FAR1: fatty acyl-CoA reductase 1

All genes, All MitoCarta3.0 genes, FAQ

Human synonymsFAR1 | MLSTD2|PFCRD|SDR10E1 | GeneID:84188 | ENSG00000197601 | Q8WVX9
Mouse orthologFar1 | 2600011M19Rik|2900034E22Rik|3732409C05Rik|AI850429|Mlst|Mlstd2 | GeneID:67420 | ENSMUSG00000030759 | Q922J9

MoothaLab Resources
Tissue Atlas Coexpression human GTEx RNA, mouse GNFv3 RNA, mouse protein
CCLE cell lines CRISPR-codependency, RNA-seq coexpression, RNA-microarray, CRISPR-vs-RNA-seq
Sequence Alignment (MitoCarta only) all_BBH, selected_BBH

MitoCarta3.0
In MitoCarta3.0?0
Evidencemito protein domain
MitoPathway
Sub-Mito Localization
MS/MS tissues
MitoCarta2.0 FDR0.767
MitoCarta2.0 TrainingTnon_mito
TargetP_v1 MTS Confidence
MitoDomainSharedDomain
Yeast HomologNoMitoHomolog
Rickettsia HomologNoHomolog
GeneAtlas Coexpression N50 1
PGC Induction
MSMS score
MSMS intensitycerebrum:, cerebellum:, brainstem:, spinalcord:, kidney:, liver:, heart:, muscle:, adipose:, sm_intestine:, lg_intestine:, stomach:, placenta:, testis:
MSMS unique peps
Curator notes

Miscellaneous features
HPA Main Location (2020)Peroxisomes (Supported)
PFAM domains (2022)NAD_binding_4|Sterile
CRISPR guides

Mootha Lab CRISPR Screen Results
Glu/Gal Death Screen (2016)not strongly enriched in Gal/Glu dead cells (fdr=1)
O2 Screen Summary (2020)Selectively essential in 21% vs 1% oxygen (fdr=0.0002)
1%O2_vs_21%O2.day15.score (2020)-3.7
21%O2.day15_vs_day0.score (2020)0.3
Chemical Genetics Zscore (To 2019)
TMRM Oligo Zscore (unpublished)-1.6

Refseq Protein Isoforms
Species mRNA ProteinID Len (AA) TargetP v1.0 TargetP v2.0 TPpred2 MitoFates Mouse Best TMHMM # Helices TMHMM Topology
mouseNM_001285831NP_001272760 515no pred (conf=2)noTPnoMTS (score=1)1o466-483i
mouseNM_027379NP_081655 515no pred (conf=2)noTPnoMTS (score=1)1o466-483i
humanNM_032228NP_115604 515no pred (conf=2)noTPnoMTS (score=1)1o466-483i