Shown are top 300 and bottom 300 genes based on Pearson correlation between this gene and 17672 other genes using cancer dependency profiles (dependency across 391 cancer cell lines). Bold indicates MitoCarta2.0 gene. Note that if this gene is always expressed (CDM meanD>0.9) or rarely expressed (CDM meanD<0.1) then these correlations are unlikely to be useful, as they are probably driven by one or two outlier cell lines. CDM dependency is a score between 0 (no growth defect in cell line) and 1 (extreme growth defect in cell line). TPM is a log2 representation of RNA-seq expression.

Rank Corr Symbol Description MitoCarta2.0 CDM meanD CDM range TPM mean TPM range Entrez UniProt

1 1 AKR7A2 "aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase)" 1 0.05 0-0.35 5.1 3-7.4 8574 O43488

2 0.370 FGFBP1 fibroblast growth factor binding protein 1 0 0.02 0-0.38 0.5 -3-11.2 9982 Q14512

3 0.370 C2orf72 chromosome 2 open reading frame 72 0 0 0-0.1 -0.5 -3-6.4 257407 A6NCS6

4 0.362 PCBD2 pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 2 1 0.08 0-0.85 3 0-5.2 84105 Q9H0N5

5 0.360 ATP10B "ATPase, class V, type 10B" 0 0.03 0-0.72 -2 -3-6.3 23120 O94823

6 0.356 VSIG2 V-set and immunoglobulin domain containing 2 0 0 0-0.15 -2.2 -3-7.6 23584 Q96IQ7

7 0.343 TPRG1L tumor protein p63 regulated 1-like 0 0.09 0-0.61 4 -3-6.6 127262 Q5T0D9

8 0.339 TUBAL3 "tubulin, alpha-like 3" 0 0.01 0-0.29 -2.3 -3-4.7 79861 A6NHL2

9 0.334 CNIH3 cornichon family AMPA receptor auxiliary protein 3 0 0.02 0-0.39 1.3 -3-7.1 149111 Q8TBE1

10 0.332 SFRP4 secreted frizzled-related protein 4 0 0.03 0-0.47 -2.1 -3-9.9 6424 Q6FHJ7

11 0.327 TXNDC5 thioredoxin domain containing 5 (endoplasmic reticulum) 0 0.01 0-0.29 7.2 4.6-12.5 81567 Q8NBS9

12 0.326 CD28 CD28 molecule 0 0 0-0.12 -2.5 -3-8.1 940 P10747

13 0.325 EPHX2 "epoxide hydrolase 2, cytoplasmic" 1 0.01 0-0.23 1.3 -3-8.1 2053 P34913

14 0.324 CYTL1 cytokine-like 1 0 0.01 0-0.19 -1.5 -3-9.9 54360 Q9NRR1

15 0.323 FAM174B "family with sequence similarity 174, member B" 0 0.02 0-0.34 1.7 -3-7.6 400451 Q3ZCQ3

16 0.322 GPM6A glycoprotein M6A 0 0.01 0-0.43 -1.7 -3-7.7 2823 P51674

17 0.319 PKD2L2 polycystic kidney disease 2-like 2 0 0.01 0-0.15 -2.7 -3-0.3 27039 Q9NZM6

18 0.319 FN1 fibronectin 1 0 0.02 0-0.32 6.1 -0.6-15.3 2335 P02751

19 0.319 FAM163B "family with sequence similarity 163, member B" 0 0 0-0.08 -2.5 -3-6 642968 P0C2L3

20 0.318 SH3BGRL2 SH3 domain binding glutamic acid-rich protein like 2 0 0.01 0-0.2 1.2 -3-6.7 83699 Q9UJC5

21 0.318 LGI3 "leucine-rich repeat LGI family, member 3" 0 0.01 0-0.32 -2.5 -3-7.5 203190 Q8N145

22 0.317 DLEU7 "deleted in lymphocytic leukemia, 7" 0 0.01 0-0.24 -2.1 -3-5.1 220107 Q6UYE1

23 0.315 METTL21A methyltransferase like 21A 0 0.01 0-0.24 4.4 1.8-6.7 151194 Q8WXB1

24 0.314 GNAL "guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type" 0 0 0-0.15 0 -3-6.5 2774 P38405

25 0.312 MSANTD1 Myb/SANT-like DNA-binding domain containing 1 0 0.01 0-0.28 -2.4 -3-1.1 345222 Q6ZTZ1

26 0.311 LRRFIP1 leucine rich repeat (in FLII) interacting protein 1 0 0.02 0-0.41 5.8 -1-8 9208 Q32MZ4

27 0.310 MFSD2B major facilitator superfamily domain containing 2B 0 0.01 0-0.14 -2.6 -3-5.1 388931 A6NFX1

28 0.310 KNOP1 lysine-rich nucleolar protein 1 0 0.01 0-0.21 4.8 1.4-6.9 400506 Q1ED39

29 0.309 THADA thyroid adenoma associated 0 0.01 0-0.08 3.7 -3-5.9 63892 Q6YHU6

30 0.308 MYLK4 "myosin light chain kinase family, member 4" 0 0.01 0-0.62 -2 -3-3.8 340156 Q86YV6

31 0.307 RAET1E retinoic acid early transcript 1E 0 0 0-0.1 -1.2 -3-5.2 135250 Q8TD07

32 0.307 CRABP1 cellular retinoic acid binding protein 1 0 0.01 0-0.57 -1.3 -3-10.6 1381 P29762

33 0.306 NINL ninein-like 0 0.01 0-0.26 2.2 -3-8.1 22981 Q9Y2I6

34 0.305 HEXB hexosaminidase B (beta polypeptide) 0 0.02 0-0.45 6.6 -0.6-9.2 3074 P07686

35 0.305 AGMAT agmatine ureohydrolase (agmatinase) 1 0.08 0-0.49 -0.2 -3-6.7 79814 Q9BSE5

36 0.304 ZNF773 zinc finger protein 773 0 0.01 0-0.21 2.2 -3-4.9 374928 Q6PK81

37 0.304 SCXB scleraxis homolog B (mouse) 0 0 0-0.04 642658 Q7RTU7

38 0.303 UPK3B uroplakin 3B 0 0.01 0-0.38 0 -3-10.1 80761 Q9BT76

39 0.303 SLC45A4 "solute carrier family 45, member 4" 0 0.02 0-0.43 2.4 -3-6.5 57210 Q5BKX6

40 0.303 SHISA4 shisa family member 4 0 0.02 0-0.5 2.7 -3-7.4 149345 Q96DD7

41 0.303 CHAC1 "ChaC, cation transport regulator homolog 1 (E. coli)" 0 0.03 0-0.52 3 -3-7.3 79094 Q9BUX1

42 0.302 SOCS4 suppressor of cytokine signaling 4 0 0.05 0-0.4 3.4 0.7-5.8 122809 Q8WXH5

43 0.302 LY6D "lymphocyte antigen 6 complex, locus D" 0 0.02 0-0.3 -1.4 -3-11.2 8581 Q14210

44 0.302 DBNL drebrin-like 0 0.03 0-0.52 6.3 3.7-8.2 28988 Q9UJU6

45 0.300 PALLD "palladin, cytoskeletal associated protein" 0 0.01 0-0.47 4 -3-9.1 23022 Q8WX93

46 0.300 HMGB2 high mobility group box 2 0 0 0-0.1 8.3 1-11.2 3148 P26583

47 0.300 ATP13A2 ATPase type 13A2 0 0.08 0-0.84 4.5 -0.5-8.1 23400 Q9NQ11

48 0.298 UBXN10 UBX domain protein 10 0 0.03 0-0.43 -2.1 -3-4.9 127733 Q96LJ8

49 0.298 PECR peroxisomal trans-2-enoyl-CoA reductase 0 0.04 0-0.7 3 -3-6.7 55825 Q9BY49

50 0.298 PCYOX1L prenylcysteine oxidase 1 like 0 0.01 0-0.19 3 -3-5.8 78991 Q8NBM8

51 0.298 FAM65A "family with sequence similarity 65, member A" 0 0.02 0-0.77 4.6 -1.2-7.7 79567 Q6ZS17

52 0.298 CLTCL1 "clathrin, heavy chain-like 1" 0 0.05 0-0.44 1.7 -3-6 8218 P53675

53 0.298 AOX1 aldehyde oxidase 1 0 0.01 0-0.23 -0.1 -3-8.1 316 Q06278

54 0.297 ABCA7 "ATP-binding cassette, sub-family A (ABC1), member 7" 0 0.02 0-0.38 3.4 -2.3-7.8 10347 Q8IZY2

55 0.296 KRTAP25-1 keratin associated protein 25-1 0 0 0-0.15 -3 -3--2.8 100131902 Q3LHN0

56 0.296 HGSNAT heparan-alpha-glucosaminide N-acetyltransferase 0 0.01 0-0.25 4 0.3-7.8 138050 Q68CP4

57 0.296 ANGPT4 angiopoietin 4 0 0 0-0.18 -2.9 -3-3 51378 Q9Y264

58 0.295 DFFA "DNA fragmentation factor, 45kDa, alpha polypeptide" 0 0.04 0-0.36 4.8 1.8-6.5 1676 O00273

59 0.295 CCDC11 coiled-coil domain containing 11 0 0 0-0.24 -1.4 -3-3.5 220136 Q96M91

60 0.294 TCF15 transcription factor 15 (basic helix-loop-helix) 0 0 0-0.21 -2.3 -3-3.2 6939 Q12870

61 0.293 HAGHL hydroxyacylglutathione hydrolase-like 0 0.03 0-0.5 3.7 -0.8-7.3 84264 Q6PII5

62 0.293 DGAT2 diacylglycerol O-acyltransferase 2 0 0.01 0-0.28 2.1 -3-7.4 84649 Q96PD7

63 0.292 CNTF ciliary neurotrophic factor 0 0.04 0-0.45 0.1 -3-3.3 1270 P26441

64 0.291 PTPLA "protein tyrosine phosphatase-like (proline instead of catalytic arginine), member A" 0 0.02 0-0.24 3.1 -3-8.1 9200 B0YJ81

65 0.290 PCDHAC2 "protocadherin alpha subfamily C, 2" 0 0.04 0-0.36 -1.6 -3-4.1 56134 Q9Y5I4

66 0.290 CXXC5 CXXC finger protein 5 0 0.01 0-0.23 4.4 -2.7-8.3 51523 Q7LFL8

67 0.290 ALOX5AP arachidonate 5-lipoxygenase-activating protein 0 0.01 0-0.53 -0.4 -3-10.2 241 P20292

68 0.289 FAM24B "family with sequence similarity 24, member B" 0 0.03 0-0.6 2.6 -3-5.8 196792 Q8N5W8

69 0.289 CCDC28A coiled-coil domain containing 28A 0 0.01 0-0.11 3.6 0.9-6 25901 Q8IWP9

70 0.288 GPR88 G protein-coupled receptor 88 0 0.03 0-0.45 -2.9 -3-2.8 54112 Q9GZN0

71 0.288 DIO3 "deiodinase, iodothyronine, type III" 0 0.01 0-0.65 -2.4 -3-8.1 1735 P55073

72 0.288 CACHD1 cache domain containing 1 0 0.03 0-0.36 0.7 -3-6.8 57685 Q5VU97

73 0.287 TMEM173 transmembrane protein 173 0 0.01 0-0.1 3.6 -3-9.2 340061 Q86WV6

74 0.287 GCA "grancalcin, EF-hand calcium binding protein" 0 0.01 0-0.14 3.4 -3-8.2 25801 P28676

75 0.286 RALBP1 ralA binding protein 1 0 0.03 0-0.54 5 2.2-8.1 10928 Q15311

76 0.286 PDE3B "phosphodiesterase 3B, cGMP-inhibited" 0 0.01 0-0.17 0.1 -3-6 5140 Q13370

77 0.286 OR52N2 "olfactory receptor, family 52, subfamily N, member 2" 0 0.01 0-0.54 -3 -3-0.3 390077 Q8NGI0

78 0.285 HECA headcase homolog (Drosophila) 0 0.01 0-0.31 2.2 -3-5.7 51696 Q9UBI9

79 0.284 ROS1 "c-ros oncogene 1 , receptor tyrosine kinase" 0 0.01 0-0.22 -2.3 -3-6.2 6098 P08922

80 0.283 TMEM236 transmembrane protein 236 0 0 0-0.02 -2.9 -3-4 653567 Q5W0B7

81 0.283 CPLX1 complexin 1 0 0.01 0-0.5 0.1 -3-7 10815 O14810

82 0.282 ELK4 "ELK4, ETS-domain protein (SRF accessory protein 1)" 0 0 0-0.3 3.1 0.9-5.8 2005 P28324

83 0.281 PRDX5 peroxiredoxin 5 1 0.14 0-0.84 8.3 6-10.1 25824 P30044

84 0.281 DXO decapping exoribonuclease 0 0.07 0-0.44 4.2 2-6.3 1797 O77932

85 0.280 TMUB1 transmembrane and ubiquitin-like domain containing 1 0 0.01 0-0.22 5.4 3.3-7.3 83590 Q9BVT8

86 0.280 NELL1 NEL-like 1 (chicken) 0 0 0-0.02 -2.3 -3-7.5 4745 Q92832

87 0.279 ZNF611 zinc finger protein 611 0 0 0-0.02 2.2 -3-5.3 81856 Q8N823

88 0.279 TNFRSF10B "tumor necrosis factor receptor superfamily, member 10b" 0 0 0-0.04 5.3 -3-9.3 8795 O14763

89 0.279 NPPB natriuretic peptide B 0 0.02 0-0.43 -1.8 -3-10.4 4879 P16860

90 0.279 NPFF neuropeptide FF-amide peptide precursor 0 0.05 0-0.45 -0.1 -3-4.8 8620 O15130

91 0.278 TNK2 "tyrosine kinase, non-receptor, 2" 0 0.01 0-0.37 4.6 0-7.9 10188 Q07912

92 0.278 TMEM170A transmembrane protein 170A 0 0.02 0-0.77 3.7 1.5-5.8 124491 Q8WVE7

93 0.278 MURC muscle-related coiled-coil protein 0 0.01 0-0.2 -0.8 -3-4.7 347273 Q5BKX8

94 0.276 TTC32 tetratricopeptide repeat domain 32 0 0.01 0-0.24 3.5 -3-7.6 130502 Q5I0X7

95 0.276 TRADD TNFRSF1A-associated via death domain 0 0.03 0-0.69 3.6 -3-5.7 8717 Q15628

96 0.276 MRAS muscle RAS oncogene homolog 0 0.04 0-0.65 1.8 -3-8.3 22808 O14807

97 0.276 GIMAP2 "GTPase, IMAP family member 2" 0 0 0-0.07 0 -3-7.4 26157 Q9UG22

98 0.276 FHDC1 FH2 domain containing 1 0 0.01 0-0.1 0.1 -3-5.7 85462 Q9C0D6

99 0.276 BRI3BP BRI3 binding protein 0 0.04 0-0.62 3.8 -0.1-8.8 140707 Q8WY22

100 0.275 ZFYVE16 "zinc finger, FYVE domain containing 16" 0 0.04 0-0.39 3.4 -0.5-7.1 9765 Q7Z3T8

101 0.275 TATDN2 TatD DNase domain containing 2 0 0.04 0-0.54 4.3 -3-7.6 9797 Q93075

102 0.274 TAS1R3 "taste receptor, type 1, member 3" 0 0.03 0-0.22 -1.6 -3-6.4 83756 Q7RTX0

103 0.274 MYCT1 myc target 1 0 0.02 0-0.46 -2.5 -3-5.6 80177 Q8N699

104 0.273 XDH xanthine dehydrogenase 0 0.01 0-0.22 -1 -3-5.9 7498 P47989

105 0.273 TANC1 "tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1" 0 0.02 0-0.19 3.1 -3-6.5 85461 Q9C0D5

106 0.273 NIPAL1 NIPA-like domain containing 1 0 0 0-0.09 1.1 -3-5.3 152519 Q6NVV3

107 0.273 MOCOS molybdenum cofactor sulfurase 0 0.01 0-0.32 0.8 -3-6.1 55034 Q96EN8

108 0.273 C21orf140 chromosome 21 open reading frame 140 0 0 0-0.12 -1.1 -3-2.6 101928147 B9A014

109 0.271 ZBTB49 zinc finger and BTB domain containing 49 0 0.02 0-0.27 1.4 -2.4-3.7 166793 Q6ZSB9

110 0.271 RBMS2 "RNA binding motif, single stranded interacting protein 2" 0 0 0-0.1 3 -3-6.6 5939 Q15434

111 0.271 PYGO1 pygopus family PHD finger 1 0 0.01 0-0.18 -0.2 -3-5.1 26108 Q9Y3Y4

112 0.271 PER1 period circadian clock 1 0 0 0-0.1 3.1 -0.9-6.9 5187 O15534

113 0.271 KLHL24 kelch-like family member 24 0 0.02 0-0.13 3.1 -0.6-6.7 54800 Q6TFL4

114 0.270 KCNA5 "potassium voltage-gated channel, shaker-related subfamily, member 5" 0 0.01 0-0.2 -2.9 -3-6.4 3741 P22460

115 0.270 APP amyloid beta (A4) precursor protein 0 0.03 0-0.41 7.8 -0.9-11.1 351 P05067

116 0.269 SLC9A2 "solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2" 0 0.02 0-0.31 -1.1 -3-6.3 6549 Q9UBY0

117 0.269 DNAH3 "dynein, axonemal, heavy chain 3" 0 0.02 0-0.4 -1.8 -3-4 55567 Q8TD57

118 0.269 CALML6 calmodulin-like 6 0 0.1 0-0.61 -1.6 -3-5.2 163688 Q8TD86

119 0.268 STK16 serine/threonine kinase 16 0 0.03 0-0.3 4.9 3.1-6.3 8576 O75716

120 0.268 PACRGL PARK2 co-regulated-like 0 0 0-0.1 3.9 1.8-6.3 133015 Q8N7B6

121 0.268 P2RX2 "purinergic receptor P2X, ligand-gated ion channel, 2" 0 0.14 0-0.64 -2.6 -3-5.9 22953 Q9UBL9

122 0.268 BBS7 Bardet-Biedl syndrome 7 0 0.01 0-0.34 3.6 -3-6.6 55212 Q8IWZ6

123 0.267 RILPL1 Rab interacting lysosomal protein-like 1 0 0.05 0-0.39 1.9 -3-4.6 353116 Q5EBL4

124 0.267 MRAP melanocortin 2 receptor accessory protein 0 0.02 0-0.18 -3 -3--1 56246 Q8TCY5

125 0.267 INO80D INO80 complex subunit D 0 0.02 0-0.51 1.4 -0.9-3.7 54891 Q53TQ3

126 0.267 DNALI1 "dynein, axonemal, light intermediate chain 1" 0 0.03 0-0.25 -0.8 -3-8.2 7802 O14645

127 0.267 AKR1D1 "aldo-keto reductase family 1, member D1" 0 0.03 0-0.45 -2.9 -3-4.1 6718 P51857

128 0.266 ANO7 anoctamin 7 0 0.02 0-0.18 0.1 -3-6.4 50636 Q6IWH7

129 0.266 ACY1 aminoacylase 1 0 0.03 0-0.34 4.7 0.1-7.5 95 Q03154

130 0.265 MCAM melanoma cell adhesion molecule 0 0.01 0-0.22 2.8 -3-10 4162 P43121

131 0.265 ARMC9 armadillo repeat containing 9 0 0.03 0-0.26 3.2 -3-8.5 80210 Q7Z3E5

132 0.264 TMTC4 transmembrane and tetratricopeptide repeat containing 4 0 0.01 0-0.22 3.6 -0.8-7.5 84899 Q5T4D3

133 0.264 GPATCH11 G patch domain containing 11 0 0.01 0-0.06 3 0.2-6 253635 Q8N954

134 0.264 CXCR6 chemokine (C-X-C motif) receptor 6 0 0.01 0-0.25 -2.2 -3-4.9 10663 O00574

135 0.264 CELA2B "chymotrypsin-like elastase family, member 2B" 0 0.02 0-0.49 -3 -3-1.3 51032 P08218

136 0.263 PCDHGC5 "protocadherin gamma subfamily C, 5" 0 0.03 0-0.35 -1.8 -3-6.6 56097 Q9Y5F6

137 0.263 HFE hemochromatosis 0 0.01 0-0.36 1.8 -3-6.1 3077 Q30201

138 0.263 CCNI2 "cyclin I family, member 2" 0 0.03 0-0.49 -1 -3-7.8 645121 Q6ZMN8

139 0.262 OR6Q1 "olfactory receptor, family 6, subfamily Q, member 1" 0 0.02 0-0.36 219952 Q8NGQ2

140 0.261 ZYG11A "zyg-11 family member A, cell cycle regulator" 0 0.02 0-0.18 -0.6 -3-3.9 440590 Q6WRX3

141 0.261 SEC14L5 SEC14-like 5 (S. cerevisiae) 0 0.03 0-0.37 -2.7 -3-4.3 9717 O43304

142 0.261 OR2V2 "olfactory receptor, family 2, subfamily V, member 2" 0 0.05 0-0.52 -3 -3-0.2 285659 Q96R30

143 0.261 FAM150B "family with sequence similarity 150, member B" 0 0 0-0.06 -2.3 -3-8.3 285016 Q6UX46

144 0.261 ATP5G3 "ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9)" 1 0.02 0-0.23 8.5 1.5-10.5 518 P48201

145 0.260 SRGAP1 SLIT-ROBO Rho GTPase activating protein 1 0 0.02 0-0.54 1.5 -3-5.5 57522 Q7Z6B7

146 0.260 SPATA31E1 "SPATA31 subfamily E, member 1" 0 0 0-0.08 -2.9 -3-3.7 286234 Q6ZUB1

147 0.260 ITM2C integral membrane protein 2C 0 0.07 0-0.45 6 -2.5-10.9 81618 Q9NQX7

148 0.260 GRIK3 "glutamate receptor, ionotropic, kainate 3" 0 0.03 0-0.44 -2.3 -3-8.1 2899 Q13003

149 0.260 FOPNL FGFR1OP N-terminal like 0 0.01 0-0.31 5.1 1.2-7 123811 Q96NB1

150 0.260 BAAT bile acid CoA: amino acid N-acyltransferase (glycine N-choloyltransferase) 0 0.01 0-0.44 -2.6 -3-5.2 570 Q14032

151 0.260 ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) 1 0.05 0-0.47 3.5 -3-9.1 217 P05091

152 0.259 TRAFD1 TRAF-type zinc finger domain containing 1 0 0.01 0-0.17 4.7 2.2-7.4 10906 O14545

153 0.259 RNF149 ring finger protein 149 0 0.04 0-0.43 4.6 -3-7 284996 Q8NC42

154 0.259 POLM "polymerase (DNA directed), mu" 0 0.07 0-0.74 3.6 0.9-6.6 27434 Q9NP87

155 0.259 C5orf46 chromosome 5 open reading frame 46 0 0 0-0.11 -1.8 -3-8.6 389336 Q6UWT4

156 0.259 C11orf31 chromosome 11 open reading frame 31 0 0.08 0-0.67 7.1 0.7-9 280636 Q8IZQ5

157 0.259 ADAMTS19 "ADAM metallopeptidase with thrombospondin type 1 motif, 19" 0 0 0-0.05 -2.6 -3-5.7 171019 Q8TE59

158 0.258 TTLL4 "tubulin tyrosine ligase-like family, member 4" 0 0.01 0-0.32 4.3 1.8-6.7 9654 Q14679

159 0.258 METAP1D methionyl aminopeptidase type 1D (mitochondrial) 1 0.02 0-0.25 2.7 -3-5.5 254042 Q6UB28

160 0.258 CCDC109B coiled-coil domain containing 109B 1 0 0-0.04 3.1 -3-7.3 55013 Q9NWR8

161 0.257 TRPM3 "transient receptor potential cation channel, subfamily M, member 3" 0 0.01 0-0.1 -2.5 -3-8.3 80036 Q9HCF6

162 0.257 SLC25A16 "solute carrier family 25 (mitochondrial carrier; Graves disease autoantigen), member 16" 1 0.04 0-0.54 3.1 0.9-6 8034 P16260

163 0.257 RFX4 "regulatory factor X, 4 (influences HLA class II expression)" 0 0.03 0-0.53 -2.9 -3-4.7 5992 Q33E94

164 0.257 MBD5 methyl-CpG binding domain protein 5 0 0.01 0-0.21 3.4 -0.3-5.2 55777 Q9P267

165 0.257 GRID2IP "glutamate receptor, ionotropic, delta 2 (Grid2) interacting protein" 0 0.02 0-0.75 -2.5 -3-4.8 392862 A4D2P6

166 0.256 SRCRB4D "scavenger receptor cysteine rich domain containing, group B (4 domains)" 0 0.09 0-0.61 -0.1 -3-6.6 136853 Q8WTU2

167 0.256 HIP1 huntingtin interacting protein 1 0 0.04 0-0.38 2.8 -3-6.6 3092 O00291

168 0.255 TDRP testis development related protein 0 0 0-0.1 0 -3-5.5 157695 Q86YL5

169 0.255 LRRC47 leucine rich repeat containing 47 0 0.03 0-0.25 5.2 -3-7.3 57470 Q8N1G4

170 0.255 IGFBP2 "insulin-like growth factor binding protein 2, 36kDa" 0 0 0-0.06 3.6 -3-12 3485 P18065

171 0.254 ZNF57 zinc finger protein 57 0 0.15 0-0.66 1.3 -3-3.7 126295 Q68EA5

172 0.254 GPR141 G protein-coupled receptor 141 0 0 0-0.03 -2.4 -3-5.4 353345 Q7Z602

173 0.254 DENND5A DENN/MADD domain containing 5A 0 0.02 0-0.28 4.7 -3-7.5 23258 Q6IQ26

174 0.254 CCDC108 coiled-coil domain containing 108 0 0.03 0-0.41 -2.6 -3-3.1 255101 Q6ZU64

175 0.254 BEAN1 "brain expressed, associated with NEDD4, 1" 0 0.05 0-0.74 -1.6 -3-5.3 146227 Q3B7T3

176 0.253 MLEC malectin 0 0.02 0-0.52 6.5 4.4-9.4 9761 Q14165

177 0.253 LY6G5C "lymphocyte antigen 6 complex, locus G5C" 0 0.06 0-0.49 0.7 -3-4.9 80741 Q5SRR4

178 0.253 C1orf35 chromosome 1 open reading frame 35 0 0.04 0-0.53 4.6 2.5-6.5 79169 Q9BU76

179 0.253 BRICD5 BRICHOS domain containing 5 0 0.03 0-0.42 2.7 -1.6-6 283870 Q6PL45

180 0.252 TRMT13 tRNA methyltransferase 13 homolog (S. cerevisiae) 0 0.01 0-0.13 3.5 1.1-6.1 54482 Q9NUP7

181 0.252 TPP2 tripeptidyl peptidase II 0 0.03 0-0.39 4.8 2.3-7 7174 P29144

182 0.252 TAF1L "TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 210kDa-like" 0 0.01 0-0.32 -3 -3-1.4 138474 Q8IZX4

183 0.252 SKOR2 SKI family transcriptional corepressor 2 0 0.03 0-0.64 -3 -3-5 652991 Q2VWA4

184 0.252 PRRT3 proline-rich transmembrane protein 3 0 0.01 0-0.12 0.6 -3-5 285368 Q5FWE3

185 0.252 KIF26B kinesin family member 26B 0 0.03 0-0.45 -1.2 -3-5.9 55083 Q2KJY2

186 0.252 BATF "basic leucine zipper transcription factor, ATF-like" 0 0.01 0-0.16 -0.5 -3-8.6 10538 Q16520

187 0.252 ALKBH7 "alkB, alkylation repair homolog 7 (E. coli)" 1 0.08 0-0.71 4.9 2.6-6.9 84266 Q9BT30

188 0.251 ZNF404 zinc finger protein 404 0 0.01 0-0.37 -0.1 -3-5.9 342908 Q494X3

189 0.251 PRR4 proline rich 4 (lacrimal) 0 0.01 0-0.19 3.3 -1.3-8.7 11272 Q16378

190 0.251 MACROD1 MACRO domain containing 1 1 0.11 0-0.73 4.2 -1.6-6.8 28992 Q9BQ69

191 0.251 ENDOV endonuclease V 0 0.07 0-0.58 3.9 -2.2-6.1 284131 Q8N8Q3

192 0.251 ANKEF1 ankyrin repeat and EF-hand domain containing 1 0 0.01 0-0.26 1.3 -3-5.6 63926 Q9NU02

193 0.250 ZNF853 zinc finger protein 853 0 0 0-0.06 -0.9 -3-5 54753 P0CG23

194 0.250 SCN2B "sodium channel, voltage-gated, type II, beta subunit" 0 0.01 0-0.13 -2.9 -3-2.5 6327 O60939

195 0.250 LAMB4 "laminin, beta 4" 0 0.04 0-0.51 -2.4 -3-6.8 22798 A4D0S4

196 0.250 GZMM granzyme M (lymphocyte met-ase 1) 0 0.08 0-0.56 -2.1 -3-7.6 3004 P51124

197 0.250 C8G "complement component 8, gamma polypeptide" 0 0.13 0-0.75 -1.3 -3-7.8 733 P07360

198 0.250 AGXT alanine-glyoxylate aminotransferase 1 0.06 0-0.76 -2.7 -3-6.3 189 P21549

199 0.249 SLC23A2 "solute carrier family 23 (ascorbic acid transporter), member 2" 0 0.02 0-0.61 3.4 -3-7 9962 Q9UGH3

200 0.249 OTUD3 OTU domain containing 3 0 0.07 0-0.57 2.6 0.1-5.9 23252 Q5T2D3

201 0.249 MTHFR methylenetetrahydrofolate reductase (NAD(P)H) 0 0.01 0-0.12 2.6 -1.1-6.5 4524 P42898

202 0.249 LINGO3 leucine rich repeat and Ig domain containing 3 0 0.04 0-0.37 -2.2 -3-5.1 645191 P0C6S8

203 0.249 HPGD hydroxyprostaglandin dehydrogenase 15-(NAD) 0 0.01 0-0.13 0.2 -3-10.3 3248 P15428

204 0.249 HAPLN3 hyaluronan and proteoglycan link protein 3 0 0.01 0-0.42 1.4 -3-9.4 145864 Q96S86

205 0.249 DLL4 delta-like 4 (Drosophila) 0 0.03 0-0.27 -1.7 -3-7 54567 Q9NR61

206 0.249 DCP1B decapping mRNA 1B 0 0.01 0-0.13 2.4 -3-4.8 196513 Q8IZD4

207 0.249 COL28A1 "collagen, type XXVIII, alpha 1" 0 0 0-0.04 -1.9 -3-6.7 340267 Q2UY09

208 0.248 ZSWIM5 "zinc finger, SWIM-type containing 5" 0 0.08 0-0.83 -0.8 -3-4.9 57643 Q9P217

209 0.248 SUMF1 sulfatase modifying factor 1 0 0 0-0.12 3.9 -3-6.7 285362 Q8NBK3

210 0.248 SNX24 sorting nexin 24 0 0.01 0-0.16 3.2 -3-6.4 28966 Q9Y343

211 0.248 RAB24 "RAB24, member RAS oncogene family" 1 0.05 0-0.4 4.7 2.1-7.4 53917 Q969Q5

212 0.248 CKMT2 "creatine kinase, mitochondrial 2 (sarcomeric)" 1 0.01 0-0.07 -1.9 -3-7.1 1160 P17540

213 0.247 ZNF483 zinc finger protein 483 0 0.01 0-0.09 -1.1 -3-4 158399 Q8TF39

214 0.247 SMCP sperm mitochondria-associated cysteine-rich protein 0 0 0-0.07 -3 -3-0.9 4184 P49901

215 0.247 BAG5 BCL2-associated athanogene 5 0 0.03 0-0.23 4 2-6.6 9529 Q9UL15

216 0.246 TRIM74 tripartite motif containing 74 0 0.05 0-0.5 -1.5 -3-3.5 378108 Q86UV6

217 0.246 MSC musculin 0 0.06 0-0.62 -0.1 -3-9.7 9242 O60682

218 0.246 GPR137B G protein-coupled receptor 137B 0 0.06 0-0.83 2 -3-7.7 7107 O60478

219 0.246 C5orf52 chromosome 5 open reading frame 52 0 0.03 0-0.64 -3 -3-1.7 100190949 A6NGY3

220 0.246 C11orf53 chromosome 11 open reading frame 53 0 0.03 0-0.41 -2.6 -3-8.2 341032 Q8IXP5

221 0.245 RASL11B "RAS-like, family 11, member B" 0 0.04 0-0.35 -1.2 -3-6.7 65997 Q9BPW5

222 0.245 HSPB8 heat shock 22kDa protein 8 0 0.02 0-0.23 0.8 -3-8 26353 Q9UJY1

223 0.245 CEP76 centrosomal protein 76kDa 0 0.02 0-0.59 2.9 0.8-5.3 79959 Q8TAP6

224 0.244 TMEM216 transmembrane protein 216 0 0.03 0-0.58 3.4 -3-6.3 51259 Q9P0N5

225 0.244 PLEKHH1 "pleckstrin homology domain containing, family H (with MyTH4 domain) member 1" 0 0.01 0-0.08 1.7 -3-6.8 57475 Q9ULM0

226 0.244 OR13G1 "olfactory receptor, family 13, subfamily G, member 1" 0 0.01 0-0.13 -3 -3--1.8 441933 Q8NGZ3

227 0.244 MORN1 MORN repeat containing 1 0 0.09 0-0.56 2.7 -1.3-5.8 79906 Q5T089

228 0.244 CELSR3 "cadherin, EGF LAG seven-pass G-type receptor 3" 0 0.06 0-0.44 2.1 -3-6.3 1951 Q9NYQ7

229 0.244 CAGE1 cancer antigen 1 0 0.01 0-0.13 -2.9 -3-1.5 285782 Q8TC20

230 0.243 TRIM3 tripartite motif containing 3 0 0.02 0-0.28 3.2 -1.9-8 10612 O75382

231 0.243 GALNT4 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 4 (GalNAc-T4) 0 0.05 0-0.55 1.5 -3-6.1 8693

232 0.243 CRY1 cryptochrome circadian clock 1 1 0.02 0-0.39 3.4 -3-7.6 1407 Q16526

233 0.243 COL20A1 "collagen, type XX, alpha 1" 0 0.01 0-0.23 -2.7 -3-4.5 57642 Q9P218

234 0.243 CEP128 centrosomal protein 128kDa 0 0 0-0.04 2.3 -1-7.6 145508 Q6ZU80

235 0.243 ANKK1 ankyrin repeat and kinase domain containing 1 0 0.03 0-0.32 -2.6 -3-3.4 255239 Q8NFD2

236 0.242 ZFYVE1 "zinc finger, FYVE domain containing 1" 0 0.06 0-0.6 2.9 0.1-5.1 53349 Q9HBF4

237 0.242 RGS16 regulator of G-protein signaling 16 0 0.01 0-0.14 0.7 -3-8.6 6004 O15492

238 0.242 KRTAP10-10 keratin associated protein 10-10 0 0 0-0.08 -3 -3--0.4 353333 P60014

239 0.242 HMX2 H6 family homeobox 2 0 0.01 0-0.21 -2.3 -3-6.5 3167 A2RU54

240 0.242 CDKN2AIPNL CDKN2A interacting protein N-terminal like 0 0.2 0-0.97 5.1 2.7-7.1 91368 Q96HQ2

241 0.242 ADIRF adipogenesis regulatory factor 0 0.05 0-0.37 1.7 -3-11 10974 Q15847

242 0.241 WNT8B "wingless-type MMTV integration site family, member 8B" 0 0.01 0-0.18 -2.5 -3-4.3 7479 Q93098

243 0.241 TRIM52 tripartite motif containing 52 0 0.06 0-0.43 3.4 0-6.1 84851 Q96A61

244 0.241 SNX20 sorting nexin 20 0 0.01 0-0.13 -2.1 -3-5.9 124460 Q7Z614

245 0.241 NODAL nodal growth differentiation factor 0 0.06 0-0.49 -2.6 -3-4.9 4838 Q96S42

246 0.241 LINS lines homolog (Drosophila) 0 0.02 0-0.18 3.2 0.9-6.3 55180 Q8NG48

247 0.240 TSPAN1 tetraspanin 1 0 0.09 0-0.61 2.3 -3-9.8 10103 O60635

248 0.240 TNFRSF11A "tumor necrosis factor receptor superfamily, member 11a, NFKB activator" 0 0.02 0-0.21 -0.6 -3-6.3 8792 Q9Y6Q6

249 0.240 TIGD5 tigger transposable element derived 5 0 0.09 0-0.66 2.4 -0.3-4.7 84948 Q53EQ6

250 0.240 SLC36A1 "solute carrier family 36 (proton/amino acid symporter), member 1" 0 0.03 0-0.45 2.4 -3-7 206358 Q7Z2H8

251 0.240 RNF151 ring finger protein 151 0 0.06 0-0.41 -2.9 -3-0.4 146310 Q2KHN1

252 0.240 OR6B1 "olfactory receptor, family 6, subfamily B, member 1" 0 0.04 0-0.5 -3 -3--2.5 135946 O95007

253 0.240 MLYCD malonyl-CoA decarboxylase 1 0.02 0-0.14 2.2 -3-4.8 23417 O95822

254 0.240 DNAH12 "dynein, axonemal, heavy chain 12" 0 0.01 0-0.19 -2.5 -3-4.6 201625 Q6ZR08

255 0.239 SSX2IP "synovial sarcoma, X breakpoint 2 interacting protein" 0 0.04 0-0.53 3.7 -2.9-7.1 117178 Q9Y2D8

256 0.239 OPCML opioid binding protein/cell adhesion molecule-like 0 0.02 0-0.23 -2.6 -3-4.9 4978 Q14982

257 0.239 GFRAL GDNF family receptor alpha like 0 0.01 0-0.21 -3 -3--3 389400 Q6UXV0

258 0.239 ERI3 ERI1 exoribonuclease family member 3 0 0.01 0-0.09 5.5 2.8-8.3 79033 O43414

259 0.239 CHN1 chimerin 1 0 0 0-0.11 2.1 -3-9.1 1123 P15882

260 0.239 BEST2 bestrophin 2 0 0.05 0-0.66 -2.9 -3-2.8 54831 Q8NFU1

261 0.238 PRDM7 PR domain containing 7 0 0.04 0-0.45 -2.7 -3-6.4 11105 Q9NQW5

262 0.238 NPC2 "Niemann-Pick disease, type C2" 0 0.02 0-0.19 7.2 1.2-10.9 10577 P61916

263 0.238 MTFR1L mitochondrial fission regulator 1-like 1 0.09 0-0.65 4.8 2.3-6.6 56181 Q9H019

264 0.238 LYVE1 lymphatic vessel endothelial hyaluronan receptor 1 0 0.02 0-0.28 -2.9 -3-1.7 10894 Q9Y5Y7

265 0.238 LGALS8 "lectin, galactoside-binding, soluble, 8" 0 0.01 0-0.13 5 0.1-8.4 3964 O00214

266 0.238 C6orf120 chromosome 6 open reading frame 120 0 0.03 0-0.26 3.6 -3-5.2 387263 Q7Z4R8

267 0.237 NAB1 NGFI-A binding protein 1 (EGR1 binding protein 1) 0 0.03 0-0.36 4.2 -3-7.1 4664 Q13506

268 0.237 MAGI2 "membrane associated guanylate kinase, WW and PDZ domain containing 2" 0 0.01 0-0.36 -1.4 -3-5.1 9863 Q86UL8

269 0.237 KRTAP6-2 keratin associated protein 6-2 0 0.03 0-0.24 -3 -3--2 337967 Q3LI66

270 0.237 GSC goosecoid homeobox 0 0.02 0-0.28 -2.1 -3-5.8 145258 P56915

271 0.237 GPR75-ASB3 GPR75-ASB3 readthrough 0 0.04 0-0.32 100302652 A0A0A6YYF3

272 0.237 GOLT1A golgi transport 1A 0 0 0-0.05 -0.3 -3-7 127845 Q6ZVE7

273 0.237 EHD4 EH-domain containing 4 0 0.01 0-0.16 3.9 -3-7.1 30844 Q9H223

274 0.237 CD302 CD302 molecule 0 0.08 0-0.52 0.5 -3-6.5 9936 Q8IX05

275 0.236 TMEM116 transmembrane protein 116 0 0.02 0-0.27 2.9 -0.3-6.4 89894 Q8NCL8

276 0.236 TMEM106C transmembrane protein 106C 0 0.04 0-0.33 7.2 4.2-10 79022 Q9BVX2

277 0.236 RNASE10 "ribonuclease, RNase A family, 10 (non-active)" 0 0.06 0-0.47 -2.1 -3-5 338879 Q5GAN6

278 0.236 GPBAR1 G protein-coupled bile acid receptor 1 0 0.07 0-0.68 -2.4 -3-6.8 151306 Q8TDU6

279 0.236 GOPC golgi-associated PDZ and coiled-coil motif containing 0 0.02 0-0.38 4.2 0.5-6.9 57120 Q9HD26

280 0.235 ZNF436 zinc finger protein 436 0 0.12 0-0.46 2.3 0-6.6 80818 Q9C0F3

281 0.235 NPHP3 nephronophthisis 3 (adolescent) 0 0.01 0-0.15 2.9 -2.8-5 27031 Q7Z494

282 0.235 C6orf163 chromosome 6 open reading frame 163 0 0.04 0-0.35 -0.8 -3-2.2 206412 Q5TEZ5

283 0.235 C5orf15 chromosome 5 open reading frame 15 0 0.1 0-0.59 5.5 -1.3-8.1 56951 Q8NC54

284 0.235 C15orf48 chromosome 15 open reading frame 48 1 0.01 0-0.2 1.2 -3-10.6 84419 Q9C002

285 0.234 TRIM34 tripartite motif containing 34 0 0.1 0-0.65 1.2 -3-5 53840 Q9BYJ4

286 0.234 TOR2A "torsin family 2, member A" 0 0.48 0.01-0.93 3.5 0.6-5.9 27433 Q5JU69

287 0.234 TOP1MT "topoisomerase (DNA) I, mitochondrial" 1 0.11 0-0.82 4.9 1.1-8.9 116447 Q969P6

288 0.234 SLC43A1 "solute carrier family 43 (amino acid system L transporter), member 1" 0 0.02 0-0.44 2.2 -3-7.8 8501 O75387

289 0.234 SLC22A5 "solute carrier family 22 (organic cation/carnitine transporter), member 5" 0 0.07 0-0.65 2.5 -3-6.9 6584 O76082

290 0.234 SFRP5 secreted frizzled-related protein 5 0 0.03 0-0.43 -2.4 -3-6.6 6425 Q5T4F7

291 0.234 PCP4L1 Purkinje cell protein 4 like 1 0 0.01 0-0.28 -2.4 -3-6.1 654790 A6NKN8

292 0.234 KIAA0100 KIAA0100 1 0.28 0-0.97 5.9 3.3-9.3 9703 Q14667

293 0.234 HILPDA hypoxia inducible lipid droplet-associated 0 0 0-0.17 4.1 0.9-7.7 29923 Q9Y5L2

294 0.234 CD7 CD7 molecule 0 0.11 0-0.68 -1.9 -3-9.4 924 P09564

295 0.234 AKR1B15 "aldo-keto reductase family 1, member B15" 0 0.01 0-0.22 -2.1 -3-6.5 441282 C9JRZ8

296 0.234 ACSBG1 acyl-CoA synthetase bubblegum family member 1 0 0.02 0-0.21 -2.1 -3-6.3 23205 Q96GR2

297 0.233 ZNF786 zinc finger protein 786 0 0.01 0-0.14 2.1 -0.7-4.3 136051 Q8N393

298 0.233 WDR31 WD repeat domain 31 0 0 0-0.08 0.3 -3-3 114987 Q8NA23

299 0.233 SAMD15 sterile alpha motif domain containing 15 0 0.07 0-0.6 -0.5 -3-3.8 161394 Q9P1V8

300 0.233 LYG2 lysozyme G-like 2 0 0.02 0-0.34 -2.6 -3-3.6 254773 Q86SG7

Rank Corr Symbol Description MitoCarta2.0 CDM meanD CDM range TPM mean TPM range Entrez UniProt

17375 -0.130 RTFDC1 replication termination factor 2 domain containing 1 0 0.75 0.02-1 6.7 4.9-8.8 51507 Q9BY42

17376 -0.130 PGBD3 piggyBac transposable element derived 3 0 0.16 0-0.77 0.6 -3-4.8 267004

17377 -0.130 NACA2 nascent polypeptide-associated complex alpha subunit 2 0 0.16 0-0.73 -0.2 -3-2.4 342538 Q9H009

17378 -0.130 FAM177B "family with sequence similarity 177, member B" 0 0.03 0-0.38 -2.8 -3-5.3 400823 A6PVY3

17379 -0.130 CPAMD8 "C3 and PZP-like, alpha-2-macroglobulin domain containing 8" 0 0.39 0.01-0.99 -1.2 -3-6.3 27151 Q8IZJ3

17380 -0.131 TMCO5A transmembrane and coiled-coil domains 5A 0 0.14 0-0.7 -3 -3--1.3 145942 Q8N6Q1

17381 -0.131 NPEPPS aminopeptidase puromycin sensitive 0 0.58 0.02-0.99 6.1 2.7-8.6 9520 P55786

17382 -0.131 NOL12 nucleolar protein 12 0 0.76 0.01-0.99 79159 Q9UGY1

17383 -0.131 IL12RB2 "interleukin 12 receptor, beta 2" 0 0.2 0-0.93 -1.9 -3-6.8 3595 Q99665

17384 -0.131 CUBN cubilin (intrinsic factor-cobalamin receptor) 0 0.09 0-0.61 -2.1 -3-6.2 8029 O60494

17385 -0.131 CPQ carboxypeptidase Q 0 0.15 0-0.79 1.2 -3-6.7 10404 Q9Y646

17386 -0.131 CLP1 cleavage and polyadenylation factor I subunit 1 0 0.96 0.52-1 4 1.5-6.1 10978 Q92989

17387 -0.131 CAB39 calcium binding protein 39 0 0.2 0-0.97 5 2.7-7.2 51719 Q9Y376

17388 -0.132 ZC3H18 zinc finger CCCH-type containing 18 0 0.79 0.05-1 5 2.1-7 124245 Q86VM9

17389 -0.132 TARS2 "threonyl-tRNA synthetase 2, mitochondrial (putative)" 1 0.83 0.17-1 4.7 2.7-8.9 80222 Q9BW92

17390 -0.132 SLC7A8 "solute carrier family 7 (amino acid transporter light chain, L system), member 8" 0 0.05 0-0.37 0.5 -3-9.1 23428 Q9UHI5

17391 -0.132 PSMD4 "proteasome (prosome, macropain) 26S subunit, non-ATPase, 4" 0 0.99 0.71-1 7.6 5.8-11.1 5710 P55036

17392 -0.132 MPHOSPH6 M-phase phosphoprotein 6 0 0.27 0-0.98 5.3 1.8-8.1 10200 Q99547

17393 -0.132 GABPA "GA binding protein transcription factor, alpha subunit 60kDa" 0 0.48 0.01-0.98 3.5 1.2-6.1 2551 Q06546

17394 -0.133 WDHD1 WD repeat and HMG-box DNA binding protein 1 0 0.92 0.17-1 4.1 0.7-6.5 11169 O75717

17395 -0.133 USP37 ubiquitin specific peptidase 37 0 0.58 0.02-0.99 2.3 -1.9-4.9 57695 Q86T82

17396 -0.133 TMEM167A transmembrane protein 167A 0 0.33 0-1 5.9 4-8.4 153339 Q8TBQ9

17397 -0.133 POLR2H polymerase (RNA) II (DNA directed) polypeptide H 0 0.88 0.23-1 6.8 5.1-8.5 5437 P52434

17398 -0.133 NRF1 nuclear respiratory factor 1 0 0.88 0-1 3.5 1.5-5 4899 Q16656

17399 -0.133 MTBP "Mdm2, transformed 3T3 cell double minute 2, p53 binding protein (mouse) binding protein, 104kDa" 0 0.99 0.73-1 3.1 -0.3-6.6 27085 Q96DY7

17400 -0.133 LCE6A late cornified envelope 6A 0 0.08 0-0.61 -3 -3-3.2 448835 A0A183

17401 -0.134 XRN1 5'-3' exoribonuclease 1 0 0.54 0-1 3 0.1-5.8 54464 Q8IZH2

17402 -0.134 TTK TTK protein kinase 0 0.83 0.13-1 4.2 -0.1-6.7 7272 P33981

17403 -0.134 TRAPPC11 trafficking protein particle complex 11 0 0.91 0.25-1 3.7 1.6-5.8 60684 Q7Z392

17404 -0.134 SEC16A SEC16 homolog A (S. cerevisiae) 0 0.69 0.03-1 5.3 2.8-7.9 9919 O15027

17405 -0.134 NRBF2 nuclear receptor binding factor 2 0 0.25 0-0.86 4 2.3-7.4 29982 Q96F24

17406 -0.134 HGS hepatocyte growth factor-regulated tyrosine kinase substrate 0 0.7 0.02-0.99 6.3 4.3-8 9146 O14964

17407 -0.134 DET1 de-etiolated homolog 1 (Arabidopsis) 0 0.34 0-0.97 1.6 -3-3.9 55070 Q7L5Y6

17408 -0.135 PRPF40A PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) 0 0.86 0.13-1 5.9 2.4-7.3 55660 O75400

17409 -0.135 NCBP1 "nuclear cap binding protein subunit 1, 80kDa" 0 0.96 0.55-1 4.4 2.1-6.6 4686 Q09161

17410 -0.135 CYP4F3 "cytochrome P450, family 4, subfamily F, polypeptide 3" 0 0.06 0-0.45 -1.2 -3-7.8 4051 Q08477

17411 -0.135 CTAGE9 "CTAGE family, member 9" 0 0.39 0.01-0.85 -2.8 -3-0.7 643854 A4FU28

17412 -0.135 CEACAM8 carcinoembryonic antigen-related cell adhesion molecule 8 0 0.09 0-0.55 -3 -3-3.5 1088 P31997

17413 -0.136 NEK7 NIMA-related kinase 7 0 0.05 0-0.56 4.3 -1.1-8.7 140609 Q8TDX7

17414 -0.136 LGALS14 "lectin, galactoside-binding, soluble, 14" 0 0.13 0-0.93 -2.7 -3-7.8 56891 Q8TCE9

17415 -0.136 GOLGA6L6 golgin A6 family-like 6 0 0.43 0.01-0.92 727832 A8MZA4

17416 -0.136 GINS3 GINS complex subunit 3 (Psf3 homolog) 0 0.94 0.32-1 3.7 -0.1-6.3 64785 Q9BRX5

17417 -0.136 ANAPC2 anaphase promoting complex subunit 2 0 0.98 0.67-1 4.8 1.6-6.8 29882 Q9UJX6

17418 -0.137 YEATS2 YEATS domain containing 2 0 0.69 0.03-0.99 4.4 1.8-6.9 55689 Q9ULM3

17419 -0.137 RBMXL1 "RNA binding motif protein, X-linked-like 1" 0 0.85 0.12-1 2.8 0.2-5.2 494115 Q96E39

17420 -0.137 NUDT21 nudix (nucleoside diphosphate linked moiety X)-type motif 21 0 0.99 0.77-1 6.4 4-8.5 11051 O43809

17421 -0.137 NPLOC4 nuclear protein localization 4 homolog (S. cerevisiae) 0 0.93 0.07-1 5.8 3.6-7.6 55666 Q8TAT6

17422 -0.137 NOL10 nucleolar protein 10 0 0.98 0.56-1 4.4 1.8-6.1 79954 Q9BSC4

17423 -0.137 KRAS Kirsten rat sarcoma viral oncogene homolog 0 0.44 0-1 4 1.6-10.6 3845 P01116

17424 -0.137 HNRNPL heterogeneous nuclear ribonucleoprotein L 0 0.79 0.02-1 8.2 6-9.5 3191 P14866

17425 -0.137 ANAPC1 anaphase promoting complex subunit 1 0 0.87 0.02-1 4.5 2.3-6.5 64682 Q9H1A4

17426 -0.137 AHCTF1 AT hook containing transcription factor 1 0 0.91 0.16-1 5 1.7-7.2 25909 Q8WYP5

17427 -0.138 SART3 squamous cell carcinoma antigen recognized by T cells 3 0 0.9 0.09-1 5.3 3-6.6 9733 Q15020

17428 -0.138 PSMD6 "proteasome (prosome, macropain) 26S subunit, non-ATPase, 6" 0 0.98 0.76-1 6.4 3.6-10.6 9861 Q15008

17429 -0.138 GRK7 G protein-coupled receptor kinase 7 0 0.07 0-0.58 -3 -3--0.4 131890 Q8WTQ7

17430 -0.139 TIAF1 TGFB1-induced anti-apoptotic factor 1 0 0.09 0-0.64 2.4 -1.4-7.5 9220 O95411

17431 -0.139 IFNA14 "interferon, alpha 14" 0 0.15 0-0.56 -3 -3-0.9 3448 P01570

17432 -0.139 GTF2B general transcription factor IIB 0 0.98 0.73-1 5 3.1-7 2959 Q00403

17433 -0.139 CSE1L CSE1 chromosome segregation 1-like (yeast) 0 0.94 0.26-1 6.4 3.8-8.7 1434 P55060

17434 -0.140 STRAP serine/threonine kinase receptor associated protein 0 0.78 0.01-1 6.9 4.5-11.1 11171 Q9Y3F4

17435 -0.140 SNRNP27 small nuclear ribonucleoprotein 27kDa (U4/U6.U5) 0 0.96 0.65-1 5.6 3.9-7.3 11017 Q8WVK2

17436 -0.140 METTL3 methyltransferase like 3 0 0.83 0.11-1 5.6 2.9-7.8 56339 Q86U44

17437 -0.140 KMT2B lysine (K)-specific methyltransferase 2B 0 0.29 0-0.93 2.4 -2.7-5.1 9757 Q9UMN6

17438 -0.140 AMER2 APC membrane recruitment protein 2 0 0.19 0-0.76 -2.6 -3-7 219287 Q8N7J2

17439 -0.141 MRPL45 mitochondrial ribosomal protein L45 1 0.72 0.02-1 84311 B4DEF8

17440 -0.141 MIS18A MIS18 kinetochore protein A 0 0.98 0.53-1 4.7 1.7-7 54069 Q9NYP9

17441 -0.141 MED8 mediator complex subunit 8 0 0.98 0.55-1 5.1 3.1-7 112950 Q96G25

17442 -0.141 H3F3C "H3 histone, family 3C" 0 0.26 0.01-0.83 -0.8 -3-4.1 440093 Q6NXT2

17443 -0.141 EPB41L5 erythrocyte membrane protein band 4.1 like 5 0 0.05 0-0.54 2.7 -3-6.6 57669 Q9HCM4

17444 -0.141 EIF3D "eukaryotic translation initiation factor 3, subunit D" 0 0.96 0.32-1 7.9 6.1-9.5 8664 O15371

17445 -0.141 COPS2 COP9 signalosome subunit 2 0 0.72 0.06-0.99 5.6 3.1-7.4 9318 P61201

17446 -0.141 CASQ2 calsequestrin 2 (cardiac muscle) 0 0.14 0-0.77 -2.8 -3-4.6 845 O14958

17447 -0.142 UBAP1 ubiquitin associated protein 1 0 0.81 0.15-1 4.7 2.3-7.4 51271 Q9NZ09

17448 -0.142 RPAP1 RNA polymerase II associated protein 1 0 0.97 0.54-1 4 1.4-6.4 26015 Q9BWH6

17449 -0.142 PPP1R8 "protein phosphatase 1, regulatory subunit 8" 0 0.96 0.33-1 5.1 3.1-6.6 5511 Q12972

17450 -0.142 COG2 component of oligomeric golgi complex 2 0 0.69 0.08-0.98 4 1.7-6 22796 Q14746

17451 -0.143 SDAD1 SDA1 domain containing 1 0 0.63 0.01-0.98 4.5 2.3-6.1 55153 Q9NVU7

17452 -0.143 SAMD4B sterile alpha motif domain containing 4B 0 0.31 0-0.95 6.2 3.8-9.7 55095 Q5PRF9

17453 -0.143 RPL27 ribosomal protein L27 0 0.99 0.83-1 11.2 8.5-13.5 6155 P61353

17454 -0.143 CHMP2A charged multivesicular body protein 2A 0 0.98 0.74-1 6.9 4.5-9.4 27243 O43633

17455 -0.144 SLC9B1 "solute carrier family 9, subfamily B (NHA1, cation proton antiporter 1), member 1" 0 0.45 0.03-0.92 -1.8 -3-3.6 150159 Q4ZJI4

17456 -0.144 SAE1 SUMO1 activating enzyme subunit 1 0 0.98 0.35-1 7.2 4.6-9.3 10055 Q9UBE0

17457 -0.144 RNASE13 "ribonuclease, RNase A family, 13 (non-active)" 0 0.11 0-0.62 -3 -3--0.7 440163 Q5GAN3

17458 -0.144 POLD2 "polymerase (DNA directed), delta 2, accessory subunit" 0 0.83 0.13-0.99 7.8 5.2-9.4 5425 P49005

17459 -0.144 OR4D2 "olfactory receptor, family 4, subfamily D, member 2" 0 0.15 0-0.76 -3 -3--2.7 124538 P58180

17460 -0.144 KRT79 keratin 79 0 0.2 0.01-0.66 -2.6 -3-7 338785 Q5XKE5

17461 -0.145 XAB2 XPA binding protein 2 0 0.99 0.84-1 4.8 1.7-6.9 56949 Q9HCS7

17462 -0.145 LRRC15 leucine rich repeat containing 15 0 0.24 0-0.77 -2.1 -3-6.7 131578 Q8TF66

17463 -0.146 STIL SCL/TAL1 interrupting locus 0 0.68 0-1 3.5 0.1-6.2 6491 Q15468

17464 -0.146 RTTN rotatin 0 0.75 0.06-1 3.2 0.5-7.2 25914 Q86VV8

17465 -0.146 PIK3CA "phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha" 0 0.36 0-0.99 3.3 0.6-5.9 5290 P42336

17466 -0.146 LSM3 "LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae)" 0 0.94 0.49-1 4.2 1.8-6.2 27258 P62310

17467 -0.146 FRG2C "FSHD region gene 2 family, member C" 0 0.26 0-0.87 -2.9 -3-7.7 100288801 A6NGY1

17468 -0.146 AP2S1 "adaptor-related protein complex 2, sigma 1 subunit" 0 0.76 0.01-1 7.4 5.1-9.2 1175 P53680

17469 -0.147 TSG101 tumor susceptibility 101 0 0.86 0.24-1 6 3.9-7.6 7251 Q99816

17470 -0.147 SENP6 SUMO1/sentrin specific peptidase 6 0 0.94 0.59-1 4.9 1.4-7 26054 Q9GZR1

17471 -0.147 NEDD8 "neural precursor cell expressed, developmentally down-regulated 8" 0 0.98 0.72-1 8.3 5.1-9.7 4738 Q15843

17472 -0.147 CDT1 chromatin licensing and DNA replication factor 1 0 0.97 0.64-1 4.5 -0.5-7.7 81620 Q9H211

17473 -0.148 VPS28 vacuolar protein sorting 28 homolog (S. cerevisiae) 0 0.88 0-1 6.6 4.2-8.8 51160 Q9UK41

17474 -0.148 OR8I2 "olfactory receptor, family 8, subfamily I, member 2" 0 0.15 0-0.58 -3 -3--1.9 120586 Q8N0Y5

17475 -0.148 GAPDH glyceraldehyde-3-phosphate dehydrogenase 1 0.94 0.39-1 11.9 9.1-14.3 2597 P04406

17476 -0.149 WDR12 WD repeat domain 12 0 0.95 0.24-1 5.8 3.6-8 55759 Q9GZL7

17477 -0.149 PI4KA "phosphatidylinositol 4-kinase, catalytic, alpha" 1 0.9 0.34-1 4.9 2.5-10.5 5297 P42356

17478 -0.149 ORC4 "origin recognition complex, subunit 4" 0 0.55 0.02-0.98 4.6 1.9-6.7 5000 O43929

17479 -0.149 MIS12 MIS12 kinetochore complex component 0 0.74 0.02-1 4 1.5-6.1 79003 Q9H081

17480 -0.149 EXOSC5 exosome component 5 0 0.88 0.13-1 5.2 2.4-7.2 56915 Q9NQT4

17481 -0.150 C3orf17 chromosome 3 open reading frame 17 0 0.96 0.17-1 4.6 2.8-6.1 25871 Q6NW34

17482 -0.151 RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated) 0 0.14 0.01-0.82 -1 -3-7.6 10125 O95267

17483 -0.151 PUF60 poly-U binding splicing factor 60KDa 0 0.99 0.87-1 7.2 5-9.2 22827 Q9UHX1

17484 -0.151 PPAN peter pan homolog (Drosophila) 0 0.92 0.18-1 5.6 3.2-9.1 56342

17485 -0.151 HDC histidine decarboxylase 0 0.06 0-0.37 -2.6 -3-10.1 3067 P19113

17486 -0.151 ESPL1 extra spindle pole bodies homolog 1 (S. cerevisiae) 0 1 0.79-1 4 -0.3-6.6 9700 Q14674

17487 -0.151 DCLK1 doublecortin-like kinase 1 0 0.09 0-0.77 -0.6 -3-9.2 9201 O15075

17488 -0.152 TRAIP TRAF interacting protein 0 0.89 0.19-1 3.7 -0.5-5.5 10293 Q9BWF2

17489 -0.152 NOP58 NOP58 ribonucleoprotein 0 0.97 0.39-1 6.6 3.8-8.2 51602 Q9Y2X3

17490 -0.152 DPPA3 developmental pluripotency associated 3 0 0.32 0.01-0.85 -3 -3-3.9 359787 Q6W0C5

17491 -0.152 C9orf78 chromosome 9 open reading frame 78 0 0.69 0.03-0.99 6.4 4-8.2 51759 Q9NZ63

17492 -0.152 ATP2A2 "ATPase, Ca++ transporting, cardiac muscle, slow twitch 2" 0 0.98 0.33-1 6.9 3.6-8.8 488 P16615

17493 -0.153 TXNL4B thioredoxin-like 4B 0 0.71 0.03-0.99 3.6 1.3-6.1 54957 Q9NX01

17494 -0.153 SMC2 structural maintenance of chromosomes 2 0 0.99 0.58-1 4.3 0.4-7.7 10592 O95347

17495 -0.153 MED6 mediator complex subunit 6 0 0.92 0.12-1 4.9 3.1-6.7 10001 O75586

17496 -0.153 CYFIP1 cytoplasmic FMR1 interacting protein 1 0 0.43 0-0.94 23191 Q7L576

17497 -0.154 USP8 ubiquitin specific peptidase 8 0 0.82 0.05-1 4.5 1.7-6.2 9101 P40818

17498 -0.154 PPP2R3C "protein phosphatase 2, regulatory subunit B'', gamma" 0 0.68 0.01-1 4.4 1.9-7.6 55012 Q969Q6

17499 -0.154 PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2 0 0.76 0.07-1 4.8 2.6-7.4 23759 Q13356

17500 -0.154 POLR1C "polymerase (RNA) I polypeptide C, 30kDa" 0 1 0.92-1 5.7 3.6-8.4 9533 O15160

17501 -0.154 LSM6 "LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae)" 0 0.86 0.08-1 6.2 4-8.7 11157 P62312

17502 -0.154 GTF2A2 "general transcription factor IIA, 2, 12kDa" 0 0.96 0.36-1 6.6 4.3-8.6 2958 P52657

17503 -0.154 CDH15 "cadherin 15, type 1, M-cadherin (myotubule)" 0 0.22 0-0.77 -2.3 -3-7.2 1013 P55291

17504 -0.155 TCEB1 "transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C)" 0 0.42 0-0.98 6.9 4.9-9.3 6921 Q15369

17505 -0.155 LAIR1 leukocyte-associated immunoglobulin-like receptor 1 0 0.15 0-0.87 -1.6 -3-9.3 3903 Q6GTX8

17506 -0.155 CRCP CGRP receptor component 0 0.98 0.39-1 5 2.6-6.7 27297 O75575

17507 -0.155 BANP BTG3 associated nuclear protein 0 0.86 0.13-1 3.4 1.4-7.3 54971 Q8N9N5

17508 -0.156 TRPM1 "transient receptor potential cation channel, subfamily M, member 1" 0 0.05 0-0.46 -2.7 -3-9.6 4308 Q7Z4N2

17509 -0.156 TAF7 "TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 55kDa" 0 0.92 0.44-1 6.2 3.2-7.8 6879 Q15545

17510 -0.156 POLR2F polymerase (RNA) II (DNA directed) polypeptide F 0 0.92 0.28-1 6.8 3.3-9.7 5435 P61218

17511 -0.156 NUP93 nucleoporin 93kDa 0 0.99 0.87-1 5.7 2.6-9.2 9688 Q8N1F7

17512 -0.157 ZCRB1 zinc finger CCHC-type and RNA binding motif 1 0 0.75 0.02-1 5.9 3.5-7.8 85437 Q8TBF4

17513 -0.157 SKIV2L2 superkiller viralicidic activity 2-like 2 (S. cerevisiae) 0 0.98 0.7-1 5.5 3-7 23517 P42285

17514 -0.157 MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) 0 0.77 0.03-1 5.8 2-7.9 4085 Q13257

17515 -0.157 ISCU iron-sulfur cluster assembly enzyme 1 0.97 0.52-1 6.3 4.7-8.6 23479 Q9H1K1

17516 -0.158 ATR ataxia telangiectasia and Rad3 related 0 0.82 0.13-1 4.5 2.2-6.5 545 Q13535

17517 -0.159 PTPN23 "protein tyrosine phosphatase, non-receptor type 23" 0 0.91 0.07-1 3.9 1.1-5.6 25930 Q9H3S7

17518 -0.159 PRPF38A pre-mRNA processing factor 38A 0 0.98 0.67-1 4.9 2.4-6.6 84950 Q8NAV1

17519 -0.159 MAST3 microtubule associated serine/threonine kinase 3 0 0.26 0.01-0.82 1.5 -3-4.3 23031 O60307

17520 -0.159 CDC23 cell division cycle 23 0 0.99 0.85-1 4.8 2.7-6.4 8697 Q9UJX2

17521 -0.159 CCDC174 coiled-coil domain containing 174 0 0.82 0.03-1 3.1 1.1-5.2 51244 Q6PII3

17522 -0.160 TICRR TOPBP1-interacting checkpoint and replication regulator 0 0.95 0.62-1 3 -0.7-5.4 90381 Q7Z2Z1

17523 -0.160 PSMD11 "proteasome (prosome, macropain) 26S subunit, non-ATPase, 11" 0 0.92 0.13-1 6.6 4.3-8.5 5717 O00231

17524 -0.161 SRP68 signal recognition particle 68kDa 0 0.78 0.05-1 6 4.1-7.9 6730 Q9UHB9

17525 -0.161 AARS2 "alanyl-tRNA synthetase 2, mitochondrial" 1 0.7 0.02-1 3.4 -0.4-6.7 57505 Q5JTZ9

17526 -0.162 ARIH1 ariadne RBR E3 ubiquitin protein ligase 1 0 0.95 0.1-1 4.3 2.6-6.1 25820 Q9Y4X5

17527 -0.163 MCM5 minichromosome maintenance complex component 5 0 0.98 0.43-1 5.7 1.8-8 4174 P33992

17528 -0.163 CDC45 cell division cycle 45 0 1 0.9-1 5.1 0.4-8 8318 O75419

17529 -0.164 URB1 URB1 ribosome biogenesis 1 homolog (S. cerevisiae) 0 0.98 0.7-1 3.3 0.5-6.6 9875 O60287

17530 -0.164 UPF1 UPF1 regulator of nonsense transcripts homolog (yeast) 0 0.92 0.29-1 5.1 2.7-6.8 5976 Q92900

17531 -0.164 GTF3C1 "general transcription factor IIIC, polypeptide 1, alpha 220kDa" 0 0.73 0.06-0.98 5.3 3.4-7.7 2975 Q12789

17532 -0.165 PSMA3 "proteasome (prosome, macropain) subunit, alpha type, 3" 0 1 0.92-1 7.5 5.1-9.2 5684 P25788

17533 -0.165 PSAT1 phosphoserine aminotransferase 1 0 0.4 0.03-0.97 6 -2.1-9.6 29968 Q9Y617

17534 -0.165 PRPF38B pre-mRNA processing factor 38B 0 0.98 0.21-1 5.5 2.1-7.5 55119 Q5VTL8

17535 -0.165 PDRG1 p53 and DNA-damage regulated 1 0 0.99 0.69-1 5 2.5-7.3 81572 Q9NUG6

17536 -0.165 ACTR10 actin-related protein 10 homolog (S. cerevisiae) 0 0.83 0.08-1 5.2 3.1-7.5 55860 Q9NZ32

17537 -0.167 PSMC5 "proteasome (prosome, macropain) 26S subunit, ATPase, 5" 0 0.97 0.49-1 7.5 5.5-10.5 5705 P62195

17538 -0.168 TUBGCP4 "tubulin, gamma complex associated protein 4" 0 0.89 0.06-1 4.1 1.9-5.9 27229 Q9UGJ1

17539 -0.168 TBCD tubulin folding cofactor D 0 0.88 0.07-1 5.4 2.6-8.3 6904 Q9BTW9

17540 -0.168 ECD ecdysoneless homolog (Drosophila) 0 0.96 0.23-1 4.1 1.8-5.9 11319 O95905

17541 -0.170 VPS25 vacuolar protein sorting 25 homolog (S. cerevisiae) 0 1 0.82-1 6.2 3.8-8.3 84313 Q9BRG1

17542 -0.170 SRRM1 serine/arginine repetitive matrix 1 0 0.9 0.2-1 5.9 3.5-8 10250 Q8IYB3

17543 -0.170 RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) 0 0.94 0.16-1 5.2 2.5-7.4 23212 Q15050

17544 -0.170 PSMD2 "proteasome (prosome, macropain) 26S subunit, non-ATPase, 2" 0 0.91 0.12-1 8.5 6-11.5 5708 Q13200

17545 -0.170 KARS lysyl-tRNA synthetase 1 0.99 0.59-1 7 4.3-8.9 3735 Q15046

17546 -0.171 WDR75 WD repeat domain 75 0 0.98 0.66-1 5 3.1-9 84128 Q8IWA0

17547 -0.171 NSMCE1 non-SMC element 1 homolog (S. cerevisiae) 0 0.8 0.08-1 5.7 3.4-8.4 197370 Q8WV22

17548 -0.171 FIP1L1 factor interacting with PAPOLA and CPSF1 0 0.85 0.04-1 5.8 3.8-8.3 81608 Q6UN15

17549 -0.172 IFITM2 interferon induced transmembrane protein 2 0 0.76 0.13-1 4.8 -3-11.3 10581 Q01629

17550 -0.172 CSTF3 "cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa" 0 0.88 0.12-1 5.3 3.5-7.7 1479 Q12996

17551 -0.173 RPA2 "replication protein A2, 32kDa" 0 0.96 0.06-1 5.7 3.5-7.8 6118 P15927

17552 -0.174 SHQ1 "SHQ1, H/ACA ribonucleoprotein assembly factor" 0 0.91 0.26-1 3.3 0.5-7.2 55164 Q6PI26

17553 -0.174 RBM14 RNA binding motif protein 14 0 0.92 0.09-1 5.5 3-7 10432 A0A0S2Z4Z0

17554 -0.174 PSMC3 "proteasome (prosome, macropain) 26S subunit, ATPase, 3" 0 0.97 0.68-1 7.8 5.6-9.7 5702 P17980

17555 -0.175 TPTE2 transmembrane phosphoinositide 3-phosphatase and tensin homolog 2 0 0.19 0-0.58 -2.8 -3-6.8 93492 Q6XPS3

17556 -0.176 PRPF6 pre-mRNA processing factor 6 0 0.97 0.57-1 5.9 2.9-8.2 24148 O94906

17557 -0.176 OR4D1 "olfactory receptor, family 4, subfamily D, member 1" 0 0.16 0-0.56 -3 -3--2.1 26689 Q15615

17558 -0.176 CDC20 cell division cycle 20 0 0.99 0.86-1 6.9 2.7-9.6 991 Q12834

17559 -0.176 CASC5 cancer susceptibility candidate 5 0 0.61 0.05-0.99 3.4 -0.6-6.2 57082 Q8NG31

17560 -0.177 ZMAT5 "zinc finger, matrin-type 5" 0 0.95 0.4-1 4 1.5-6 55954 Q9UDW3

17561 -0.177 POLR2B "polymerase (RNA) II (DNA directed) polypeptide B, 140kDa" 0 0.99 0.8-1 6 3.6-9.7 5431 P30876

17562 -0.177 NCAPG "non-SMC condensin I complex, subunit G" 0 1 0.77-1 4.6 0.3-6.5 64151 Q9BPX3

17563 -0.177 CPSF1 "cleavage and polyadenylation specific factor 1, 160kDa" 0 0.98 0.63-1 6.3 3.5-8.5 29894 Q10570

17564 -0.178 RNPC3 "RNA-binding region (RNP1, RRM) containing 3" 0 0.99 0.8-1 3.6 1.1-6 55599 Q96LT9

17565 -0.178 GTF2E1 "general transcription factor IIE, polypeptide 1, alpha 56kDa" 0 0.93 0.26-1 3.5 1.5-5.4 2960 P29083

17566 -0.178 BMS1 BMS1 ribosome biogenesis factor 0 0.95 0.01-1 4 1.7-5.8 9790 Q14692

17567 -0.179 NOP56 NOP56 ribonucleoprotein 0 0.97 0.55-1 8.4 5.4-10.3 10528 O00567

17568 -0.179 GINS1 GINS complex subunit 1 (Psf1 homolog) 0 0.99 0.69-1 4.2 -0.3-6.2 9837 Q14691

17569 -0.180 EIF4A3 eukaryotic translation initiation factor 4A3 0 0.95 0.11-1 6.6 4-9 9775 P38919

17570 -0.181 URI1 "URI1, prefoldin-like chaperone" 0 0.91 0.09-1 5.5 3.4-9.7 8725 O94763

17571 -0.182 OSGEP O-sialoglycoprotein endopeptidase 0 0.98 0.44-1 4.9 2-7 55644 Q9NPF4

17572 -0.183 TMA16 translation machinery associated 16 homolog (S. cerevisiae) 0 0.9 0.26-1 5.2 1.4-7.5 55319 Q96EY4

17573 -0.184 KIN "KIN, antigenic determinant of recA protein homolog (mouse)" 0 0.93 0.15-1 3.8 1.3-5.3 22944 O60870

17574 -0.185 RPL18A ribosomal protein L18a 0 0.96 0.36-1 10.8 8.4-12.7 6142 Q02543

17575 -0.185 DGCR14 DiGeorge syndrome critical region gene 14 0 0.85 0.05-1 3.5 1.3-5.5 8220 Q96DF8

17576 -0.185 CHCHD4 coiled-coil-helix-coiled-coil-helix domain containing 4 1 0.91 0.25-1 4.2 1.1-6.5 131474 Q8N4Q1

17577 -0.185 BORA "bora, aurora kinase A activator" 0 0.93 0.12-1 3.6 0.5-6 79866 Q6PGQ7

17578 -0.186 GGTLC2 gamma-glutamyltransferase light chain 2 0 0.83 0.06-0.99 -2.9 -3-2.7 91227 Q14390

17579 -0.186 CDCA8 cell division cycle associated 8 0 1 0.84-1 5.3 1.3-9.4 55143 Q53HL2

17580 -0.187 SRSF3 serine/arginine-rich splicing factor 3 0 0.99 0.74-1 7.3 5.4-8.6 6428 P84103

17581 -0.188 PCNA proliferating cell nuclear antigen 0 1 0.86-1 7.9 4-10.1 5111 P12004

17582 -0.188 MPP3 "membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)" 0 0.27 0.01-0.74 2.4 -3-6.5 4356 Q13368

17583 -0.189 RPS13 ribosomal protein S13 0 0.99 0.24-1 10.3 7.8-11.9 6207 P62277

17584 -0.190 RFT1 RFT1 homolog (S. cerevisiae) 0 0.91 0.11-1 4.5 1.7-6.5 91869 Q96AA3

17585 -0.190 PCID2 PCI domain containing 2 0 0.9 0.23-1 5.6 3.3-8 55795 Q5JVF3

17586 -0.190 CTNNBL1 "catenin, beta like 1" 0 0.87 0.02-1 5.7 3.2-8.4 56259 Q8WYA6

17587 -0.190 ANKRD49 ankyrin repeat domain 49 0 0.59 0-1 3.7 0.9-6.4 54851 Q8WVL7

17588 -0.191 TXNL4A thioredoxin-like 4A 0 1 0.9-1 6 3.6-8.5 10907 P83876

17589 -0.191 SF3B4 "splicing factor 3b, subunit 4, 49kDa" 0 1 0.91-1 5.9 3.7-7.9 10262 Q15427

17590 -0.191 DDOST dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic) 0 0.88 0.09-1 7.9 4.6-10.1 1650 P39656

17591 -0.192 SLC35G3 "solute carrier family 35, member G3" 0 0.29 0-0.81 -3 -3-0 146861 Q8N808

17592 -0.192 NPAT "nuclear protein, ataxia-telangiectasia locus" 0 0.82 0.03-0.99 2.7 -0.5-5.3 4863 Q14207

17593 -0.193 UBA3 ubiquitin-like modifier activating enzyme 3 0 0.88 0.09-1 5.4 2.9-7.6 9039 Q8TBC4

17594 -0.193 ALG1L "ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase-like" 0 0.75 0.1-0.98 -0.5 -3-6.5 200810 Q6GMV1

17595 -0.194 UGT2B11 "UDP glucuronosyltransferase 2 family, polypeptide B11" 0 0.2 0-0.88 -2.8 -3-6.7 10720 O75310

17596 -0.194 TRAPPC4 trafficking protein particle complex 4 0 0.97 0.46-1 6.2 3.8-8.9 51399 Q9Y296

17597 -0.194 PRPF4 pre-mRNA processing factor 4 0 0.9 0.22-1 4.9 2.2-6.8 9128 O43172

17598 -0.196 SF3A2 "splicing factor 3a, subunit 2, 66kDa" 0 0.99 0.84-1 5.8 2.5-7.8 8175 Q15428

17599 -0.197 GOLGA8N "golgin A8 family, member N" 0 0.38 0.01-0.85 0.6 -3-8 643699 F8WBI6

17600 -0.199 PSMB3 "proteasome (prosome, macropain) subunit, beta type, 3" 0 1 0.96-1 5691 P49720

17601 -0.199 POU5F1B POU class 5 homeobox 1B 0 0.67 0.09-0.95 -2.2 -3-4.6 5462 Q06416

17602 -0.199 EXOSC7 exosome component 7 0 0.84 0.07-0.99 5.8 3.6-8.1 23016 Q15024

17603 -0.202 SRSF7 serine/arginine-rich splicing factor 7 0 0.99 0.9-1 7.5 4.6-8.9 6432 Q16629

17604 -0.202 PPIL1 peptidylprolyl isomerase (cyclophilin)-like 1 0 0.72 0.02-1 5.3 3-7.2 51645 Q9Y3C6

17605 -0.202 CCT3 "chaperonin containing TCP1, subunit 3 (gamma)" 0 1 0.9-1 8.2 5.9-10.1 7203 P49368

17606 -0.202 BUB1B BUB1 mitotic checkpoint serine/threonine kinase B 0 0.98 0.48-1 5.5 1.5-8 701 O60566

17607 -0.203 THOC7 THO complex 7 homolog (Drosophila) 0 0.96 0.49-1 6 3.5-8.6 80145 Q6I9Y2

17608 -0.203 SNRPB small nuclear ribonucleoprotein polypeptides B and B1 0 1 0.9-1 8.2 6.3-9.8 6628 P14678

17609 -0.204 RPTOR "regulatory associated protein of MTOR, complex 1" 0 0.85 0.11-1 4 0.5-7.1 57521 Q8N122

17610 -0.204 ERH enhancer of rudimentary homolog (Drosophila) 0 0.98 0.67-1 7.8 5.7-9.4 2079 P84090

17611 -0.205 ZNF253 zinc finger protein 253 0 0.63 0.04-0.95 1.1 -3-5.2 56242 O75346

17612 -0.206 EPRS glutamyl-prolyl-tRNA synthetase 0 0.93 0.19-1 6.4 3.7-7.9 2058 P07814

17613 -0.207 RPL9 ribosomal protein L9 0 0.99 0.77-1 10.3 8.1-12.3 6133 P32969

17614 -0.207 RPL12 ribosomal protein L12 0 1 0.97-1 10.7 8.2-12.7 6136 P30050

17615 -0.209 TANGO6 transport and golgi organization 6 homolog (Drosophila) 0 0.97 0.47-1 2.4 -0.6-5.1 79613 Q9C0B7

17616 -0.210 IARS2 "isoleucyl-tRNA synthetase 2, mitochondrial" 1 0.9 0.04-1 6.1 3.5-7.7 55699 Q9NSE4

17617 -0.211 RPL19 ribosomal protein L19 0 0.98 0.67-1 11 8.3-15 6143 P84098

17618 -0.212 ATP6V1A "ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A" 0 0.98 0.54-1 4.4 1.2-6.6 523 P38606

17619 -0.213 NDC80 NDC80 kinetochore complex component 0 0.98 0.55-1 4.9 0.7-7.4 10403 O14777

17620 -0.214 PSMB2 "proteasome (prosome, macropain) subunit, beta type, 2" 0 0.96 0.1-1 6.1 4.3-8 5690 P49721

17621 -0.215 RPL31 ribosomal protein L31 0 0.97 0.2-1 11.7 7.8-13.9 6160 P62899

17622 -0.217 RUVBL2 RuvB-like AAA ATPase 2 0 0.99 0.73-1 6.9 4.9-8.5 10856 Q9Y230

17623 -0.219 TBCC tubulin folding cofactor C 0 0.93 0.1-1 4.3 2.3-7.1 6903 Q15814

17624 -0.220 NUP133 nucleoporin 133kDa 0 0.97 0.32-1 4.5 2.4-6.3 55746 Q8WUM0

17625 -0.220 ISY1 ISY1 splicing factor homolog (S. cerevisiae) 0 0.95 0.27-1 5.1 2.4-6.9 57461

17626 -0.221 ZNF830 zinc finger protein 830 0 0.96 0.17-1 4.1 1.2-5.9 91603 Q96NB3

17627 -0.221 KPNB1 karyopherin (importin) beta 1 0 1 0.89-1 8 5.4-10.2 3837 Q14974

17628 -0.223 TOMM22 translocase of outer mitochondrial membrane 22 homolog (yeast) 1 0.97 0.68-1 6.1 4-8.1 56993 Q9NS69

17629 -0.226 RAD51 RAD51 recombinase 0 0.86 0.02-1 4.2 0.2-6.6 5888 Q06609

17630 -0.226 BYSL bystin-like 0 0.96 0.05-1 5 2.4-10.8 705 Q13895

17631 -0.227 RBM28 RNA binding motif protein 28 0 0.89 0.02-1 5.3 2-7.5 55131 Q9NW13

17632 -0.227 PSMA1 "proteasome (prosome, macropain) subunit, alpha type, 1" 0 1 0.9-1 7.6 5.9-10.2 5682 P25786

17633 -0.229 CHAF1B "chromatin assembly factor 1, subunit B (p60)" 0 1 0.93-1 3.4 -0.1-5.8 8208 Q13112

17634 -0.229 ALG14 "ALG14, UDP-N-acetylglucosaminyltransferase subunit" 0 0.92 0.04-1 2.1 -3-5.8 199857 Q96F25

17635 -0.232 ZNF492 zinc finger protein 492 0 0.84 0.08-1 -2 -3-3.7 57615 Q9P255

17636 -0.235 XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6 0 0.99 0.79-1 8.3 5.9-9.8 2547 P12956

17637 -0.235 RPS15A ribosomal protein S15a 1 0.99 0.28-1 11.1 8.8-13.3 6210 P62244

17638 -0.235 ATF4 activating transcription factor 4 0 0.8 0.03-1 8.7 6.7-10.7 468 P18848

17639 -0.237 ATP6V0B "ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b" 0 0.98 0.4-1 6.9 5.2-9.5 533 Q99437

17640 -0.240 RBBP5 retinoblastoma binding protein 5 0 0.92 0.08-1 3.5 1.2-5.7 5929 Q15291

17641 -0.240 NIP7 "NIP7, nucleolar pre-rRNA processing protein" 0 1 0.83-1 5.1 2.9-7.1 51388 Q9Y221

17642 -0.243 CDC16 cell division cycle 16 0 1 0.56-1 5.2 3-7.3 8881 Q13042

17643 -0.244 PRIM1 "primase, DNA, polypeptide 1 (49kDa)" 0 0.98 0.38-1 4.8 0.2-7.5 5557 P49642

17644 -0.246 TRAPPC1 trafficking protein particle complex 1 0 0.97 0.16-1 7.2 4.9-9 58485 Q9Y5R8

17645 -0.247 SDE2 SDE2 telomere maintenance homolog (S. pombe) 0 0.99 0.61-1 3.7 0.5-6.3 163859 Q6IQ49

17646 -0.249 UTP15 "UTP15, U3 small nucleolar ribonucleoprotein, homolog (S. cerevisiae)" 0 0.99 0.28-1 3.8 1.4-6.4 84135 Q8TED0

17647 -0.252 ALG11 "ALG11, alpha-1,2-mannosyltransferase" 0 0.98 0.53-1 2.8 -0.4-4.7 440138 Q2TAA5

17648 -0.254 EEF2 eukaryotic translation elongation factor 2 0 1 0.86-1 9.8 7.6-12.1 1938 P13639

17649 -0.255 SEC13 SEC13 homolog (S. cerevisiae) 0 0.98 0.61-1 6.6 4.6-10 6396 P55735

17650 -0.256 DONSON downstream neighbor of SON 0 1 0.38-1 4.8 2.3-7.3 29980 Q9NYP3

17651 -0.257 RPS28 ribosomal protein S28 0 0.98 0.09-1 8.8 5.3-11.4 6234 P62857

17652 -0.258 POLR2A "polymerase (RNA) II (DNA directed) polypeptide A, 220kDa" 0 0.99 0.81-1 5.8 2.2-8.4 5430 P24928

17653 -0.262 SMU1 smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans) 0 1 0.64-1 5.5 2.6-7 55234 Q2TAY7

17654 -0.262 RPL14 ribosomal protein L14 0 0.98 0.67-1 9.9 7.4-11.4 9045 P50914

17655 -0.264 NHP2L1 NHP2 non-histone chromosome protein 2-like 1 (S. cerevisiae) 0 0.97 0.36-1 6.8 4.9-8.8 4809 P55769

17656 -0.267 RRM2 ribonucleotide reductase M2 0 1 0.95-1 6.9 1.4-9.4 6241 P31350

17657 -0.274 PSMA2 "proteasome (prosome, macropain) subunit, alpha type, 2" 0 0.99 0.33-1 7.1 5.2-9.5 5683 P25787

17658 -0.279 MTRNR2L1 MT-RNR2-like 1 0 0.43 0.01-0.93 -3 -3--0.8 100462977 P0CJ68

17659 -0.280 EIF2S1 "eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa" 0 1 0.92-1 7.5 4.6-9.5 1965 P05198

17660 -0.283 PSMD3 "proteasome (prosome, macropain) 26S subunit, non-ATPase, 3" 0 0.98 0.13-1 6.8 4.9-11.5 5709 O43242

17661 -0.285 NEDD1 "neural precursor cell expressed, developmentally down-regulated 1" 0 0.99 0.39-1 4 0.8-6.1 121441 Q8NHV4

17662 -0.286 CDK1 cyclin-dependent kinase 1 0 0.99 0.5-1 6.2 1.3-9.6 983 P06493

17663 -0.288 UBA2 ubiquitin-like modifier activating enzyme 2 0 0.95 0.37-1 6.6 4.4-9.4 10054 Q9UBT2

17664 -0.290 DUT deoxyuridine triphosphatase 1 0.99 0.55-1 6.8 4.3-8.9 1854 P33316

17665 -0.292 MAK16 MAK16 homolog (S. cerevisiae) 0 0.99 0.81-1 3.8 1.2-8.1 84549 Q9BXY0

17666 -0.294 DNAJC17 "DnaJ (Hsp40) homolog, subfamily C, member 17" 0 0.99 0.67-1 4.2 2.2-6.4 55192 Q9NVM6

17667 -0.296 QARS glutaminyl-tRNA synthetase 0 0.98 0.25-1 7.3 4.8-8.6 5859 P47897

17668 -0.304 RAE1 ribonucleic acid export 1 0 0.97 0.09-1 5.5 3.3-8.5 8480 P78406

17669 -0.306 NIFK nucleolar protein interacting with the FHA domain of MKI67 0 0.97 0.38-1 5.7 3.6-7.9 84365 Q9BYG3

17670 -0.311 GINS2 GINS complex subunit 2 (Psf2 homolog) 0 1 0.86-1 4.1 -0.6-7.2 51659 Q9Y248

17671 -0.329 RPL7 ribosomal protein L7 0 0.98 0.37-1 11.3 8.7-14.1 6129 P18124

17672 -0.335 POLR3B polymerase (RNA) III (DNA directed) polypeptide B 0 0.98 0.66-1 2.5 -0.1-4.5 55703 Q9NW08

17673 -0.335 CDK9 cyclin-dependent kinase 9 0 0.96 0.34-1 5.4 3.1-7.9 1025 P50750

17674 -0.351 C21orf59 chromosome 21 open reading frame 59 0 0.97 0.23-1 5.7 3.3-8.1 56683 P57076