COIL: Complexity Of Infection Likelihood calculator
Complex malaria infections are defined as those containing more than one genetically distinct lineage of Plasmodium parasite. Complexity of infection (COI) is a useful parameter to estimate from patient blood samples because it is associated with clinical outcome, epidemiology, and disease transmission rate. COIL is a method for estimating COI using likehood from a panel of genotyping assays for bi-alellic SNPs. Please see the User Guide for a complete set of instructions.
To run COIL, select an input file using the Browse button below, then click Submit.
Data from submitted input files are not kept on Broad servers.
Citation
Galinsky K, Valim C, Salmier A, de Thoisy B, Musset L, Legrand E, Faust A, Baniecki ML, Ndiaye D, Daniels RF, Hartl DL, Sabeti PC, Wirth DF, Volkman SK, Neafsey DE. COIL: a methodology for evaluating malarial complexity of infection using likelihood from single nucleotide polymorphism data. Malar J. 2015 Jan 19;14(1):4. PubMed PMID: 25599890; PubMed Central PMCID: PMC4417311.