Human synonyms | ILF3 | CBTF|DRBF|DRBP76|MMP4|MPHOSPH4|MPP4|MPP4110|NF-AT-90|NF110|NF110b|NF90|NF90a|NF90b|NF90c|NF90ctv|NFAR|NFAR-1|NFAR-2|NFAR110|NFAR2|NFAR90|TCP110|TCP80 | GeneID:3609 | ENSG00000129351 | Q12906 |
Mouse ortholog | Ilf3 | MBII-26|MPHOSPH4|NF9|NF90|NFAR | GeneID:16201 | ENSMUSG00000032178 | Q9Z1X4 |
Tissue Atlas Coexpression | human GTEx RNA, mouse GNFv3 RNA, mouse protein |
CCLE cell lines | CRISPR-codependency, RNA-seq coexpression, RNA-microarray, CRISPR-vs-RNA-seq |
Sequence Alignment (MitoCarta only) | all_BBH, selected_BBH |
In MitoCarta3.0? | 0 |
Evidence | mito protein domain |
MitoPathway | |
Sub-Mito Localization | |
MS/MS tissues | largeintestine |
MitoCarta2.0 FDR | 0.573 |
MitoCarta2.0 Training | Tpossible_mito |
TargetP_v1 MTS Confidence | |
MitoDomain | SharedDomain |
Yeast Homolog | NoMitoHomolog |
Rickettsia Homolog | NoHomolog |
GeneAtlas Coexpression N50  | 1 |
PGC Induction | -0.32 |
MSMS score | 0-25ambig |
MSMS intensity | cerebrum:, cerebellum:, brainstem:, spinalcord:, kidney:, liver:, heart:, muscle:, adipose:, sm_intestine:, lg_intestine:7.1, stomach:, placenta:, testis: |
MSMS unique peps | 2 |
Curator notes |
HPA Main Location (2020) | Mitochondria;Nucleoli;Nucleoplasm (Supported) |
PFAM domains (2022) | DZF|dsrm |
CRISPR guides |
Glu/Gal Death Screen (2016) | not strongly enriched in Gal/Glu dead cells (fdr=1) |
O2 Screen Summary (2020) | not selectively essential in 1% vs 21% oxygen (fdr=1) |
1%O2_vs_21%O2.day15.score (2020) | 0.2 |
21%O2.day15_vs_day0.score (2020) | -2.2 |
Chemical Genetics Zscore (To 2019) | DMSO:-5.9 (fdr=0); Met:-3.6 (fdr=0.0026); Pier:-3.4 (fdr=0.0052); EtBr:-2.5 (fdr=0.0789); CAP:-3.8 (fdr=0.0011); |
TMRM Oligo Zscore (unpublished) | -1.1 |
Species | mRNA | ProteinID | Len (AA) | TargetP v1.0 | TargetP v2.0 | TPpred2 | MitoFates | Mouse Best | TMHMM # Helices | TMHMM Topology |
---|---|---|---|---|---|---|---|---|---|---|
mouse | NM_001042708 | NP_001036173 | 716 | MTS (conf=2 len=31) | noTP | noMTS (score=0.84) | 0 | o | ||
mouse | NM_001277321 | NP_001264250 | 908 | MTS (conf=2 len=31) | noTP | noMTS (score=0.84) | 0 | o | ||
mouse | NM_001042709 | NP_001036174 | 703 | no pred (conf=4) | noTP | noMTS (score=0.97) | 0 | o | ||
human | NM_004516 | NP_004507 | 702 | no pred (conf=4) | noTP | noMTS (score=0.97) | 0 | o | ||
human | NM_001137673 | NP_001131145 | 706 | no pred (conf=4) | noTP | noMTS (score=0.97) | 0 | o | ||
mouse | NM_010561 | NP_034691 | 911 | MTS (conf=2 len=31) | noTP | noMTS (score=0.84) | 0 | o | ||
mouse | NM_001277322 | NP_001264251 | 911 | MTS (conf=2 len=31) | noTP | noMTS (score=0.84) | 0 | o | ||
human | NM_017620 | NP_060090 | 898 | no pred (conf=4) | noTP | noMTS (score=0.97) | 0 | o | ||
mouse | NM_001042707 | NP_001036172 | 898 | no pred (conf=4) | noTP | noMTS (score=0.97) | 0 | o | ||
human | NM_012218 | NP_036350 | 894 | no pred (conf=4) | noTP | noMTS (score=0.97) | 0 | o | ||
human | NM_153464 | NP_703194 | 690 | no pred (conf=4) | noTP | noMTS (score=0.97) | 0 | o |