Since joining the Broad in 2009, I have engaged in dozens of projects centered on functional genomics with a wide variety of research groups across many areas of biology. In these collaborations, my role is to provide expert guidance on the design, execution, and analysis of genetic screens. Additionally, I have many years of experience in the development and use of functional genomic techniques, first with RNAi and more recently with CRISPR technology. As leader of R&D in the Platform, I have stayed on the cutting-edge of newest techniques while also focusing on the reduction-to-practice that is critical for enabling collaboration with a broader community of researchers. Prior to the Broad, I performed postdoctoral research with Ed Harlow at Harvard Medical School, trained at MIT with Phil Sharp for my Ph.D. in biology, and majored in history at Hamilton College.
I graduated with a degree in Computer Science and Engineering in 2011 from a university in Bangalore, India. In the same year, I moved to Boston to pursue my Masters in Bioinformatics at Northeastern University. I started interning at the Broad in 2012 mainly analyzing RNAi screening data. Now, as a full-time computational biologist in the GPP, I am involved in analyzing and developing tools to analyze functional genomic screens. I also have experience in designing perturbations for functional genomics screens. In addition to spending time at the Broad, I learn Indian classical dance and love to read.
Christine is a transplant from the Midwest. She grew up in the in Minnesota and attended Uni. of Wisc.- Madison. She graduated in 2015 with a B.Sc. in Biochemistry. Prior to the Broad, she worked in clinical research and in vitro diagnostics. She plans on continuing her studies and intends to spend her career working in translational research. Her free time is spent reading, sketching, and exploring the city.
Originally from the West Coast, I was born and raised on Bainbridge Island, Washington in the great Pacific Northwest. I most recently moved from Los Angeles, California where I received a B.S. in Global Health in 2015 and a M.S. in Stem Cell Biology and Regenerative Medicine in 2016 from the University of Southern California. My research background is in the production and packaging of gene editing tools into AAV as a means to disrupt the function of the CCR5 HIV co-receptor. When I'm not in the lab I am most likely sailing the high seas, skiing, watching football or drinking coffee.
I grew up in Newton, MA and moved to Providence, RI to complete my undergraduate degree at Brown University in Health and Human Biology. Having lived in New England for most of my life, I'm happy to be back in Boston working at the Broad. My background is in cancer biology, and at Brown I completed a senior thesis examining the sigma-2 receptor apoptotic pathway in neuroblastoma. Aside from spending late nights in lab, I can also be found exploring food and coffee places, traveling, and biking.
Originally from the Boston area, I briefly left Massachusetts for New Haven, where I received a B.S. in Molecular, Cellular, and Developmental Biology and Women's, Gender, and Sexuality Studies from Yale University in 2017. At Yale, I studied chemoresistance in BRCA2-mutant ovarian cancer and researched the history of environmental cancer activism. I began working at the Broad in July 2017. When not in lab, I can most likely be found chasing discs on the ultimate frisbee field or seeking out the finest ice cream in Boston.
Alexandra East (Seletsky), Graduate Student, University of California, Berkeley
Peyton Greenside, Graduate Student, Stanford University
Ella Hartenian, Graduate Student, University of California, Berkeley