Samantha J. Riesenfeld


Aereal photo of Chicago from Hyde Park

I will be moving to the University of Chicago this fall to become an Assistant Professor at the exciting new Pritzker School of Molecular Engineering, as well as in the Biological Sciences Division's excellent Section of Genetic Medicine.


I am currently a postdoctoral associate in the Regev lab at the Broad Institute and the Kuchroo lab at Brigham and Women's Hospital and Harvard Medical School. My research focuses on developing and using data science approaches to analyze single-cell transcriptomic data, with the goal of learning about the intra- and intercellular circuits that regulate gene expression and cellular function.

My current work has a particular focus on immune cell biology, specifically, on the activation, function, and plasticity of innate lymphoid cells (ILCs) in different mucosal barrier tissues. I am also very interested in how the immune system and nervous system interact to respond to provocation, particularly in type 2 inflammation.

Previously, as a postdoc in the Pollard lab at the Gladstone Institutes, I collaborated with the Ahituv lab to use transgenic zebrafish to characterize very short enhancer-like sequences. I also worked on methods for the evolutionary analysis of metagenomic data, i.e., fragments of microbial DNA extracted directly from uncultured environmental samples via high-throughput sequencing.

I have a PhD in Computer Science from UC Berkeley and a BA in Mathematics and Computer Science from Harvard University. As a graduate student, I was advised by Richard Karp in the Theory Group at UC Berkeley, where my research focused on combinatorial optimization and approximation algorithms.

Adapted from template design by Andreas Viklund