WSCD1: WSC domain containing 1

All genes, All MitoCarta3.0 genes, FAQ

Human synonymsWSCD1 | - | GeneID:23302 | ENSG00000179314 | Q658N2
Mouse orthologWscd1 | mKIAA0523 | GeneID:216881 | ENSMUSG00000020811 | Q80XH4

MoothaLab Resources
Tissue Atlas Coexpression human GTEx RNA, mouse GNFv3 RNA, mouse protein
CCLE cell lines CRISPR-codependency, RNA-seq coexpression, RNA-microarray, CRISPR-vs-RNA-seq
Sequence Alignment (MitoCarta only) all_BBH, selected_BBH

MitoCarta3.0
In MitoCarta3.0?0
Evidence0
MitoPathway
Sub-Mito Localization
MS/MS tissues
MitoCarta2.0 FDR0.887
MitoCarta2.0 TrainingTnon_mito
TargetP_v1 MTS Confidence
MitoDomainNonMitoDomain
Yeast HomologNoMitoHomolog
Rickettsia HomologNoHomolog
GeneAtlas Coexpression N50 0
PGC Induction
MSMS score
MSMS intensitycerebrum:, cerebellum:, brainstem:, spinalcord:, kidney:, liver:, heart:, muscle:, adipose:, sm_intestine:, lg_intestine:, stomach:, placenta:, testis:
MSMS unique peps
Curator notes

Miscellaneous features
HPA Main Location (2020)Nucleoplasm (Approved)
PFAM domains (2022)Sulfotransfer_1|WSC
CRISPR guides

Mootha Lab CRISPR Screen Results
Glu/Gal Death Screen (2016)not strongly enriched in Gal/Glu dead cells (fdr=1)
O2 Screen Summary (2020)not selectively essential in 1% vs 21% oxygen (fdr=1)
1%O2_vs_21%O2.day15.score (2020)0
21%O2.day15_vs_day0.score (2020)0
Chemical Genetics Zscore (To 2019)
TMRM Oligo Zscore (unpublished)

Refseq Protein Isoforms
Species mRNA ProteinID Len (AA) TargetP v1.0 TargetP v2.0 TPpred2 MitoFates Mouse Best TMHMM # Helices TMHMM Topology
humanNM_015253NP_056068 575S (conf=4)noTPnoMTS (score=0.71)1i17-36o
mouseNM_177618NP_808286 572S (conf=4)noTPnoMTS (score=0.96)1i17-36o