FFAR1: free fatty acid receptor 1

All genes, All MitoCarta3.0 genes, FAQ

Human synonymsFFAR1 | FFA1R|GPCR40|GPR40 | GeneID:2864 | ENSG00000126266 | O14842
Mouse orthologFfar1 | Gpr|Gpr40 | GeneID:233081 | ENSMUSG00000044453 | Q76JU9

MoothaLab Resources
Tissue Atlas Coexpression human GTEx RNA, mouse GNFv3 RNA, mouse protein
CCLE cell lines CRISPR-codependency, RNA-seq coexpression, RNA-microarray, CRISPR-vs-RNA-seq
Sequence Alignment (MitoCarta only) all_BBH, selected_BBH

MitoCarta3.0
In MitoCarta3.0?0
Evidence0
MitoPathway
Sub-Mito Localization
MS/MS tissues
MitoCarta2.0 FDR0.887
MitoCarta2.0 TrainingTnon_mito
TargetP_v1 MTS Confidence
MitoDomainNonMitoDomain
Yeast HomologNoMitoHomolog
Rickettsia HomologNoHomolog
GeneAtlas Coexpression N50 NA
PGC Induction
MSMS score
MSMS intensitycerebrum:, cerebellum:, brainstem:, spinalcord:, kidney:, liver:, heart:, muscle:, adipose:, sm_intestine:, lg_intestine:, stomach:, placenta:, testis:
MSMS unique peps
Curator notes

Miscellaneous features
HPA Main Location (2020)
PFAM domains (2022)7tm_1
CRISPR guides

Mootha Lab CRISPR Screen Results
Glu/Gal Death Screen (2016)not strongly enriched in Gal/Glu dead cells (fdr=1)
O2 Screen Summary (2020)not selectively essential in 1% vs 21% oxygen (fdr=1)
1%O2_vs_21%O2.day15.score (2020)0
21%O2.day15_vs_day0.score (2020)0
Chemical Genetics Zscore (To 2019)
TMRM Oligo Zscore (unpublished)

Refseq Protein Isoforms
Species mRNA ProteinID Len (AA) TargetP v1.0 TargetP v2.0 TPpred2 MitoFates Mouse Best TMHMM # Helices TMHMM Topology
humanNM_005303NP_005294 300S (conf=2)noTPnoMTS (score=1)7o5-27i40-59o79-101i122-144o188-210i223-245o260-282i
mouseNM_194057NP_918946 300S (conf=2)noTPnoMTS (score=1)7o10-32i39-61o81-103i122-144o188-210i223-245o260-282i