Human synonyms | SCD | FADS5|MSTP008|SCD1|SCDOS|hSCD1 | GeneID:6319 | ENSG00000099194 | O00767 |
Mouse ortholog | Scd2 | Mir5114|Scd-|Scd-2|mir-5114|swty | GeneID:20250 | ENSMUSG00000025203 | P13011 |
Tissue Atlas Coexpression | human GTEx RNA, mouse GNFv3 RNA, mouse protein |
CCLE cell lines | CRISPR-codependency, RNA-seq coexpression, RNA-microarray, CRISPR-vs-RNA-seq |
Sequence Alignment (MitoCarta only) | all_BBH, selected_BBH |
In MitoCarta3.0? | 0 |
Evidence | Rickettsial homolog, mito protein domain |
MitoPathway | |
Sub-Mito Localization | |
MS/MS tissues | |
MitoCarta2.0 FDR | 0.578 |
MitoCarta2.0 Training | Tnon_mito |
TargetP_v1 MTS Confidence | |
MitoDomain | SharedDomain |
Yeast Homolog | NoMitoHomolog |
Rickettsia Homolog | Homolog |
GeneAtlas Coexpression N50  | 2 |
PGC Induction | |
MSMS score | |
MSMS intensity | cerebrum:, cerebellum:, brainstem:, spinalcord:, kidney:, liver:, heart:, muscle:, adipose:, sm_intestine:, lg_intestine:, stomach:, placenta:, testis: |
MSMS unique peps | |
Curator notes |
HPA Main Location (2020) | Endoplasmic reticulum (Enhanced) |
PFAM domains (2022) | 0 |
CRISPR guides |
Glu/Gal Death Screen (2016) | not strongly enriched in Gal/Glu dead cells (fdr=1) |
O2 Screen Summary (2020) | not selectively essential in 1% vs 21% oxygen (fdr=1) |
1%O2_vs_21%O2.day15.score (2020) | 0 |
21%O2.day15_vs_day0.score (2020) | -1.8 |
Chemical Genetics Zscore (To 2019) | DMSO:-9.3 (fdr=0); Met:-4.7 (fdr=0); Pier:-7.3 (fdr=0); Anti:-6.5 (fdr=0); Oligo:-4.6 (fdr=0.0001); AO:-3.7 (fdr=0.0019); EtBr:-6.8 (fdr=0); CAP:-6.4 (fdr=0); |
TMRM Oligo Zscore (unpublished) | -2 |
Species | mRNA | ProteinID | Len (AA) | TargetP v1.0 | TargetP v2.0 | TPpred2 | MitoFates | Mouse Best | TMHMM # Helices | TMHMM Topology |
---|---|---|---|---|---|---|---|---|---|---|
human | NM_005063 | NP_005054 | 359 | no pred (conf=1) | noTP | noMTS (score=0.92) | 4 | i71-93o98-120i217-239o249-271i | ||
mouse | NM_009128 | NP_033154 | 358 | no pred (conf=2) | noTP | noMTS (score=0.83) | 4 | i70-92o102-124i216-235o250-272i |