CYTH1: cytohesin 1

All genes, All MitoCarta3.0 genes, FAQ

Human synonymsCYTH1 | B2-1|CYTOHESIN-1|D17S811E|PSCD1|SEC7 | GeneID:9267 | ENSG00000108669 | Q15438
Mouse orthologCyth1 | CLM|CLM1|CTH-1|CYTIP|Psc|Pscd1 | GeneID:19157 | ENSMUSG00000017132 | Q9QX11

MoothaLab Resources
Tissue Atlas Coexpression human GTEx RNA, mouse GNFv3 RNA, mouse protein
CCLE cell lines CRISPR-codependency, RNA-seq coexpression, RNA-microarray, CRISPR-vs-RNA-seq
Sequence Alignment (MitoCarta only) all_BBH, selected_BBH

MitoCarta3.0
In MitoCarta3.0?0
EvidenceRickettsial homolog, mito protein domain, induction
MitoPathway
Sub-Mito Localization
MS/MS tissues
MitoCarta2.0 FDR0.203
MitoCarta2.0 TrainingTnon_mito
TargetP_v1 MTS Confidence
MitoDomainSharedDomain
Yeast HomologNoMitoHomolog
Rickettsia HomologHomolog
GeneAtlas Coexpression N50 1
PGC Induction1.96
MSMS score
MSMS intensitycerebrum:, cerebellum:, brainstem:, spinalcord:, kidney:, liver:, heart:, muscle:, adipose:, sm_intestine:, lg_intestine:, stomach:, placenta:, testis:
MSMS unique peps
Curator notes

Miscellaneous features
HPA Main Location (2020)Nucleoplasm (Uncertain)
PFAM domains (2022)PH|Sec7
CRISPR guides

Mootha Lab CRISPR Screen Results
Glu/Gal Death Screen (2016)not strongly enriched in Gal/Glu dead cells (fdr=0.87)
O2 Screen Summary (2020)not selectively essential in 1% vs 21% oxygen (fdr=1)
1%O2_vs_21%O2.day15.score (2020)0
21%O2.day15_vs_day0.score (2020)-0.1
Chemical Genetics Zscore (To 2019)
TMRM Oligo Zscore (unpublished)0.6

Refseq Protein Isoforms
Species mRNA ProteinID Len (AA) TargetP v1.0 TargetP v2.0 TPpred2 MitoFates Mouse Best TMHMM # Helices TMHMM Topology
mouseNM_001112700NP_001106170 400no pred (conf=1)noTPnoMTS (score=1)0o
humanNM_004762NP_004753 398no pred (conf=1)noTPnoMTS (score=1)0o
mouseNM_001112699NP_001106169 397no pred (conf=1)noTPnoMTS (score=1)0o
mouseNM_011180NP_035310 398no pred (conf=1)noTPnoMTS (score=1)0o
humanNM_017456NP_059430 397no pred (conf=1)noTPnoMTS (score=1)0o