Differentially expressed genes (DEGs) for Alzheimer's disease measurements and AD*sex interaction.

DEGs are aggregated into tables by cell type. Results are included for all major cell type groups (Ast, Inh, Exc, Mic, CAM, T cell, Opc, Oli, vascular subtypes) and for excitatory neuron subtypes.

Tsv table columns include:
gene - HGNC gene symbol
path - AD variable used for DEG analysis
region - Which of the regions the DEG analysis is run on (or all regions jointly)
col_nm - Final call on DEG status. Only genes where both Nebula and MAST are significant + in the same direction are labeled as DEGs. 0: Not significant, 1: Down-regulated, 2: Up-regulated.
log10p_nm - Sum of the log10p-values from Nebula and MAST.
logFC_nb - Nebula logFC
coef_mast - MAST coefficient

Please contact authors if you need the raw DEG results from either method.

For the AD*sex interaction, all results are collated. The interaction model is between pathology diagnosis of AD (nrad) and sex (msex, where 0: F and 1: M). Table columns include:
gene,  path, region - as above, but "path" is only msex for these results. 
logFC_nradAD_nb, logFC_msex:nradAD_nb - logFC for Nebula for msex:0+AD (nradAD) and msex:1+AD (msex:nradAD)
coef_nradAD_mast, coef_msex:nradAD_mast - coefficients for MAST both interactions
log10p_nradAD_nm, log10p_msex:nradAD_nm - Sum of log10 p-values from MAST and Nebula for both interactions
col_nradAD_nm, col_msex:nradAD_nm - DEG calls for both interactions, as above.

AD variables used:
nrad - Pathology diagnosis of AD, by NIA-Reagan score (1-2: AD, 3-4: non-AD)
cogdxad - Cognitive diagnosis of AD, by consensus clinical diagnosis (AD vs. non-AD)
nft - NFT density in the region
plaq_n - Neuritic plaque density in the region 
plaq_d - Diffuse plaque density in the region 
msex - Sex, with 0: F and 1: M
braaksc.early - Non-Early vs. Middle-Late Braak (0-2 vs. 3-6)
braaksc.ad - Non-Middle vs. Late Braak scores (0-4 vs. 5-6)