PDCD10: programmed cell death 10

All genes, All MitoCarta3.0 genes, FAQ

Human synonymsPDCD10 | CCM3|TFAR15 | GeneID:11235 | ENSG00000114209 | Q9BUL8
Mouse orthologPdcd10 | 2410003B13Rik|Ccm3|Tfa1|Tfa15|Tfar15 | GeneID:56426 | ENSMUSG00000027835 | Q8VE70

MoothaLab Resources
Tissue Atlas Coexpression human GTEx RNA, mouse GNFv3 RNA, mouse protein
CCLE cell lines CRISPR-codependency, RNA-seq coexpression, RNA-microarray, CRISPR-vs-RNA-seq
Sequence Alignment (MitoCarta only) all_BBH, selected_BBH

MitoCarta3.0
In MitoCarta3.0?0
Evidence0
MitoPathway
Sub-Mito Localization
MS/MS tissuesbrainstem
MitoCarta2.0 FDR0.869
MitoCarta2.0 TrainingTnon_mito
TargetP_v1 MTS Confidence
MitoDomainNonMitoDomain
Yeast HomologNoMitoHomolog
Rickettsia HomologNoHomolog
GeneAtlas Coexpression N50 0
PGC Induction
MSMS score0-25ambig
MSMS intensitycerebrum:, cerebellum:, brainstem:7.6, spinalcord:, kidney:, liver:, heart:, muscle:, adipose:, sm_intestine:, lg_intestine:, stomach:, placenta:, testis:
MSMS unique peps2
Curator notes

Miscellaneous features
HPA Main Location (2020)
PFAM domains (2022)DUF1241
CRISPR guides

Mootha Lab CRISPR Screen Results
Glu/Gal Death Screen (2016)not strongly enriched in Gal/Glu dead cells (fdr=1)
O2 Screen Summary (2020)not selectively essential in 1% vs 21% oxygen (fdr=1)
1%O2_vs_21%O2.day15.score (2020)0
21%O2.day15_vs_day0.score (2020)0
Chemical Genetics Zscore (To 2019)
TMRM Oligo Zscore (unpublished)-1.8

Refseq Protein Isoforms
Species mRNA ProteinID Len (AA) TargetP v1.0 TargetP v2.0 TPpred2 MitoFates Mouse Best TMHMM # Helices TMHMM Topology
humanNM_145860NP_665859 212no pred (conf=2)noTPnoMTS (score=1)0o
humanNM_145859NP_665858 212no pred (conf=2)noTPnoMTS (score=1)0o
humanNM_007217NP_009148 212no pred (conf=2)noTPnoMTS (score=1)0o
mouseNM_019745NP_062719 212no pred (conf=2)noTPnoMTS (score=1)0o