FFAR4: free fatty acid receptor 4

All genes, All MitoCarta3.0 genes, FAQ

Human synonymsFFAR4 | BMIQ10|GPR120|GPR129|GT01|O3FAR1|PGR4 | GeneID:338557 | ENSG00000186188 | Q5NUL3
Mouse orthologFfar4 | AI552415|Ffa|Ffa4|GT01|Gpr1|Gpr120|Gpr129|KPG_013|O3f|O3far1|Pg|Pgr4 | GeneID:107221 | ENSMUSG00000054200 | Q7TMA4

MoothaLab Resources
Tissue Atlas Coexpression human GTEx RNA, mouse GNFv3 RNA, mouse protein
CCLE cell lines CRISPR-codependency, RNA-seq coexpression, RNA-microarray, CRISPR-vs-RNA-seq
Sequence Alignment (MitoCarta only) all_BBH, selected_BBH

MitoCarta3.0
In MitoCarta3.0?0
Evidence0
MitoPathway
Sub-Mito Localization
MS/MS tissues
MitoCarta2.0 FDR0.866
MitoCarta2.0 TrainingTnon_mito
TargetP_v1 MTS Confidence4
MitoDomainNonMitoDomain
Yeast HomologNoMitoHomolog
Rickettsia HomologNoHomolog
GeneAtlas Coexpression N50 0
PGC Induction
MSMS score
MSMS intensitycerebrum:, cerebellum:, brainstem:, spinalcord:, kidney:, liver:, heart:, muscle:, adipose:, sm_intestine:, lg_intestine:, stomach:, placenta:, testis:
MSMS unique peps
Curator notes

Miscellaneous features
HPA Main Location (2020)Plasma membrane (Uncertain)
PFAM domains (2022)7tm_1
CRISPR guides

Mootha Lab CRISPR Screen Results
Glu/Gal Death Screen (2016)not strongly enriched in Gal/Glu dead cells (fdr=1)
O2 Screen Summary (2020)not selectively essential in 1% vs 21% oxygen (fdr=0.9155)
1%O2_vs_21%O2.day15.score (2020)0.1
21%O2.day15_vs_day0.score (2020)0
Chemical Genetics Zscore (To 2019)
TMRM Oligo Zscore (unpublished)

Refseq Protein Isoforms
Species mRNA ProteinID Len (AA) TargetP v1.0 TargetP v2.0 TPpred2 MitoFates Mouse Best TMHMM # Helices TMHMM Topology
humanNM_181745NP_859529 377MTS (conf=4)noTPnoMTS (score=1)7o44-66i75-97o112-134i155-177o209-231i283-305o315-337i
humanNM_001195755NP_001182684 361MTS (conf=4)noTPnoMTS (score=1)7o44-66i75-97o112-134i155-177o209-231i267-289o299-321i
mouseNM_181748NP_861413 361no pred (conf=4)noTPnoMTS (score=1)7o44-66i75-97o112-134i158-180o209-231i267-289o304-326i