ILF3: interleukin enhancer binding factor 3

All genes, All MitoCarta3.0 genes, FAQ

Human synonymsILF3 | CBTF|DRBF|DRBP76|MMP4|MPHOSPH4|MPP4|MPP4110|NF-AT-90|NF110|NF110b|NF90|NF90a|NF90b|NF90c|NF90ctv|NFAR|NFAR-1|NFAR-2|NFAR110|NFAR2|NFAR90|TCP110|TCP80 | GeneID:3609 | ENSG00000129351 | Q12906
Mouse orthologIlf3 | MBII-26|MPHOSPH4|NF9|NF90|NFAR | GeneID:16201 | ENSMUSG00000032178 | Q9Z1X4

MoothaLab Resources
Tissue Atlas Coexpression human GTEx RNA, mouse GNFv3 RNA, mouse protein
CCLE cell lines CRISPR-codependency, RNA-seq coexpression, RNA-microarray, CRISPR-vs-RNA-seq
Sequence Alignment (MitoCarta only) all_BBH, selected_BBH

MitoCarta3.0
In MitoCarta3.0?0
Evidencemito protein domain
MitoPathway
Sub-Mito Localization
MS/MS tissueslargeintestine
MitoCarta2.0 FDR0.573
MitoCarta2.0 TrainingTpossible_mito
TargetP_v1 MTS Confidence
MitoDomainSharedDomain
Yeast HomologNoMitoHomolog
Rickettsia HomologNoHomolog
GeneAtlas Coexpression N50 1
PGC Induction-0.32
MSMS score0-25ambig
MSMS intensitycerebrum:, cerebellum:, brainstem:, spinalcord:, kidney:, liver:, heart:, muscle:, adipose:, sm_intestine:, lg_intestine:7.1, stomach:, placenta:, testis:
MSMS unique peps2
Curator notes

Miscellaneous features
HPA Main Location (2020)Mitochondria;Nucleoli;Nucleoplasm (Supported)
PFAM domains (2022)DZF|dsrm
CRISPR guides

Mootha Lab CRISPR Screen Results
Glu/Gal Death Screen (2016)not strongly enriched in Gal/Glu dead cells (fdr=1)
O2 Screen Summary (2020)not selectively essential in 1% vs 21% oxygen (fdr=1)
1%O2_vs_21%O2.day15.score (2020)0.2
21%O2.day15_vs_day0.score (2020)-2.2
Chemical Genetics Zscore (To 2019)DMSO:-5.9 (fdr=0); Met:-3.6 (fdr=0.0026); Pier:-3.4 (fdr=0.0052); EtBr:-2.5 (fdr=0.0789); CAP:-3.8 (fdr=0.0011);
TMRM Oligo Zscore (unpublished)-1.1

Refseq Protein Isoforms
Species mRNA ProteinID Len (AA) TargetP v1.0 TargetP v2.0 TPpred2 MitoFates Mouse Best TMHMM # Helices TMHMM Topology
mouseNM_001042708NP_001036173 716MTS (conf=2 len=31)noTPnoMTS (score=0.84)0o
mouseNM_001277321NP_001264250 908MTS (conf=2 len=31)noTPnoMTS (score=0.84)0o
mouseNM_001042709NP_001036174 703no pred (conf=4)noTPnoMTS (score=0.97)0o
humanNM_004516NP_004507 702no pred (conf=4)noTPnoMTS (score=0.97)0o
humanNM_001137673NP_001131145 706no pred (conf=4)noTPnoMTS (score=0.97)0o
mouseNM_010561NP_034691 911MTS (conf=2 len=31)noTPnoMTS (score=0.84)0o
mouseNM_001277322NP_001264251 911MTS (conf=2 len=31)noTPnoMTS (score=0.84)0o
humanNM_017620NP_060090 898no pred (conf=4)noTPnoMTS (score=0.97)0o
mouseNM_001042707NP_001036172 898no pred (conf=4)noTPnoMTS (score=0.97)0o
humanNM_012218NP_036350 894no pred (conf=4)noTPnoMTS (score=0.97)0o
humanNM_153464NP_703194 690no pred (conf=4)noTPnoMTS (score=0.97)0o