PEDS1-UBE2V1: PEDS1-UBE2V1 readthrough

All genes, All MitoCarta3.0 genes, FAQ

Human synonymsPEDS1-UBE2V1 | CROC-1B|CROC1B|KUA-UEV|TMEM189-UBE2V1 | GeneID:387522 | ENSG00000124208 | 0
Mouse ortholog | | GeneID: | |

MoothaLab Resources
Tissue Atlas Coexpression human GTEx RNA, mouse GNFv3 RNA, mouse protein
CCLE cell lines CRISPR-codependency, RNA-seq coexpression, RNA-microarray, CRISPR-vs-RNA-seq
Sequence Alignment (MitoCarta only) all_BBH, selected_BBH

MitoCarta3.0
In MitoCarta3.0?0
Evidence0
MitoPathway
Sub-Mito Localization
MS/MS tissues
MitoCarta2.0 FDR0.924
MitoCarta2.0 TrainingTnon_mito
TargetP_v1 MTS Confidence
MitoDomainNonMitoDomain
Yeast HomologNoMitoHomolog
Rickettsia HomologNoHomolog
GeneAtlas Coexpression N50 
PGC Induction
MSMS score
MSMS intensitycerebrum:, cerebellum:, brainstem:, spinalcord:, kidney:, liver:, heart:, muscle:, adipose:, sm_intestine:, lg_intestine:, stomach:, placenta:, testis:
MSMS unique peps
Curator notes

Miscellaneous features
HPA Main Location (2020)Nucleoplasm (Supported)
PFAM domains (2022)Lipid_desat|UQ_con
CRISPR guides

Mootha Lab CRISPR Screen Results
Glu/Gal Death Screen (2016)not strongly enriched in Gal/Glu dead cells (fdr=1)
O2 Screen Summary (2020)Selectively essential in 21% vs 1% oxygen (fdr=0.0002)
1%O2_vs_21%O2.day15.score (2020)-3.7
21%O2.day15_vs_day0.score (2020)0.1
Chemical Genetics Zscore (To 2019)
TMRM Oligo Zscore (unpublished)

Refseq Protein Isoforms
Species mRNA ProteinID Len (AA) TargetP v1.0 TargetP v2.0 TPpred2 MitoFates Mouse Best TMHMM # Helices TMHMM Topology
humanNM_199203NP_954673 370no pred (conf=2)noTPnoMTS (score=1)2o46-68i75-97o