Publications

Updated by Buhm Han on December 3, 2014

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-- The publication list on this site is no longer maintained, since I moved to Asan Medical Center, Korea. Please visit our new site

    2014
  1. Jong Wha J Joo,Jae Hoon Sul, Buhm Han, Chun Ye, Eleazar Eskin. "Effectively identifying regulatory hotspots while capturing expression heterogeneity in gene expression studies." Genome Biology. 2014. In Press.

  2. Buhm Han, Dorothee Diogo, Steve Eyre, Henrik Kallberg, Alexandra Zhernakova, John Bowes, Leonid Padyukov, Yukinori Okada, Miguel A. Gonzalez-Gay, Solbritt Rantapaa-Dahlqvist, Javier Martin, Tom W J Huzinga, Robert Plenge, Jane Worthington, Peter K. Gregersen, Lars Klareskog, Paul I. W. de Bakker, Soumya Raychaudhuri. "Fine-mapping seronegative and seropositive rheumatoid arthritis to shared and distinct HLA alleles by adjusting for the effects of heterogeneity." The American Journal of Human Genetics. 94(4):522-523. 2014.

  3. 2013
  4. Buhm Han*, Eun Yong Kang*, Soumya Raychaudhuri, Paul I. W. de Bakker, Eleazar Eskin. "Fast Pairwise IBD Association Testing in Genome-wide Association Studies." Bioinformatics. [Epub ahead of print] doi:10.1093/bioinformatics/btt609. 2013.
    * : Equal contribution.

  5. Annie Yarwood, Buhm Han, Soumya Raychaudhuri, John Bowes, Mark Lunt, Dimitrios A Pappas, Joel Kremer, Jeffrey D Greenberg, Robert Plenge, Rheumatoid Arthritis Consortium International (RACI), Jane Worthington, Anne Barton, Steve Eyre. "A weighted genetic risk score using all known susceptibility variants to estimate rheumatoid arthritis risk." Annals of Rheumatic Diseases. [Epub ahead of print] doi:10.1136/annrheumdis-2013-204133. 2013

  6. Eun Yong Kang*, Buhm Han*, Nicholas Furlotte*, Jong Wha Joo, Diana Shih, Richard Davis, Aldons J. Lusis, Eleazar Eskin. "Meta-analysis identifies gene-by-environment interactions as demonstrated in a study of 4,965 mice." PLOS Genetics. 10(1): e1004022. 2013.
    * : Equal contribution.

  7. Xinli Hu, Hyun Kim, Patrick J. Brennan, Buhm Han, Clare Baecher-Allan, Philip De Jager, Michael B. Brenner, Soumya Raychaudhuri. "Application of user-guided automated cytometric data analysis to large-scale immunoprofiling of invariant natural killer T cells." Proceedings of the National Academy of Sciences. 110(47):19030-5. 2013.

  8. Dan He, Zhanyong Wang, Buhm Han, Laxmi Parida, Eleazar Eskin. "IPED: Inheritance Path Based Pedigree Reconstruction Algorithm Using Genotype Data." Journal of Computarional Biology. 20(10):780-91. 2013.

  9. Jae Hoon Sul*, Buhm Han*, Chun Ye*, Ted Choi, Eleazar Eskin. "Effectively identifying eQTLs from multiple tissues by combining mixed model and meta-analytic approaches." PLoS Genetics. 9(6): e1003491. 2013.
    * : Equal contribution.

  10. Xiaoming Jia*, Buhm Han*, Suna Onengut-Gumuscu, Wei-Min Chen, Patrick J. Concannon, Stephen S. Rich, Soumya Raychaudhuri, Paul I.W. de Bakker. "Imputing Amino Acid Polymorphisms in Human Leukocyte Antigenes." PLoS One. 8(6):e64683. 2013.
    * : Equal contribution.

  11. Oron Navon, Jae Hoon Sul, Buhm Han, Lucia Conde, Paige Bracci, Jacques Riby, Christine Skibola, Eleazar Eskin, Eran Halperin. "Rare Variant Association Testing under Low-Coverage Sequencing." Genetics. 194(3):769-79. 2013.

  12. Scharf JM, Yu D, Mathews CA, Neale BM, Stewart SE, Fagerness JA, Evans P, Gamazon E, Edlund CK, Service SK, Tikhomirov A, Osiecki L, Illmann C, Pluzhnikov A, Konkashbaev A, Davis LK, Han B, Crane J, Moorjani P, Crenshaw AT, Parkin MA, Reus VI, Lowe TL, Rangel-Lugo M, Chouinard S, Dion Y, Girard S, Cath DC, Smit JH, King RA, Fernandez TV, Leckman JF, Kidd KK, Kidd JR, Pakstis AJ, State MW, Herrera LD, Romero R, Fournier E, Sandor P, Barr CL, Phan N, Gross-Tsur V, Benarroch F, Pollak Y, Budman CL, Bruun RD, Erenberg G, Naarden AL, Lee PC, Weiss N, Kremeyer B, BerrĂ­o GB, Campbell DD, Cardona Silgado JC, Ochoa WC, Mesa Restrepo SC, Muller H, Valencia Duarte AV, Lyon GJ, Leppert M, Morgan J, Weiss R, Grados MA, Anderson K, Davarya S, Singer H, Walkup J, Jankovic J, Tischfield JA, Heiman GA, Gilbert DL, Hoekstra PJ, Robertson MM, Kurlan R, Liu C, Gibbs JR, Singleton A; for the North American Brain Expression Consortium, Hardy J; for the UK Human Brain Expression Database, Strengman E, Ophoff RA, Wagner M, Moessner R, Mirel DB, Posthuma D, Sabatti C, Eskin E, Conti DV, Knowles JA, Ruiz-Linares A, Rouleau GA, Purcell S, Heutink P, Oostra BA, McMahon WM, Freimer NB, Cox NJ, Pauls DL. "Genome-wide association study of Tourettes syndrome." Molecular Psychiatry. 18(6):721-8. 2013.

  13. Dan He, Zhanyong Wang, Buhm Han, Laxmi Parida, Eleazar Eskin. "IPED: Inheritance Path Based Pedigree Reconstruction Algorithm Using Genotype Data." In Proceedings of the Seventeenth Annual Conference on Research in Computational Molecular Biology (RECOMB-2013). Beijing, China: April 7-10, 2013.

  14. Dan He, Buhm Han, Eleazar Eskin. "Hap-seq: An Optimal Algorithm for Haplotype Phasing with Imputation using Sequencing." Journal of computational biology. 20(2):80-92. 2013.

  15. Gosia Trynka, Cynthia Sandor, Buhm Han, Han Xu, Barbara E Stranger, X Shirley Liu, Soumya Raychaudhuri. "Chromatin marks identify critical cell types for fine mapping complex trait variants." Nature Genetics. 45(2):124-30. 2013.

  16. 2012
  17. Gregory Darnell, Dat Duong, Buhm Han, Eleazar Eskin. "Incorporating Prior Information Into Association Studies." Bioinformatics. 28 (12): i147-i153, 2012. also in Proceedings of the Twentieth Annual Conference on Intelligent Systems for Molecular Biology (ISMB-2012).

  18. Buhm Han, Eleazar Eskin. "Interpreting Meta-Analysis of Genome-Wide Association Studies." PLoS Genetics. 8(3):e1002555, 2012.

  19. Dan He, Buhm Han, Eleazar Eskin. "Hap-seq: An Optimal Algorithm for Haplotype Phasing with Imputation using Sequencing Data." In Proceedings of the Sixteenth Annual Conference on Research in Computational Molecular Biology (RECOMB-2012). Barcelona, Spain: April 21-24, 2012.

  20. 2011
  21. Jae Hoon Sul, Buhm Han, Eleazar Eskin. "Increasing Power of Groupwise Association Test with Likelihood Ratio Test." Journal of Computational Biology. 18(11):1611-1624, 2011.

  22. Buhm Han, Eleazar Eskin. "Random-Effects Model Aimed at Discovering Associations in Meta-Analysis of Genome-wide Association Studies." The American Journal of Human Genetics. 88(5):586-598, 2011.

  23. Jae Hoon Sul, Buhm Han, Dan He, Eleazar Eskin. "An Optimal Weighted Aggregated Association Test for Identification of Rare Variants Involved in Common Diseases." Genetics. 188(1):181-8, 2011.

  24. Jae Hoon Sul, Buhm Han, Eleazar Eskin. "Increasing Power of Groupwise Association Test with Likelihood Ratio Test." In Proceedings of the Fifteenth Annual Conference on Research in Computational Molecular Biology (RECOMB-2011). Vancouver, Canada: March 28-31, 2011.

  25. Buhm Han, Brian Hackel, Eleazar Eskin. "Postassociation Cleaning Using Linkage Disequilibrium Information." Genetic Epidemiology. 35(1):1-10, 2011.

  26. 2010
  27. Andrew Kirby, Hyun Min Kang, Claire M. Wade, Chris Cotsapas, Emrah Kostem, Buhm Han, Nick Furlotte, Eun Yong Kang, Manuel Rivas, Molly A. Bogue, Kelly A. Frazer, Frank M. Johnson, Erica J. Beilharz, David R. Cox, Eleazar Eskin, Mark J. Daly. "Fine Mapping in 94 Inbred Mouse Strains Using a High-Density Haplotype Resource." Genetics. 185(3):1081-1095, 2010.

  28. Buhm Han, Eleazar Eskin. "Multiple Testing in Genetic Epidemiology." Encyclopedia of Life Sciences. DOI:10.1002/9780470015902.a0022497, 2010.

  29. 2009
  30. Buhm Han, Chun Ye, Ted Choi, Eleazar Eskin. "Leveraging Joint Test Status Distribution for an Optimal Signicance Testing." NIPS 2009 Workshop on Machine Learning in Computational Biology. Whistler, CA: December 11th, 2009.

  31. Hyun Min Kang, Noah Zaitlen, Buhm Han, Eleazar Eskin. "An Adaptive and Memory Efficient Algorithm for Genotype Imputation." In Proceedings of the Thirteenth Annual Conference on Research in Computational Molecular Biology (RECOMB-2009). Tucson, AZ: May 18th-21st, 2009.

  32. Buhm Han, Hyun Min Kang, Eleazar Eskin. "Rapid and Accurate Multiple Testing Correction and Power Estimation for Millions of Correlated Markers." PLoS Genetics. 5:4,e1000456, 2009.

  33. 2008
  34. Arthur Choi, Noah Zaitlen, Buhm Han, Knot Pipatsrisawat, Adnan Darwiche, Eleazar Eskin. "Efficient Genome Wide Tagging by Reduction to SAT." In Proceedings of the 8th Workshop on Algorithms in Bioinformatics (WABI-2008). Universitt Karlsruhe, Germany: September 15-17, 2008.

  35. Buhm Han*, Banu Dost*, Vineet Bafna, Shaojie Zhang. "Structural Alignment of Pseudoknotted RNA." Journal of Computational Biology. 15(5):489-504, 2008.

  36. Buhm Han, Hyun Min Kang, Myeong Seong Seo, Noah Zaitlen, Eleazar Eskin. "Efficient Association Study Design via Power-Optimized Tag SNP Selection." Annals of Human Genetics. 72(6):834-47, 2008.

  37. 2006
  38. Banu Dost*, Buhm Han*, Shaojie Zhang, Vineet Bafna. "Structural Alignment of Pseudoknotted RNA." In Proceedings of the Tenth Annual Conference on Research in Computational Molecular Biology (RECOMB-2006). Venice, Italy, April 2-5, 2006.

  39. * : Equal contribution.