 0.72-1 7.2 4.9-9.3 114049 O43709

17658 -0.172 NUP62 nucleoporin 62kDa 0 0.84 0.07-1 6.1 3.7-8.2 23636 P37198

17659 -0.173 NUP54 nucleoporin 54kDa 0 0.85 0.13-1 4.8 2.7-6.3 53371 Q7Z3B4

17660 -0.175 SF1 splicing factor 1 0 1 0.89-1 7.5 4.4-9.1 7536 Q15637

17661 -0.177 PPP1R2 "protein phosphatase 1, regulatory (inhibitor) subunit 2" 0 0.92 0.19-1 4.7 2.7-7.5 5504 P41236

17662 -0.184 NCKAP1 NCK-associated protein 1 0 0.64 0-0.99 5.2 -3-8 10787 Q9Y2A7

17663 -0.185 ANAPC1 anaphase promoting complex subunit 1 0 0.87 0.02-1 4.5 2.3-6.5 64682 Q9H1A4

17664 -0.200 NARS asparaginyl-tRNA synthetase 0 0.99 0.67-1 7.2 4.3-9.9 4677 O43776

17665 -0.205 POLA2 "polymerase (DNA directed), alpha 2, accessory subunit" 0 0.91 0.14-1 4.7 1.2-6.4 23649 Q14181

17666 -0.210 POLR1B "polymerase (RNA) I polypeptide B, 128kDa" 0 0.92 0.1-1 4.2 1.5-6.4 84172 Q9H9Y6

17667 -0.212 SMG6 SMG6 nonsense mediated mRNA decay factor 0 0.9 0.22-1 3.8 1-7.5 23293 Q86US8

17668 -0.217 ST20-MTHFS ST20-MTHFS readthrough 0 0.71 0.07-0.95 1.1 -3-4 100528021 A0A0A6YYL1

17669 -0.221 NOP56 NOP56 ribonucleoprotein 0 0.97 0.55-1 8.4 5.4-10.3 10528 O00567

17670 -0.243 DDX18 DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 0 0.87 0.02-1 5.7 3.5-7.5 8886 Q9NVP1

17671 -0.251 KCMF1 potassium channel modulatory factor 1 0 0.82 0.01-1 5.7 2.7-7.9 56888 Q9P0J7

17672 -0.342 RPS17 ribosomal protein S17 0 0.97 0.56-1 10.8 4.5-12.6 6218 P08708

17673 -0.369 ARCN1 archain 1 0 0.95 0.21-1 6.5 4-9.4 372 P48444

17674 -0.392 UBR4 ubiquitin protein ligase E3 component n-recognin 4 0 0.92 0.01-1 6.4 0-9.1 23352 Q5T4S7